Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P36164

- TVP38_YEAST

UniProt

P36164 - TVP38_YEAST

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Golgi apparatus membrane protein TVP38

Gene

TVP38

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli

Functioni

Golgi membrane protein involved in vesicular trafficking and spindle migration.1 Publication

GO - Biological processi

  1. mitotic spindle elongation Source: SGD
  2. vesicle-mediated transport Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-32051-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Golgi apparatus membrane protein TVP38
Alternative name(s):
TLG2-vesicle protein of 38 kDa
Gene namesi
Name:TVP38
Ordered Locus Names:YKR088C
ORF Names:YKR408
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome XI

Organism-specific databases

CYGDiYKR088c.
SGDiS000001796. TVP38.

Subcellular locationi

Golgi apparatus membrane 3 Publications; Multi-pass membrane protein 3 Publications

GO - Cellular componenti

  1. integral component of Golgi membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 337337Golgi apparatus membrane protein TVP38PRO_0000203226Add
BLAST

Proteomic databases

PaxDbiP36164.

Expressioni

Gene expression databases

GenevestigatoriP36164.

Interactioni

Subunit structurei

Interacts with YIP5.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
AKR1P390101EBI-26527,EBI-2421
GCS1P351971EBI-26527,EBI-7475
KEX1P096201EBI-26527,EBI-9653
RBD2Q122701EBI-26527,EBI-31471
TEF1P029941EBI-26527,EBI-6314
TVP15Q038601EBI-26527,EBI-37537

Protein-protein interaction databases

BioGridi34219. 34 interactions.
DIPiDIP-5167N.
IntActiP36164. 6 interactions.
MINTiMINT-563946.
STRINGi4932.YKR088C.

Structurei

3D structure databases

ProteinModelPortaliP36164.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 9595LumenalSequence AnalysisAdd
BLAST
Topological domaini117 – 13721CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini159 – 16911LumenalSequence AnalysisAdd
BLAST
Topological domaini191 – 25161CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini273 – 28614LumenalSequence AnalysisAdd
BLAST
Topological domaini308 – 33730CytoplasmicSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei96 – 11621HelicalSequence AnalysisAdd
BLAST
Transmembranei138 – 15821HelicalSequence AnalysisAdd
BLAST
Transmembranei170 – 19021HelicalSequence AnalysisAdd
BLAST
Transmembranei252 – 27221HelicalSequence AnalysisAdd
BLAST
Transmembranei287 – 30721HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the TVP38/TMEM64 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0398.
HOGENOMiHOG000066098.
InParanoidiP36164.
OMAiFPYSLTN.
OrthoDBiEOG744TMD.

Family and domain databases

InterProiIPR015414. SNARE_assoc.
[Graphical view]
PfamiPF09335. SNARE_assoc. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P36164-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSQSYEAGNA NMGQGEDDEF DGYFEDFDND IMPNSNNGQR VGTNAGLSFN
60 70 80 90 100
DEVNVNDDDF LDIYNMSPRE RLMHNIRKNV QKLQFYFYSL RLWQQIIIVL
110 120 130 140 150
LGIMLMIMGI LLLVFHNAIL HKVVVTSNDL REKMSTHFIL MVLIFFVAFP
160 170 180 190 200
PMIGYSLLST TTGLIYGVSF EGWVTLALGS VTGSIASFVV FKTILHSRAE
210 220 230 240 250
KLVHLNRRFE ALASILQENN SYWILALLRL CPFPYSLTNG AIAGVYGISV
260 270 280 290 300
RNFSIANIIT TPKLFIYLFI GSRVKSLAES ESTGSRVFDL VSIIITLLIL
310 320 330
SLTAWLLYFK TKKRYLELQN RDRQVSTDQL PELSFEV
Length:337
Mass (Da):38,311
Last modified:June 1, 1994 - v1
Checksum:i7EA95DD4E5AF77FE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z27116 Genomic DNA. Translation: CAA81639.1.
Z28313 Genomic DNA. Translation: CAA82167.1.
AY557916 Genomic DNA. Translation: AAS56242.1.
BK006944 Genomic DNA. Translation: DAA09238.1.
PIRiS38166.
RefSeqiNP_013014.3. NM_001179878.3.

Genome annotation databases

EnsemblFungiiYKR088C; YKR088C; YKR088C.
GeneIDi853963.
KEGGisce:YKR088C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z27116 Genomic DNA. Translation: CAA81639.1 .
Z28313 Genomic DNA. Translation: CAA82167.1 .
AY557916 Genomic DNA. Translation: AAS56242.1 .
BK006944 Genomic DNA. Translation: DAA09238.1 .
PIRi S38166.
RefSeqi NP_013014.3. NM_001179878.3.

3D structure databases

ProteinModelPortali P36164.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 34219. 34 interactions.
DIPi DIP-5167N.
IntActi P36164. 6 interactions.
MINTi MINT-563946.
STRINGi 4932.YKR088C.

Proteomic databases

PaxDbi P36164.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YKR088C ; YKR088C ; YKR088C .
GeneIDi 853963.
KEGGi sce:YKR088C.

Organism-specific databases

CYGDi YKR088c.
SGDi S000001796. TVP38.

Phylogenomic databases

eggNOGi COG0398.
HOGENOMi HOG000066098.
InParanoidi P36164.
OMAi FPYSLTN.
OrthoDBi EOG744TMD.

Enzyme and pathway databases

BioCyci YEAST:G3O-32051-MONOMER.

Miscellaneous databases

NextBioi 975392.

Gene expression databases

Genevestigatori P36164.

Family and domain databases

InterProi IPR015414. SNARE_assoc.
[Graphical view ]
Pfami PF09335. SNARE_assoc. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The complete sequence of an 18,002 bp segment of Saccharomyces cerevisiae chromosome XI contains the HBS1, MRP-L20 and PRP16 genes, and six new open reading frames."
    Garcia-Cantalejo J.M., Baladron V., Esteban P.F., Santos M.A., Bou G., Remacha M.A., Revuelta J.L., Ballesta J.P.G., Jimenez A., del Rey F.
    Yeast 10:231-245(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Complete DNA sequence of yeast chromosome XI."
    Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C.
    , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
    Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  5. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  7. "Immunoisolaton of the yeast Golgi subcompartments and characterization of a novel membrane protein, Svp26, discovered in the Sed5-containing compartments."
    Inadome H., Noda Y., Adachi H., Yoda K.
    Mol. Cell. Biol. 25:7696-7710(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION, IDENTIFICATION BY MASS SPECTROMETRY.
  8. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
    Kim H., Melen K., Oesterberg M., von Heijne G.
    Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: ATCC 208353 / W303-1A.
  9. "Tvp38, Tvp23, Tvp18 and Tvp15: novel membrane proteins in the Tlg2-containing Golgi/endosome compartments of Saccharomyces cerevisiae."
    Inadome H., Noda Y., Kamimura Y., Adachi H., Yoda K.
    Exp. Cell Res. 313:688-697(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH YIP5.
  10. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
    Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
    Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  11. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
    Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
    Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiTVP38_YEAST
AccessioniPrimary (citable) accession number: P36164
Secondary accession number(s): D6VXE8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: October 29, 2014
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 11300 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome XI
    Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

External Data

Dasty 3