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P36093 (PHD1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 105. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative transcription factor PHD1
Gene names
Name:PHD1
Ordered Locus Names:YKL043W
ORF Names:YKL256
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length366 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Putative transcription factor that functions in pseudohyphal growth.

Subcellular location

Nucleus.

Miscellaneous

Present with 1420 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the EFG1/PHD1/stuA family.

Contains 1 HTH APSES-type DNA-binding domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 366366Putative transcription factor PHD1
PRO_0000058377

Regions

Domain186 – 292107HTH APSES-type
DNA binding220 – 24122H-T-H motif By similarity

Sequences

Sequence LengthMass (Da)Tools
P36093 [UniParc].

Last modified June 1, 1994. Version 1.
Checksum: 22B6FA0D505D8654

FASTA36640,646
        10         20         30         40         50         60 
MYHVPEMRLH YPLVNTQSNA AITPTRSYDN TLPSFNELSH QSTINLPFVQ RETPNAYANV 

        70         80         90        100        110        120 
AQLATSPTQA KSGYYCRYYA VPFPTYPQQP QSPYQQAVLP YATIPNSNFQ PSSFPVMAVM 

       130        140        150        160        170        180 
PPEVQFDGSF LNTLHPHTEL PPIIQNTNDT SVARPNNLKS IAAASPTVTA TTRTPGVSST 

       190        200        210        220        230        240 
SVLKPRVITT MWEDENTICY QVEANGISVV RRADNNMING TKLLNVTKMT RGRRDGILRS 

       250        260        270        280        290        300 
EKVREVVKIG SMHLKGVWIP FERAYILAQR EQILDHLYPL FVKDIESIVD ARKPSNKASL 

       310        320        330        340        350        360 
TPKSSPAPIK QEPSDNKHEI ATEIKPKSID ALSNGASTQG AGELPHLKIN HIDTEAQTSR 


AKNELS 

« Hide

References

« Hide 'large scale' references
[1]"Induction of pseudohyphal growth by overexpression of PHD1, a Saccharomyces cerevisiae gene related to transcriptional regulators of fungal development."
Gimeno C.J., Fink G.R.
Mol. Cell. Biol. 14:2100-2112(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: S288c / YPH1.
[2]"The sequence of a 17.5 kb DNA fragment on the left arm of yeast chromosome XI identifies the protein kinase gene ELM1, the DNA primase gene PRI2, a new gene encoding a putative histone and seven new open reading frames."
Purnelle B., Tettelin H., van Dyck L., Skala J., Goffeau A.
Yeast 9:1379-1384(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"Complete DNA sequence of yeast chromosome XI."
Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C. expand/collapse author list , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[5]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[6]"Population structure of the wine yeast Saccharomyces cerevisiae."
Townsend J.P., Aa E., Taylor J.W.
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 76625 / YPH499, YPS396, YPS400, YPS598, YPS600, YPS602, YPS604, YPS606, YPS608 and YPS610.
[7]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U05241 Unassigned DNA. Translation: AAA18358.1.
X71621 Genomic DNA. Translation: CAA50629.1.
Z28043 Genomic DNA. Translation: CAA81878.1.
AY557923 Genomic DNA. Translation: AAS56249.1.
AY949939 Genomic DNA. Translation: AAY27341.1.
AY949940 Genomic DNA. Translation: AAY27342.1.
AY949941 Genomic DNA. Translation: AAY27343.1.
AY949942 Genomic DNA. Translation: AAY27344.1.
AY949943 Genomic DNA. Translation: AAY27345.1.
AY949944 Genomic DNA. Translation: AAY27346.1.
AY949945 Genomic DNA. Translation: AAY27347.1.
AY949946 Genomic DNA. Translation: AAY27348.1.
AY949947 Genomic DNA. Translation: AAY27349.1.
AY949948 Genomic DNA. Translation: AAY27350.1.
BK006944 Genomic DNA. Translation: DAA09113.1.
PIRS37864.
RefSeqNP_012881.1. NM_001179609.1.

3D structure databases

ProteinModelPortalP36093.
SMRP36093. Positions 186-281.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid34089. 39 interactions.
DIPDIP-4868N.
IntActP36093. 2 interactions.
MINTMINT-495993.

Proteomic databases

PaxDbP36093.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYKL043W; YKL043W; YKL043W.
GeneID853823.
KEGGsce:YKL043W.

Organism-specific databases

CYGDYKL043w.
SGDS000001526. PHD1.

Phylogenomic databases

eggNOGNOG41372.
GeneTreeENSGT00530000067611.
OrthoDBEOG7K9KD5.

Enzyme and pathway databases

BioCycYEAST:G3O-31844-MONOMER.

Gene expression databases

GenevestigatorP36093.

Family and domain databases

Gene3D3.10.260.10. 1 hit.
InterProIPR018004. KilA_N/APSES_HTH.
IPR003163. Tscrpt_reg_HTH_APSES-type.
[Graphical view]
PfamPF04383. KilA-N. 1 hit.
[Graphical view]
SUPFAMSSF54616. SSF54616. 1 hit.
PROSITEPS51299. HTH_APSES. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio975008.

Entry information

Entry namePHD1_YEAST
AccessionPrimary (citable) accession number: P36093
Secondary accession number(s): D6VXP3, Q2VQ88
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: April 16, 2014
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XI

Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families