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P36086

- YKH1_YEAST

UniProt

P36086 - YKH1_YEAST

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Protein
Uncharacterized oxidoreductase YKL071W
Gene
YKL071W
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei148 – 1481Substrate By similarity
Active sitei164 – 1641Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi13 – 197NAD or NADP By similarity

GO - Molecular functioni

  1. oxidoreductase activity Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Oxidoreductase

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31867-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized oxidoreductase YKL071W
    Gene namesi
    Ordered Locus Names:YKL071W
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome XI

    Organism-specific databases

    CYGDiYKL071w.
    SGDiS000001554. YKL071W.

    Subcellular locationi

    Cytoplasm 1 Publication

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 256256Uncharacterized oxidoreductase YKL071W
    PRO_0000203171Add
    BLAST

    Proteomic databases

    PaxDbiP36086.

    Expressioni

    Gene expression databases

    GenevestigatoriP36086.

    Interactioni

    Protein-protein interaction databases

    BioGridi34061. 8 interactions.
    IntActiP36086. 3 interactions.
    MINTiMINT-4492693.
    STRINGi4932.YKL071W.

    Structurei

    3D structure databases

    ProteinModelPortaliP36086.
    SMRiP36086. Positions 10-232.

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1028.
    GeneTreeiENSGT00510000048108.
    OMAiDIFIACS.
    OrthoDBiEOG72C59W.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    InterProiIPR002347. Glc/ribitol_DH.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PRINTSiPR00081. GDHRDH.

    Sequencei

    Sequence statusi: Complete.

    P36086-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNTSSRITYF IIGGSRGIGF NLVKILSAST GNTVITSIRG SPSLPKNKQV    50
    EDLAKIRKNI HIVQLDLTKD ESIGNIADEI KKTPFFLGID IFIACSAVSD 100
    SYYKVLETPK SVWLNHYSTN ALGPILALQK VYPLLLLKKT RKIFFISSVA 150
    GSINAFVPLS VSAYGQSKAA LNYAVKTLSF ELKPEGFTVV AFHPGMVSTD 200
    MGQYGLDHFK EKNIDISGVN IITPEESASA LIDVFRKILP EDNGKFFNYD 250
    GSEGVF 256
    Length:256
    Mass (Da):28,039
    Last modified:June 1, 1994 - v1
    Checksum:iB29F3A3733E3208C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X75780 Genomic DNA. Translation: CAA53403.1.
    Z28071 Genomic DNA. Translation: CAA81908.1.
    AY692597 Genomic DNA. Translation: AAT92616.1.
    BK006944 Genomic DNA. Translation: DAA09085.1.
    PIRiS37893.
    RefSeqiNP_012852.1. NM_001179637.1.

    Genome annotation databases

    EnsemblFungiiYKL071W; YKL071W; YKL071W.
    GeneIDi853792.
    KEGGisce:YKL071W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X75780 Genomic DNA. Translation: CAA53403.1 .
    Z28071 Genomic DNA. Translation: CAA81908.1 .
    AY692597 Genomic DNA. Translation: AAT92616.1 .
    BK006944 Genomic DNA. Translation: DAA09085.1 .
    PIRi S37893.
    RefSeqi NP_012852.1. NM_001179637.1.

    3D structure databases

    ProteinModelPortali P36086.
    SMRi P36086. Positions 10-232.
    ModBasei Search...

    Protein-protein interaction databases

    BioGridi 34061. 8 interactions.
    IntActi P36086. 3 interactions.
    MINTi MINT-4492693.
    STRINGi 4932.YKL071W.

    Proteomic databases

    PaxDbi P36086.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YKL071W ; YKL071W ; YKL071W .
    GeneIDi 853792.
    KEGGi sce:YKL071W.

    Organism-specific databases

    CYGDi YKL071w.
    SGDi S000001554. YKL071W.

    Phylogenomic databases

    eggNOGi COG1028.
    GeneTreei ENSGT00510000048108.
    OMAi DIFIACS.
    OrthoDBi EOG72C59W.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31867-MONOMER.

    Miscellaneous databases

    NextBioi 974926.

    Gene expression databases

    Genevestigatori P36086.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    InterProi IPR002347. Glc/ribitol_DH.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    PRINTSi PR00081. GDHRDH.
    ProtoNeti Search...

    Publicationsi

    « Hide 'large scale' publications
    1. "Sequence of a 20.7 kb region of yeast chromosome XI includes the NUP100 gene, an open reading frame (ORF) possibly representing a nucleoside diphosphate kinase gene, tRNAs for His, Val and Trp in addition to seven ORFs with weak or no significant similarity to known proteins."
      Rasmussen S.W.
      Yeast 10:S69-S74(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. "Complete DNA sequence of yeast chromosome XI."
      Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C.
      , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
      Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    5. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiYKH1_YEAST
    AccessioniPrimary (citable) accession number: P36086
    Secondary accession number(s): D6VXL5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 1, 1994
    Last sequence update: June 1, 1994
    Last modified: May 14, 2014
    This is version 98 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome XI
      Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

    External Data

    Dasty 3

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