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Protein

Protein GMH1

Gene

GMH1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • vesicle-mediated transport Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-32006-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein GMH1
Alternative name(s):
GEA1-6 membrane-associated high-copy suppressor protein 1
Gene namesi
Name:GMH1
Synonyms:MSG1
Ordered Locus Names:YKR030W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi

Organism-specific databases

EuPathDBiFungiDB:YKR030W
SGDiS000001738 GMH1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini2 – 89CytoplasmicSequence analysisAdd BLAST88
Transmembranei90 – 110HelicalSequence analysisAdd BLAST21
Topological domaini111 – 134LumenalSequence analysisAdd BLAST24
Transmembranei135 – 155HelicalSequence analysisAdd BLAST21
Topological domaini156 – 175CytoplasmicSequence analysisAdd BLAST20
Transmembranei176 – 196HelicalSequence analysisAdd BLAST21
Topological domaini197 – 216LumenalSequence analysisAdd BLAST20
Transmembranei217 – 237HelicalSequence analysisAdd BLAST21
Topological domaini238 – 242CytoplasmicSequence analysis5
Transmembranei243 – 263HelicalSequence analysisAdd BLAST21
Topological domaini264 – 273LumenalSequence analysis10

Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources
ChainiPRO_00002032052 – 273Protein GMH1Add BLAST272

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiP36125
PRIDEiP36125

PTM databases

iPTMnetiP36125

Interactioni

Subunit structurei

Interacts with GEA1 and GEA2.1 Publication

Protein-protein interaction databases

BioGridi34163, 88 interactors
DIPiDIP-2023N
IntActiP36125, 9 interactors
MINTiP36125
STRINGi4932.YKR030W

Structurei

3D structure databases

ProteinModelPortaliP36125
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the unc-50 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00390000018553
HOGENOMiHOG000193563
InParanoidiP36125
OMAiHTNAFFP
OrthoDBiEOG092C50WH

Family and domain databases

InterProiView protein in InterPro
IPR007881 UNC-50
PANTHERiPTHR12841 PTHR12841, 1 hit
PfamiView protein in Pfam
PF05216 UNC-50, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P36125-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYLPTYSND LPAGPQGQRR RNNGNENDAR QGYGQQSVPM VIRRLFKTPK
60 70 80 90 100
NLDLETASWE MFHLIFHPRK AYRSIYYQRQ TKNQWARDDP SFFIFQIALI
110 120 130 140 150
SLSSIIWSIY NSGFNNDSDM GALSIIGHFF KSLVMMVILD FFIFGFIMAT
160 170 180 190 200
IFYLLLNRSH FKFKSSQNSV VEWAYCFDVH CNSFLIILLC LYFIQFLLLP
210 220 230 240 250
IINLQNWISL LIGNSLYCFA IGHYFILTFY GYNQLPFLKN LNFILLPTLG
260 270
LSIIYLISLF GIDLSKKLSF YNY
Length:273
Mass (Da):31,993
Last modified:June 1, 1994 - v1
Checksum:i94E991416D7630F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z28255 Genomic DNA Translation: CAA82102.1
BK006944 Genomic DNA Translation: DAA09185.1
PIRiS38102
RefSeqiNP_012955.1, NM_001179820.1

Genome annotation databases

EnsemblFungiiYKR030W; YKR030W; YKR030W
GeneIDi853901
KEGGisce:YKR030W

Entry informationi

Entry nameiGMH1_YEAST
AccessioniPrimary (citable) accession number: P36125
Secondary accession number(s): D6VX95
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: May 23, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XI
    Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

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