P36103 (YKC3_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein YKL023W

Gene names

Ordered Locus Names:

YKL023W

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	277 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Cytoplasm Ref.3.
Miscellaneous	Present with 1730 molecules/cell in log phase SD medium.

Ontologies

Keywords
Cellular component	Cytoplasm
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from direct assay Ref.3. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 277	277	Uncharacterized protein YKL023W		PRO_0000203189
Amino acid modifications
	Modified residue	14	1	Phosphoserine Ref.5
	Modified residue	47	1	Phosphoserine Ref.5
Experimental info
	Sequence conflict	25 – 26	2	QQ → HE in CAA81858. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P36103 [UniParc]. Last modified September 21, 2011. Version 2. Checksum: 01EAC7E4439171DB	FASTA	277	32,293
	10 20 30 40 50 60 MNKEELLGFL LDDSIDSQKR CVTDQQAYSN WLKNDNDERT AHEESSSQST IAALNKKKQT 70 80 90 100 110 120 EAAQEDIEEL LNGLEGIIGG ADPRNLKSKS KRKTKKGGSK PREENVNTEK HIVMLEVEDF 130 140 150 160 170 180 SDMSTHEDVN GASPSPNLDR SKKNEKRRKN AKELSYDELK DKLEVTTRKS RLECKDLKKK 190 200 210 220 230 240 VHGLERRNLE LEQRLEELKI ENQTLIEINN KLLKNTNEDE INKSQRNKEK DRKRRERRTA 250 260 270 RRKDERKQEK KQEKKQDNKT SQSFPSSTDM NGQPIEF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete DNA sequence of yeast chromosome XI." Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C. , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W. Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[2]	Saccharomyces Genome Database Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION, SEQUENCE REVISION TO 25-26. Strain: ATCC 204508 / S288c.
[3]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[4]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]	"A multidimensional chromatography technology for in-depth phosphoproteome analysis." Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H. Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-14 AND SER-47, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z28023 Genomic DNA. Translation: CAA81858.1. BK006944 Genomic DNA. Translation: DAA09132.2.
PIR	S37840.
RefSeq	NP_012902.4. NM_001179589.4.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-1760N.
IntAct	P36103. 4 interactions.
MINT	MINT-412213.
STRING	4932.YKL023W.
Proteomic databases
PaxDb	P36103.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YKL023W; YKL023W; YKL023W.
GeneID	853845.
KEGG	sce:YKL021C. sce:YKL023W.
Organism-specific databases
CYGD	YKL023w.
SGD	S000001506. YKL023W.
Phylogenomic databases
KO	K14830.
Gene expression databases
Genevestigator	P36103.
GermOnline	YKL023W. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...
Other
NextBio	975064.

Entry information

Entry name

YKC3_YEAST

Accession

Primary (citable) accession number: P36103
Secondary accession number(s): D6VXR2

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 1, 1994
Last sequence update:	September 21, 2011
Last modified:	April 3, 2013
This is version 77 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program