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P36137 (UIP5_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein UIP5
Alternative name(s):
ULP1-interacting protein 5
Gene names
Name:UIP5
Ordered Locus Names:YKR044W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length443 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Nucleus membrane; Single-pass type I membrane protein.

Miscellaneous

Present with 319 molecules/cell in log phase SD medium.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2727 Potential
Chain28 – 443416Protein UIP5
PRO_0000203212

Regions

Topological domain28 – 398371Perinuclear space Potential
Transmembrane399 – 42022Helical; Potential
Topological domain421 – 44323Cytoplasmic Potential

Sequences

Sequence LengthMass (Da)Tools
P36137 [UniParc].

Last modified June 1, 1994. Version 1.
Checksum: 360A0117AC2667A2

FASTA44350,981
        10         20         30         40         50         60 
MSRDVRAEKL AISLLILSLF LIFQLVAEIY LNNGDQYHTE TSPFTRGRSH VTRVPNHDAS 

        70         80         90        100        110        120 
LSIPFLDKIN QFWHVGGATQ IRNIQSIKLT QDRDQDKHGL VLSNGIGDNT INDFEIVFTF 

       130        140        150        160        170        180 
RISHDPTTQL TGDGMCFAIT PENGFLTQNL QSSYAKKQYM MNSQGVIADN TDLMGFPKNL 

       190        200        210        220        230        240 
PGLFIVLDTY RNQGHDHKEV PFMDVFINVA PESDWYDINS DGELSTSLRL NSRGHIKLKK 

       250        260        270        280        290        300 
NALWNRVTKL RIIYLESISF LKIDVQYAKE GNYWIELFQT TENLYLPKNM HTGQRYIGCS 

       310        320        330        340        350        360 
ALNGQLTETV ELLDVSTSEF HWNDMDASIE DTYDYAKEAE LFLEQEFGEV LDREPDEFTK 

       370        380        390        400        410        420 
WKMIKAQPNI KTGSQSAEQK TSNNPHSRLF KVVLTIWHYS EILLLIMGIY LFSACIRVFQ 

       430        440 
RRFKKIRSRR KRAGSHSVGL LPM 

« Hide

References

« Hide 'large scale' references
[1]"Complete DNA sequence of yeast chromosome XI."
Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C. expand/collapse author list , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]"A global topology map of the Saccharomyces cerevisiae membrane proteome."
Kim H., Melen K., Oesterberg M., von Heijne G.
Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: ATCC 208353 / W303-1A.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z28269 Genomic DNA. Translation: CAA82120.1.
AY723841 Genomic DNA. Translation: AAU09758.1.
BK006944 Genomic DNA. Translation: DAA09196.1.
PIRS38116.
RefSeqNP_012970.3. NM_001179834.3.

3D structure databases

ProteinModelPortalP36137.
SMRP36137. Positions 57-333.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid34176. 15 interactions.
DIPDIP-4845N.
IntActP36137. 1 interaction.
MINTMINT-564407.
STRING4932.YKR044W.

Proteomic databases

PaxDbP36137.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYKR044W; YKR044W; YKR044W.
GeneID853918.
KEGGsce:YKR044W.

Organism-specific databases

CYGDYKR044w.
SGDS000001752. UIP5.

Phylogenomic databases

eggNOGNOG44364.
HOGENOMHOG000154773.
OMAGDNTIND.
OrthoDBEOG76X69V.

Enzyme and pathway databases

BioCycYEAST:G3O-32015-MONOMER.

Gene expression databases

GenevestigatorP36137.

Family and domain databases

Gene3D2.60.120.200. 1 hit.
InterProIPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR005052. Lectin_leg.
[Graphical view]
PANTHERPTHR12223. PTHR12223. 1 hit.
PfamPF03388. Lectin_leg-like. 2 hits.
[Graphical view]
SUPFAMSSF49899. SSF49899. 2 hits.
ProtoNetSearch...

Other

NextBio975264.

Entry information

Entry nameUIP5_YEAST
AccessionPrimary (citable) accession number: P36137
Secondary accession number(s): D6VXA6
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: May 14, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XI

Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD