P36175 (GCP_PASHA) Reviewed, UniProtKB/Swiss-Prot
Last modified
September 21, 2011.
Version 67.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp Alternative name(s): t(6)A37 threonylcarbamoyladenosine biosynthesis protein | ||
| Gene names |
| ||
| Organism | Pasteurella haemolytica (Mannheimia haemolytica) | ||
| Taxonomic identifier | 75985 [NCBI] | ||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Mannheimia |
Protein attributes
| Sequence length | 325 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Function | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445 |
| Subcellular location | Secreted. Note: Not secreted through the conventional secretory pathway since it lacks a signal sequence. HAMAP MF_01445 |
| Sequence similarities | Belongs to the KAE1 / YgjD family. |
| Caution | Was originally thought to have endopeptidase activity (Ref.1). But it could not be confirmed with orthologs purified from P. abyssi (PubMed:17766251, PubMed:21183954). |
Ontologies
| Keywords | |
|---|---|
| Biological process | tRNA processing |
| Cellular component | Secreted |
| Technical term | Direct protein sequencing |
| Gene Ontology (GO) | |
| Biological process | proteolysis Inferred from electronic annotation. Source: InterPro tRNA processingInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 325 | 325 | Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445 | PRO_0000096976 | |||
Sequences
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References
| [1] | "Cloning, nucleotide sequence, and expression of the Pasteurella haemolytica A1 glycoprotease gene." Abdullah K.M., Lo R.Y.C., Mellors A. J. Bacteriol. 173:5597-5603(1991) [PubMed: 1885539] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE. Strain: Serotype A1. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | U15958 Genomic DNA. Translation: AAA80282.1. |
| PIR | A38108. |
3D structure databases | |
| ProteinModelPortal | P36175. |
| ModBase | Search... |
Protein family/group databases | |
| MEROPS | M22.001. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Family and domain databases | |
| HAMAP | MF_01445. gcp. [Tree] |
| InterPro | IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view] |
| Pfam | PF00814. Peptidase_M22. 1 hit. [Graphical view] |
| PRINTS | PR00789. OSIALOPTASE. |
| TIGRFAMs | TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit. |
| PROSITE | PS01016. GLYCOPROTEASE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | GCP_PASHA | ||||||||
| Accession | Primary (citable) accession number: P36175 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

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