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P36144 (RL1D1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 102. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribosome biogenesis protein UTP30
Alternative name(s):
U3 snoRNP-associated protein UTP30
Gene names
Name:UTP30
Ordered Locus Names:YKR060W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length274 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Involved in rRNA-processing and ribosome biosynthesis. Ref.8

Subunit structure

Component of the 90S pre-ribosomes. Interacts with FAF1. Ref.4 Ref.7

Subcellular location

Nucleusnucleolus Ref.5.

Miscellaneous

Present with 3060 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the ribosomal protein L1P family. Highly divergent.

Ontologies

Keywords
   Biological processRibosome biogenesis
rRNA processing
   Cellular componentNucleus
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processrRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

ribosomal small subunit biogenesis

Inferred from physical interaction PubMed 21724601. Source: SGD

   Cellular_componentnucleolus

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 274274Ribosome biogenesis protein UTP30
PRO_0000203217

Sequences

Sequence LengthMass (Da)Tools
P36144 [UniParc].

Last modified June 1, 1994. Version 1.
Checksum: 897F2B8C54CE8030

FASTA27431,616
        10         20         30         40         50         60 
MVESNDIIKS GLAEKALKAL ILQCEENPSL KNDKDIHIII NTGKKMGINR DNIPRIIPLT 

        70         80         90        100        110        120 
KYKLFKPRDL NILLITKDPS ALYRETLTKD EHTSELFKEI ISVKNLRRRF KGSKLTQLYK 

       130        140        150        160        170        180 
DFDLVVADYR VHHLLPEVLG SRFYHGSKKL PYMIRMSKEV KLKRQQMVEK CDPIYVRAQL 

       190        200        210        220        230        240 
RSICKNTSYI PNNDNCLSVR VGYIQKHSIP EILQNIQDTI NFLTDKSKRP QGGVIKGGII 

       250        260        270 
SIFVKTSNST SLPIYQFSEA RENQKNEDLS DIKL 

« Hide

References

« Hide 'large scale' references
[1]"Complete DNA sequence of yeast chromosome XI."
Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C. expand/collapse author list , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]"90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors."
Grandi P., Rybin V., Bassler J., Petfalski E., Strauss D., Marzioch M., Schaefer T., Kuster B., Tschochner H., Tollervey D., Gavin A.-C., Hurt E.
Mol. Cell 10:105-115(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION IN THE 90S PRE-RIBOSOME, IDENTIFICATION BY MASS SPECTROMETRY.
[5]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[6]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[7]"Fcf1p and Fcf2p are novel nucleolar Saccharomyces cerevisiae proteins involved in pre-rRNA processing."
Rempola B., Karkusiewicz I., Piekarska I., Rytka J.
Biochem. Biophys. Res. Commun. 346:546-554(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH FAF1.
[8]"The budding yeast rRNA and ribosome biosynthesis (RRB) regulon contains over 200 genes."
Wade C.H., Umbarger M.A., McAlear M.A.
Yeast 23:293-306(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z28285 Genomic DNA. Translation: CAA82139.1.
AY557907 Genomic DNA. Translation: AAS56233.1.
BK006944 Genomic DNA. Translation: DAA09211.1.
PIRS38136.
RefSeqNP_012986.1. NM_001179850.1.

3D structure databases

ProteinModelPortalP36144.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid34191. 56 interactions.
DIPDIP-1926N.
IntActP36144. 12 interactions.
MINTMINT-8285317.
STRING4932.YKR060W.

Proteomic databases

MaxQBP36144.
PaxDbP36144.
PeptideAtlasP36144.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYKR060W; YKR060W; YKR060W.
GeneID853934.
KEGGsce:YKR060W.

Organism-specific databases

CYGDYKR060w.
SGDS000001768. UTP30.

Phylogenomic databases

eggNOGNOG316750.
HOGENOMHOG000248442.
KOK14775.
OMADPSTPYR.
OrthoDBEOG7C8GVC.

Enzyme and pathway databases

BioCycYEAST:G3O-32028-MONOMER.

Gene expression databases

GenevestigatorP36144.

Family and domain databases

InterProIPR023674. Ribosomal_L1-like.
IPR028364. Ribosomal_L1/biogenesis.
[Graphical view]
PfamPF00687. Ribosomal_L1. 1 hit.
[Graphical view]
SUPFAMSSF56808. SSF56808. 1 hit.
ProtoNetSearch...

Other

NextBio975309.

Entry information

Entry nameRL1D1_YEAST
AccessionPrimary (citable) accession number: P36144
Secondary accession number(s): D6VXC1
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: May 14, 2014
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XI

Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries