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P36093

- PHD1_YEAST

UniProt

P36093 - PHD1_YEAST

Protein

Putative transcription factor PHD1

Gene

PHD1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 107 (01 Oct 2014)
      Sequence version 1 (01 Jun 1994)
      Previous versions | rss
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    Functioni

    Putative transcription factor that functions in pseudohyphal growth.

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi220 – 24122H-T-H motifPROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. sequence-specific DNA binding transcription factor activity Source: SGD

    GO - Biological processi

    1. positive regulation of transcription from RNA polymerase II promoter Source: SGD
    2. pseudohyphal growth Source: SGD
    3. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31844-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative transcription factor PHD1
    Gene namesi
    Name:PHD1
    Ordered Locus Names:YKL043W
    ORF Names:YKL256
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome XI

    Organism-specific databases

    CYGDiYKL043w.
    SGDiS000001526. PHD1.

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: SGD

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 366366Putative transcription factor PHD1PRO_0000058377Add
    BLAST

    Proteomic databases

    MaxQBiP36093.
    PaxDbiP36093.

    Expressioni

    Gene expression databases

    GenevestigatoriP36093.

    Interactioni

    Protein-protein interaction databases

    BioGridi34089. 39 interactions.
    DIPiDIP-4868N.
    IntActiP36093. 2 interactions.
    MINTiMINT-495993.

    Structurei

    3D structure databases

    ProteinModelPortaliP36093.
    SMRiP36093. Positions 186-281.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini186 – 292107HTH APSES-typePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the EFG1/PHD1/stuA family.Curated
    Contains 1 HTH APSES-type DNA-binding domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG41372.
    GeneTreeiENSGT00530000067611.
    OMAiHEIATEI.
    OrthoDBiEOG7K9KD5.

    Family and domain databases

    Gene3Di3.10.260.10. 1 hit.
    InterProiIPR018004. KilA_N/APSES_HTH.
    IPR003163. Tscrpt_reg_HTH_APSES-type.
    [Graphical view]
    PfamiPF04383. KilA-N. 1 hit.
    [Graphical view]
    SUPFAMiSSF54616. SSF54616. 1 hit.
    PROSITEiPS51299. HTH_APSES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P36093-1 [UniParc]FASTAAdd to Basket

    « Hide

    MYHVPEMRLH YPLVNTQSNA AITPTRSYDN TLPSFNELSH QSTINLPFVQ    50
    RETPNAYANV AQLATSPTQA KSGYYCRYYA VPFPTYPQQP QSPYQQAVLP 100
    YATIPNSNFQ PSSFPVMAVM PPEVQFDGSF LNTLHPHTEL PPIIQNTNDT 150
    SVARPNNLKS IAAASPTVTA TTRTPGVSST SVLKPRVITT MWEDENTICY 200
    QVEANGISVV RRADNNMING TKLLNVTKMT RGRRDGILRS EKVREVVKIG 250
    SMHLKGVWIP FERAYILAQR EQILDHLYPL FVKDIESIVD ARKPSNKASL 300
    TPKSSPAPIK QEPSDNKHEI ATEIKPKSID ALSNGASTQG AGELPHLKIN 350
    HIDTEAQTSR AKNELS 366
    Length:366
    Mass (Da):40,646
    Last modified:June 1, 1994 - v1
    Checksum:i22B6FA0D505D8654
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U05241 Unassigned DNA. Translation: AAA18358.1.
    X71621 Genomic DNA. Translation: CAA50629.1.
    Z28043 Genomic DNA. Translation: CAA81878.1.
    AY557923 Genomic DNA. Translation: AAS56249.1.
    AY949939 Genomic DNA. Translation: AAY27341.1.
    AY949940 Genomic DNA. Translation: AAY27342.1.
    AY949941 Genomic DNA. Translation: AAY27343.1.
    AY949942 Genomic DNA. Translation: AAY27344.1.
    AY949943 Genomic DNA. Translation: AAY27345.1.
    AY949944 Genomic DNA. Translation: AAY27346.1.
    AY949945 Genomic DNA. Translation: AAY27347.1.
    AY949946 Genomic DNA. Translation: AAY27348.1.
    AY949947 Genomic DNA. Translation: AAY27349.1.
    AY949948 Genomic DNA. Translation: AAY27350.1.
    BK006944 Genomic DNA. Translation: DAA09113.1.
    PIRiS37864.
    RefSeqiNP_012881.1. NM_001179609.1.

    Genome annotation databases

    EnsemblFungiiYKL043W; YKL043W; YKL043W.
    GeneIDi853823.
    KEGGisce:YKL043W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U05241 Unassigned DNA. Translation: AAA18358.1 .
    X71621 Genomic DNA. Translation: CAA50629.1 .
    Z28043 Genomic DNA. Translation: CAA81878.1 .
    AY557923 Genomic DNA. Translation: AAS56249.1 .
    AY949939 Genomic DNA. Translation: AAY27341.1 .
    AY949940 Genomic DNA. Translation: AAY27342.1 .
    AY949941 Genomic DNA. Translation: AAY27343.1 .
    AY949942 Genomic DNA. Translation: AAY27344.1 .
    AY949943 Genomic DNA. Translation: AAY27345.1 .
    AY949944 Genomic DNA. Translation: AAY27346.1 .
    AY949945 Genomic DNA. Translation: AAY27347.1 .
    AY949946 Genomic DNA. Translation: AAY27348.1 .
    AY949947 Genomic DNA. Translation: AAY27349.1 .
    AY949948 Genomic DNA. Translation: AAY27350.1 .
    BK006944 Genomic DNA. Translation: DAA09113.1 .
    PIRi S37864.
    RefSeqi NP_012881.1. NM_001179609.1.

    3D structure databases

    ProteinModelPortali P36093.
    SMRi P36093. Positions 186-281.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 34089. 39 interactions.
    DIPi DIP-4868N.
    IntActi P36093. 2 interactions.
    MINTi MINT-495993.

    Proteomic databases

    MaxQBi P36093.
    PaxDbi P36093.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YKL043W ; YKL043W ; YKL043W .
    GeneIDi 853823.
    KEGGi sce:YKL043W.

    Organism-specific databases

    CYGDi YKL043w.
    SGDi S000001526. PHD1.

    Phylogenomic databases

    eggNOGi NOG41372.
    GeneTreei ENSGT00530000067611.
    OMAi HEIATEI.
    OrthoDBi EOG7K9KD5.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31844-MONOMER.

    Miscellaneous databases

    NextBioi 975008.

    Gene expression databases

    Genevestigatori P36093.

    Family and domain databases

    Gene3Di 3.10.260.10. 1 hit.
    InterProi IPR018004. KilA_N/APSES_HTH.
    IPR003163. Tscrpt_reg_HTH_APSES-type.
    [Graphical view ]
    Pfami PF04383. KilA-N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54616. SSF54616. 1 hit.
    PROSITEi PS51299. HTH_APSES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Induction of pseudohyphal growth by overexpression of PHD1, a Saccharomyces cerevisiae gene related to transcriptional regulators of fungal development."
      Gimeno C.J., Fink G.R.
      Mol. Cell. Biol. 14:2100-2112(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: S288c / YPH1.
    2. "The sequence of a 17.5 kb DNA fragment on the left arm of yeast chromosome XI identifies the protein kinase gene ELM1, the DNA primase gene PRI2, a new gene encoding a putative histone and seven new open reading frames."
      Purnelle B., Tettelin H., van Dyck L., Skala J., Goffeau A.
      Yeast 9:1379-1384(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. "Complete DNA sequence of yeast chromosome XI."
      Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C.
      , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
      Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    5. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    6. "Population structure of the wine yeast Saccharomyces cerevisiae."
      Townsend J.P., Aa E., Taylor J.W.
      Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 76625 / YPH499, YPS396, YPS400, YPS598, YPS600, YPS602, YPS604, YPS606, YPS608 and YPS610.
    7. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiPHD1_YEAST
    AccessioniPrimary (citable) accession number: P36093
    Secondary accession number(s): D6VXP3, Q2VQ88
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 1, 1994
    Last sequence update: June 1, 1994
    Last modified: October 1, 2014
    This is version 107 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 1420 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome XI
      Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

    External Data

    Dasty 3