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P36157 (MSA2_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative transcriptional activator MSA2
Alternative name(s):
MBF and SBF-associated protein 2
Gene names
Name:MSA2
Ordered Locus Names:YKR077W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length363 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Interacts with transcription complexes SCB-binding factor (SBF) and MCB-binding factor (MBF). Interacts with SWI4. Ref.6

Miscellaneous

Present with 861 molecules/cell in log phase SD medium.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 363363Putative transcriptional activator MSA2
PRO_0000203223

Amino acid modifications

Modified residue1571Phosphoserine Ref.7
Modified residue2921Phosphoserine Ref.7

Experimental info

Sequence conflict1221S → R in AAS56248. Ref.3

Sequences

Sequence LengthMass (Da)Tools
P36157 [UniParc].

Last modified June 1, 1994. Version 1.
Checksum: D6E5DA379605650A

FASTA36339,862
        10         20         30         40         50         60 
MVYTTPQQQQ RFSSTPQSSH TLIFSPIRAP SMQTPSSLDY QSPSIVVSSS SMKVHGRSSS 

        70         80         90        100        110        120 
FGKFSLSIGQ NGKATILGPI NVLPTDTSKM EKPVPKKKPV TSDRVEKTRI LSLLKKMRNK 

       130        140        150        160        170        180 
SSTVNKKYSK VPLKSTTSLQ PAATAPSPLV SNIIKPSPKK LASPRTPNAN SNLNLNFTSF 

       190        200        210        220        230        240 
QIKTGFTPNL DGILLENFTS PNTTADSQGN SASNIINNNH GSANNTNQFL FNLPLQSSPR 

       250        260        270        280        290        300 
QFRSPARLID PLPISDWNTS LLMSPPRTTN FESANNHFNS NFAQASMLRR PSLPHIDEVI 

       310        320        330        340        350        360 
PQDSNPANYS DRSDYLSVDQ NANNHNGALS EQTYNNIMKS SMISLPIEKD DATMALRKLV 


SRE 

« Hide

References

« Hide 'large scale' references
[1]"Complete DNA sequence of yeast chromosome XI."
Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C. expand/collapse author list , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[5]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[6]"The SBF- and MBF-associated protein Msa1 is required for proper timing of G1-specific transcription in Saccharomyces cerevisiae."
Ashe M., de Bruin R.A.M., Kalashnikova T., McDonald W.H., Yates J.R. III, Wittenberg C.
J. Biol. Chem. 283:6040-6049(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY, INTERACTION WITH SWI4; SBF AND MBF COMPLEXES.
[7]"Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-157 AND SER-292, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z28302 Genomic DNA. Translation: CAA82156.1.
AY557922 Genomic DNA. Translation: AAS56248.1.
BK006944 Genomic DNA. Translation: DAA09227.1.
PIRS38154.
RefSeqNP_013003.1. NM_001179867.1.

3D structure databases

ProteinModelPortalP36157.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid34208. 39 interactions.
DIPDIP-2702N.
IntActP36157. 7 interactions.
MINTMINT-1548078.
STRING4932.YKR077W.

Proteomic databases

MaxQBP36157.
PaxDbP36157.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYKR077W; YKR077W; YKR077W.
GeneID853952.
KEGGsce:YKR077W.

Organism-specific databases

CYGDYKR077w.
SGDS000001785. MSA2.

Phylogenomic databases

eggNOGNOG12793.
OMAHIDEVIP.
OrthoDBEOG7NCVDF.

Enzyme and pathway databases

BioCycYEAST:G3O-32041-MONOMER.

Gene expression databases

GenevestigatorP36157.

Family and domain databases

ProtoNetSearch...

Other

NextBio975359.

Entry information

Entry nameMSA2_YEAST
AccessionPrimary (citable) accession number: P36157
Secondary accession number(s): D6VXD7, Q6Q5M8
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: July 9, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XI

Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD