Reviewed, UniProtKB/Swiss-Prot P36068 (YKN0_YEAST)

Names and origin

Protein names

Recommended name:
    Uncharacterized protein YKL130C

Gene names

Ordered Locus Names:

YKL130C

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	246 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Miscellaneous

Present with 4070 molecules/cell in log phase SD medium. Ref.3

Ontologies

Keywords
PTM	Phosphoprotein
Technical term	3D-structure Complete proteome
Gene Ontology (GO)
Biological process	intracellular mRNA localization Inferred from direct assay. Source: SGD mating type switching Inferred from mutant phenotype. Source: SGD
Cellular component	cellular bud tip Inferred from direct assay. Source: SGD cytoplasm Inferred from direct assay. Source: SGD
Molecular function	mRNA binding Inferred from direct assay. Source: SGD protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
	P38272	1	EBI-26866,EBI-21600
AUS1	Q08409	1	EBI-26866,EBI-35723
MYO4	P32492	1	EBI-26866,EBI-11681
SRP1	Q02821	1	EBI-26866,EBI-1797
UBX6	P47049	1	EBI-26866,EBI-25866

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 246

246

Uncharacterized protein YKL130C

PRO_0000203151

Amino acid modifications

Modified residue

166

1

Phosphoserine Ref.4

Secondary structure

1

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246

Helix Strand Turn

Details...

Helix

13 – 42

30

Helix

46 – 48

3

Helix

49 – 71

23

Helix

74 – 77

4

Turn

86 – 88

3

Helix

92 – 118

27

Helix

120 – 129

10

Helix

132 – 134

3

Helix

138 – 161

24

Helix

167 – 169

3

Helix

172 – 179

8

Helix

205 – 235

31

Sequences

	Sequence		Length	Mass (Da)
	P36068-1 [UniParc]. Last modified June 1, 1994. Version 1. Checksum: 5514B374655EFDBB	FASTA	246	28,251
	10 20 30 40 50 60 MSKDKDIKVT PGTCELVEQI LALLSRYLSS YIHVLNKFIS HLRRVATLRF ERTTLIKFVK 70 80 90 100 110 120 KLRFYNDCVL SYNASEFINE GKNELDPEAD SFDKVILPIA SMFVKCVETF DLLNYYLTQS 130 140 150 160 170 180 LQKEILSKTL NEDLTLTAES ILAIDDTYNH FVKFSQWMIE SLRIGSNLLD LEVVQFAIKC 190 200 210 220 230 240 ADEDGTNIGE TDNIFLQEIL PVNSEEEFQT LSAAWHSILD GKLSALDEEF DVVATKWHDK FGKLKN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete DNA sequence of yeast chromosome XI." Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C. , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W. Nature 369:371-378(1994) [PubMed: 8196765] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[2]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[3]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[4]	"Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases." Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H. Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007) [PubMed: 17563356] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-166, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBLGenBankDDBJ

Z28130 Genomic DNA. Translation: CAA81971.1.
AY557902 Genomic DNA. Translation: AAS56228.1.

PIR

S37959.

RefSeq

NP_012792.1.

3D structure databases

PDBPDBe

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1XLY	X-ray	1.95	A/B	6-239	[»]

ModBase

Search...

Protein-protein interaction databases

DIP

DIP:1206N.

IntAct

P36068. 32 interactions.

Proteomic databases

PeptideAtlas

P36068.

Genome annotation databases

Ensembl

YKL130C. Saccharomyces cerevisiae. [Contig view]

GeneID

853728.

GenomeReviews

Gene locus YKL130C in contig Y13137_GR.

KEGG

sce:YKL130C.

NMPDR

fig|4932.3.peg.3773.

Organism-specific databases

CYGD

YKL130c.

SGD

S000001613. SHE2.

Yeast-GFP

Search...

Phylogenomic databases

HOGENOM

P36068.

OMA

P36068. ETDNIFL.

Gene expression databases

GermOnline

YKL130C. Saccharomyces cerevisiae.

Family and domain databases

ProtoNet

Search...

Other Resources

NextBio

974761.

Entry information

Entry name

YKN0_YEAST

Accession

Primary (citable) accession number: P36068

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 1, 1994
Last sequence update:	June 1, 1994
Last modified:	June 16, 2009
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)