P36158 (YK58_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein YKR078W

Gene names

Ordered Locus Names:

YKR078W

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	585 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Miscellaneous

Present with 1270 molecules/cell in log phase SD medium.

Ontologies

Keywords
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell communication Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from direct assay PubMed 14562095. Source: SGD
Molecular_function	phosphatidylinositol-3-phosphate binding Inferred from direct assay PubMed 11557775. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 585	585	Uncharacterized protein YKR078W		PRO_0000203224
Amino acid modifications
	Modified residue	496	1	Phosphoserine Ref.4

Sequences

	Sequence		Length	Mass (Da)
	P36158 [UniParc]. Last modified June 1, 1994. Version 1. Checksum: 45677C7B39E1235E	FASTA	585	68,281
	10 20 30 40 50 60 MENDKASHAS PSIGVNEFVV QGEISIDDSE RSVKSVSVSI SDDEDSKTDV QDNMATPSTR 70 80 90 100 110 120 SKFQTDLAID NRLLEKDPKY KKLFTEKRRR RRPESCINLM TKGKGTGQKD NINDQIFSLR 130 140 150 160 170 180 ILPGSDLNSL KDSLWIIKIS TQPDVEKTIA RAFSDFYWLY HQLQNNHWGK TIPPPTRSNI 190 200 210 220 230 240 LVEKDEFAIN HLFMIRNNEK YDPIFNFKPE YIISLQLMAM IKHIFNDKVL RLDSNFIDFI 250 260 270 280 290 300 SWDDDLPESL QIVVDDSTFT GDKILMTSSQ FRELKEFHKQ SKKVESITNS HASLIPVTEL 310 320 330 340 350 360 TEIYISPTKL FSRKDYQRLF QPQSTDNTFN NNDPLIQEWI PKSKTLFTSL SFGSSAPTYQ 370 380 390 400 410 420 EASTEIQACH DWVSISKEQW KQLLYHVLQY IVDEAVKVNS VINEFTECLK QISLDEVIRA 430 440 450 460 470 480 NSELFLKFSK LNESFLKKFK GASRQDILKL IILFDENVRF CESFESILNQ RLKLGKILSI 490 500 510 520 530 540 IEVDLDKKKN FLDKLSPGNN NSNNEDLKIR TAEDEYRIVL KRYNRVKQSW EKIMEDILNE 550 560 570 580 RKEFEKREAA EVNSCLKSIR DLNMDEKKHY LQLWQDFVPD EHISQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete DNA sequence of yeast chromosome XI." Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C. , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W. Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[4]	"Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases." Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H. Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-496, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z28303 Genomic DNA. Translation: CAA82157.1. BK006944 Genomic DNA. Translation: DAA09228.1.
PIR	S38155.
RefSeq	NP_013004.3. NM_001179868.3.
3D structure databases
ProteinModelPortal	P36158.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-7328N.
MINT	MINT-604524.
STRING	4932.YKR078W.
Proteomic databases
PaxDb	P36158.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YKR078W; YKR078W; YKR078W.
GeneID	853953.
KEGG	sce:YKR078W. sce:YKR080W.
Organism-specific databases
CYGD	YKR078w.
SGD	S000001786. YKR078W.
Phylogenomic databases
eggNOG	COG5391.
KO	K00295.
Gene expression databases
Genevestigator	P36158.
GermOnline	YKR078W. Saccharomyces cerevisiae.
Family and domain databases
Gene3D	3.30.1520.10. 1 hit.
InterPro	IPR001683. Phox. IPR015404. Vps5_C. [Graphical view]
Pfam	PF00787. PX. 1 hit. PF09325. Vps5. 1 hit. [Graphical view]
SMART	SM00312. PX. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	975362.

Entry information

Entry name

YK58_YEAST

Accession

Primary (citable) accession number: P36158
Secondary accession number(s): D6VXD8

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 1, 1994
Last sequence update:	June 1, 1994
Last modified:	April 3, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program