Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein BCH2

Gene

BCH2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Member of the CHS5-ARF1P-binding proteins (CHAPS) which mediates export of specific cargo proteins, including chitin synthase CHS3.3 Publications

Miscellaneous

Present with 2540 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

  • cellular bud site selection Source: GO_Central
  • fungal-type cell wall chitin biosynthetic process Source: SGD
  • Golgi to plasma membrane transport Source: SGD
  • protein transport Source: UniProtKB-KW

Keywordsi

Biological processProtein transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-32003-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein BCH2
Alternative name(s):
BUD7 and CHS6 homolog 2
Gene namesi
Name:BCH2
Synonyms:FMP50
Ordered Locus Names:YKR027W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XI

Organism-specific databases

EuPathDBiFungiDB:YKR027W.
SGDiS000001735. BCH2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002032041 – 765Protein BCH2Add BLAST765

Proteomic databases

MaxQBiP36122.
PRIDEiP36122.

PTM databases

iPTMnetiP36122.

Interactioni

Subunit structurei

Component of the CHS5/6 complex composed of the 4 CHAPS proteins BCH1, BCH2, BUD7, and CHS6 as well as at least CHS5 and GTP-bound ARF1. The complex interacts with the cargo protein CHS3.3 Publications

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi34160. 173 interactors.
IntActiP36122. 9 interactors.
MINTiMINT-600256.
STRINGi4932.YKR027W.

Structurei

3D structure databases

ProteinModelPortaliP36122.
SMRiP36122.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni735 – 765CHS5-bindingAdd BLAST31

Sequence similaritiesi

Belongs to the CHAPS family.Curated

Phylogenomic databases

GeneTreeiENSGT00530000065203.
HOGENOMiHOG000095187.
InParanoidiP36122.
KOiK19880.
OMAiRKSTWGR.
OrthoDBiEOG092C0PJW.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiView protein in InterPro
IPR015374. ChAPs.
IPR011990. TPR-like_helical_dom_sf.
PfamiView protein in Pfam
PF09295. ChAPs. 2 hits.
SUPFAMiSSF48452. SSF48452. 1 hit.

Sequencei

Sequence statusi: Complete.

P36122-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFLWGSTKS KKGKNKKAAG SLPSGVVPQQ RVKPTRKNVP IDYPRTLEKV
60 70 80 90 100
HGESLIFRTS LLSELVSTGK SGIGPPDLIH CTELDKFHDE KIGEFFYITG
110 120 130 140 150
IDASSVSMPI AFLKLIKWND GKKLKSASLK NDDITTYCTF NIFQKLDIRL
160 170 180 190 200
RYESEDVYQV NIVDCLNGNN EIPLSDLIWE ETFVSCCIRS VIINSDFERK
210 220 230 240 250
IPGLVELPFV FENRCASDYK RVIDSLCKFL PRFLECGWDS TKSVYATILN
260 270 280 290 300
NYLTESLLVF LSITPEFITD YAIQVLDNLM TNDPSNSRYY AIVIISIMER
310 320 330 340 350
SNDRDVEMIK RIHEILDLLL PVLYGLPSDE PYISDLINCI TDVLSIQARF
360 370 380 390 400
LLNNNDYELS LSISTLATNL SSDNFESWYL LSKGYIFSQQ YDKALLSINS
410 420 430 440 450
MPCLAEYDIV KQAQINAFKF YMNYYKAPLC HSREHCTMTS HELNHLMNIM
460 470 480 490 500
HYENELELKT IIFGRTVMPN ESKYGCIEEI WNKSCLELGP ICGPQSDNLI
510 520 530 540 550
NFVSQQEVNT VGDMLLLKRS KETRQESWFI KQVRLLLMEL VARIGWNALL
560 570 580 590 600
QLRSDVFVME SKFKMIESSD KLSTELRQKR LCQRWFDAMF LDVYEDLSIS
610 620 630 640 650
TSSQENKATA KYSGLEWELL GLTLLRVSDL PDAVACLRTS ILARFDPISC
660 670 680 690 700
HHLLNFYLTM DFNDEFMRRF DVDIILDLLV KLISFRIRFY DRFQIFSLQV
710 720 730 740 750
LRKLEGQLGS EIIKNKIINS PYGQAGITSV IDYMLECLSK NRNEACLAYE
760
RPLPDLPSTI KPLAD
Length:765
Mass (Da):88,044
Last modified:June 1, 1994 - v1
Checksum:i53A4A700682287E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z28252 Genomic DNA. Translation: CAA82099.1.
BK006944 Genomic DNA. Translation: DAA09182.1.
PIRiS38099.
RefSeqiNP_012952.3. NM_001179817.3.

Genome annotation databases

EnsemblFungiiYKR027W; YKR027W; YKR027W.
GeneIDi853898.
KEGGisce:YKR027W.

Similar proteinsi

Entry informationi

Entry nameiBCH2_YEAST
AccessioniPrimary (citable) accession number: P36122
Secondary accession number(s): D6VX92
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: November 22, 2017
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XI
    Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names