ID   YK55_YEAST              Reviewed;         307 AA.
AC   P36155; D6VXD5;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   27-MAR-2024, entry version 136.
DE   RecName: Full=Uncharacterized protein YKR075C;
GN   OrderedLocusNames=YKR075C;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7705654; DOI=10.1093/genetics/139.1.95;
RA   di Como C.J., Bose R., Arndt K.T.;
RT   "Overexpression of SIS2, which contains an extremely acidic region,
RT   increases the expression of SWI4, CLN1 and CLN2 in sit4 mutants.";
RL   Genetics 139:95-107(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=8196765; DOI=10.1038/369371a0;
RA   Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V.,
RA   Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P.,
RA   Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L.,
RA   Daignan-Fornier B., del Rey F., Dion C., Domdey H., Duesterhoeft A.,
RA   Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H.,
RA   Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L.,
RA   Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M.,
RA   Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H.,
RA   Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J.,
RA   Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H.,
RA   Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J.,
RA   Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S.,
RA   Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F.,
RA   Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R.,
RA   Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W.,
RA   Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M.,
RA   Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C.,
RA   Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H.,
RA   Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L.,
RA   van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S.,
RA   von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M.,
RA   Becker I., Mewes H.-W.;
RT   "Complete DNA sequence of yeast chromosome XI.";
RL   Nature 369:371-378(1994).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=17322287; DOI=10.1101/gr.6037607;
RA   Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA   Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA   Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA   Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA   LaBaer J.;
RT   "Approaching a complete repository of sequence-verified protein-encoding
RT   clones for Saccharomyces cerevisiae.";
RL   Genome Res. 17:536-543(2007).
RN   [5]
RP   LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX   PubMed=14562106; DOI=10.1038/nature02046;
RA   Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA   O'Shea E.K., Weissman J.S.;
RT   "Global analysis of protein expression in yeast.";
RL   Nature 425:737-741(2003).
CC   -!- MISCELLANEOUS: Present with 1960 molecules/cell in log phase SD medium.
CC       {ECO:0000269|PubMed:14562106}.
CC   -!- SIMILARITY: To yeast YOR062c. {ECO:0000305}.
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DR   EMBL; U01878; AAA79998.1; -; Genomic_DNA.
DR   EMBL; Z28300; CAA82154.1; -; Genomic_DNA.
DR   EMBL; AY557911; AAS56237.1; -; Genomic_DNA.
DR   EMBL; BK006944; DAA09225.1; -; Genomic_DNA.
DR   PIR; S38152; S38152.
DR   RefSeq; NP_013001.1; NM_001179865.1.
DR   AlphaFoldDB; P36155; -.
DR   BioGRID; 34206; 80.
DR   IntAct; P36155; 1.
DR   MINT; P36155; -.
DR   STRING; 4932.YKR075C; -.
DR   iPTMnet; P36155; -.
DR   MaxQB; P36155; -.
DR   PaxDb; 4932-YKR075C; -.
DR   PeptideAtlas; P36155; -.
DR   EnsemblFungi; YKR075C_mRNA; YKR075C; YKR075C.
DR   GeneID; 853950; -.
DR   KEGG; sce:YKR075C; -.
DR   AGR; SGD:S000001783; -.
DR   SGD; S000001783; YKR075C.
DR   VEuPathDB; FungiDB:YKR075C; -.
DR   eggNOG; ENOG502RYV2; Eukaryota.
DR   GeneTree; ENSGT00940000176469; -.
DR   HOGENOM; CLU_058084_1_0_1; -.
DR   InParanoid; P36155; -.
DR   OMA; HHEFNDA; -.
DR   OrthoDB; 2517271at2759; -.
DR   BioCyc; YEAST:G3O-32039-MONOMER; -.
DR   BioGRID-ORCS; 853950; 6 hits in 10 CRISPR screens.
DR   PRO; PR:P36155; -.
DR   Proteomes; UP000002311; Chromosome XI.
DR   RNAct; P36155; Protein.
DR   GO; GO:0005737; C:cytoplasm; HDA:SGD.
DR   GO; GO:0005634; C:nucleus; HDA:SGD.
DR   GO; GO:0005773; C:vacuole; IEA:GOC.
DR   GO; GO:0042149; P:cellular response to glucose starvation; IBA:GO_Central.
DR   GO; GO:0007039; P:protein catabolic process in the vacuole; IBA:GO_Central.
DR   PANTHER; PTHR28051; PROTEIN MTL1-RELATED; 1.
DR   PANTHER; PTHR28051:SF1; PROTEIN MTL1-RELATED; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..307
FT                   /note="Uncharacterized protein YKR075C"
FT                   /id="PRO_0000203222"
FT   REGION          254..278
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        254..271
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   307 AA;  36113 MW;  0DC6D0241DADE1C5 CRC64;
     MTSLDDTIIS YQNIMLLDNM TNYNKPAIDY FHHEFNDASL EISASWTLLL KMRKHKLLRL
     PSCSSEDVLD YNMYLVRLHH CLWRRWSINH YGLQNSKSNP LSINWNKETD VTVLYGPDLT
     NIDSNENEIS PVQNQIDQKQ TKNLKSALKK NTECWVTEEV DEINASIESN DNALVKLEDI
     SCPSSVDSHT SSIFDQHSTC TKISSIDEDS EDLMNEKKEQ FPRKLKFNQA VMKREIDSKG
     TIRESLININ DIQHSRHHRR HHRRHHHHHH QNSSHSDETI KEAHYEFSNY TFGTMEEDIF
     YRNQVVF
//