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P36157

- MSA2_YEAST

UniProt

P36157 - MSA2_YEAST

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Protein
Putative transcriptional activator MSA2
Gene
MSA2, YKR077W
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Biological processi

  1. regulation of transcription involved in G1/S transition of mitotic cell cycle Source: SGD
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Enzyme and pathway databases

BioCyciYEAST:G3O-32041-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative transcriptional activator MSA2
Alternative name(s):
MBF and SBF-associated protein 2
Gene namesi
Name:MSA2
Ordered Locus Names:YKR077W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome XI

Organism-specific databases

CYGDiYKR077w.
SGDiS000001785. MSA2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 363363Putative transcriptional activator MSA2
PRO_0000203223Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei157 – 1571Phosphoserine1 Publication
Modified residuei292 – 2921Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP36157.
PaxDbiP36157.

Expressioni

Gene expression databases

GenevestigatoriP36157.

Interactioni

Subunit structurei

Interacts with transcription complexes SCB-binding factor (SBF) and MCB-binding factor (MBF). Interacts with SWI4.1 Publication

Protein-protein interaction databases

BioGridi34208. 39 interactions.
DIPiDIP-2702N.
IntActiP36157. 7 interactions.
MINTiMINT-1548078.
STRINGi4932.YKR077W.

Structurei

3D structure databases

ProteinModelPortaliP36157.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG12793.
OMAiHIDEVIP.
OrthoDBiEOG7NCVDF.

Sequencei

Sequence statusi: Complete.

P36157-1 [UniParc]FASTAAdd to Basket

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MVYTTPQQQQ RFSSTPQSSH TLIFSPIRAP SMQTPSSLDY QSPSIVVSSS    50
SMKVHGRSSS FGKFSLSIGQ NGKATILGPI NVLPTDTSKM EKPVPKKKPV 100
TSDRVEKTRI LSLLKKMRNK SSTVNKKYSK VPLKSTTSLQ PAATAPSPLV 150
SNIIKPSPKK LASPRTPNAN SNLNLNFTSF QIKTGFTPNL DGILLENFTS 200
PNTTADSQGN SASNIINNNH GSANNTNQFL FNLPLQSSPR QFRSPARLID 250
PLPISDWNTS LLMSPPRTTN FESANNHFNS NFAQASMLRR PSLPHIDEVI 300
PQDSNPANYS DRSDYLSVDQ NANNHNGALS EQTYNNIMKS SMISLPIEKD 350
DATMALRKLV SRE 363
Length:363
Mass (Da):39,862
Last modified:June 1, 1994 - v1
Checksum:iD6E5DA379605650A
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti122 – 1221S → R in AAS56248. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z28302 Genomic DNA. Translation: CAA82156.1.
AY557922 Genomic DNA. Translation: AAS56248.1.
BK006944 Genomic DNA. Translation: DAA09227.1.
PIRiS38154.
RefSeqiNP_013003.1. NM_001179867.1.

Genome annotation databases

EnsemblFungiiYKR077W; YKR077W; YKR077W.
GeneIDi853952.
KEGGisce:YKR077W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z28302 Genomic DNA. Translation: CAA82156.1 .
AY557922 Genomic DNA. Translation: AAS56248.1 .
BK006944 Genomic DNA. Translation: DAA09227.1 .
PIRi S38154.
RefSeqi NP_013003.1. NM_001179867.1.

3D structure databases

ProteinModelPortali P36157.
ModBasei Search...

Protein-protein interaction databases

BioGridi 34208. 39 interactions.
DIPi DIP-2702N.
IntActi P36157. 7 interactions.
MINTi MINT-1548078.
STRINGi 4932.YKR077W.

Proteomic databases

MaxQBi P36157.
PaxDbi P36157.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YKR077W ; YKR077W ; YKR077W .
GeneIDi 853952.
KEGGi sce:YKR077W.

Organism-specific databases

CYGDi YKR077w.
SGDi S000001785. MSA2.

Phylogenomic databases

eggNOGi NOG12793.
OMAi HIDEVIP.
OrthoDBi EOG7NCVDF.

Enzyme and pathway databases

BioCyci YEAST:G3O-32041-MONOMER.

Miscellaneous databases

NextBioi 975359.

Gene expression databases

Genevestigatori P36157.

Family and domain databases

ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete DNA sequence of yeast chromosome XI."
    Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C.
    , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
    Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  6. "The SBF- and MBF-associated protein Msa1 is required for proper timing of G1-specific transcription in Saccharomyces cerevisiae."
    Ashe M., de Bruin R.A.M., Kalashnikova T., McDonald W.H., Yates J.R. III, Wittenberg C.
    J. Biol. Chem. 283:6040-6049(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY, INTERACTION WITH SWI4; SBF AND MBF COMPLEXES.
  7. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
    Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
    Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-157 AND SER-292, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiMSA2_YEAST
AccessioniPrimary (citable) accession number: P36157
Secondary accession number(s): D6VXD7, Q6Q5M8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: July 9, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 861 molecules/cell in log phase SD medium.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XI
    Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

External Data

Dasty 3

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