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P36157

- MSA2_YEAST

UniProt

P36157 - MSA2_YEAST

Protein

Putative transcriptional activator MSA2

Gene

MSA2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 83 (01 Oct 2014)
      Sequence version 1 (01 Jun 1994)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. regulation of transcription involved in G1/S transition of mitotic cell cycle Source: SGD
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulation

    Enzyme and pathway databases

    BioCyciYEAST:G3O-32041-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative transcriptional activator MSA2
    Alternative name(s):
    MBF and SBF-associated protein 2
    Gene namesi
    Name:MSA2
    Ordered Locus Names:YKR077W
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome XI

    Organism-specific databases

    CYGDiYKR077w.
    SGDiS000001785. MSA2.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 363363Putative transcriptional activator MSA2PRO_0000203223Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei157 – 1571Phosphoserine1 Publication
    Modified residuei292 – 2921Phosphoserine1 Publication

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiP36157.
    PaxDbiP36157.

    Expressioni

    Gene expression databases

    GenevestigatoriP36157.

    Interactioni

    Subunit structurei

    Interacts with transcription complexes SCB-binding factor (SBF) and MCB-binding factor (MBF). Interacts with SWI4.1 Publication

    Protein-protein interaction databases

    BioGridi34208. 39 interactions.
    DIPiDIP-2702N.
    IntActiP36157. 7 interactions.
    MINTiMINT-1548078.
    STRINGi4932.YKR077W.

    Structurei

    3D structure databases

    ProteinModelPortaliP36157.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG12793.
    OMAiHIDEVIP.
    OrthoDBiEOG7NCVDF.

    Sequencei

    Sequence statusi: Complete.

    P36157-1 [UniParc]FASTAAdd to Basket

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    MVYTTPQQQQ RFSSTPQSSH TLIFSPIRAP SMQTPSSLDY QSPSIVVSSS    50
    SMKVHGRSSS FGKFSLSIGQ NGKATILGPI NVLPTDTSKM EKPVPKKKPV 100
    TSDRVEKTRI LSLLKKMRNK SSTVNKKYSK VPLKSTTSLQ PAATAPSPLV 150
    SNIIKPSPKK LASPRTPNAN SNLNLNFTSF QIKTGFTPNL DGILLENFTS 200
    PNTTADSQGN SASNIINNNH GSANNTNQFL FNLPLQSSPR QFRSPARLID 250
    PLPISDWNTS LLMSPPRTTN FESANNHFNS NFAQASMLRR PSLPHIDEVI 300
    PQDSNPANYS DRSDYLSVDQ NANNHNGALS EQTYNNIMKS SMISLPIEKD 350
    DATMALRKLV SRE 363
    Length:363
    Mass (Da):39,862
    Last modified:June 1, 1994 - v1
    Checksum:iD6E5DA379605650A
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti122 – 1221S → R in AAS56248. (PubMed:17322287)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z28302 Genomic DNA. Translation: CAA82156.1.
    AY557922 Genomic DNA. Translation: AAS56248.1.
    BK006944 Genomic DNA. Translation: DAA09227.1.
    PIRiS38154.
    RefSeqiNP_013003.1. NM_001179867.1.

    Genome annotation databases

    EnsemblFungiiYKR077W; YKR077W; YKR077W.
    GeneIDi853952.
    KEGGisce:YKR077W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z28302 Genomic DNA. Translation: CAA82156.1 .
    AY557922 Genomic DNA. Translation: AAS56248.1 .
    BK006944 Genomic DNA. Translation: DAA09227.1 .
    PIRi S38154.
    RefSeqi NP_013003.1. NM_001179867.1.

    3D structure databases

    ProteinModelPortali P36157.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 34208. 39 interactions.
    DIPi DIP-2702N.
    IntActi P36157. 7 interactions.
    MINTi MINT-1548078.
    STRINGi 4932.YKR077W.

    Proteomic databases

    MaxQBi P36157.
    PaxDbi P36157.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YKR077W ; YKR077W ; YKR077W .
    GeneIDi 853952.
    KEGGi sce:YKR077W.

    Organism-specific databases

    CYGDi YKR077w.
    SGDi S000001785. MSA2.

    Phylogenomic databases

    eggNOGi NOG12793.
    OMAi HIDEVIP.
    OrthoDBi EOG7NCVDF.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-32041-MONOMER.

    Miscellaneous databases

    NextBioi 975359.

    Gene expression databases

    Genevestigatori P36157.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Complete DNA sequence of yeast chromosome XI."
      Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C.
      , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
      Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    6. "The SBF- and MBF-associated protein Msa1 is required for proper timing of G1-specific transcription in Saccharomyces cerevisiae."
      Ashe M., de Bruin R.A.M., Kalashnikova T., McDonald W.H., Yates J.R. III, Wittenberg C.
      J. Biol. Chem. 283:6040-6049(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY, INTERACTION WITH SWI4; SBF AND MBF COMPLEXES.
    7. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
      Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
      Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-157 AND SER-292, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiMSA2_YEAST
    AccessioniPrimary (citable) accession number: P36157
    Secondary accession number(s): D6VXD7, Q6Q5M8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 1, 1994
    Last sequence update: June 1, 1994
    Last modified: October 1, 2014
    This is version 83 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 861 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    2. Yeast chromosome XI
      Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

    External Data

    Dasty 3