P36059 (YKP1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein YKL151C

Gene names

Ordered Locus Names:	YKL151C
ORF Names:	YKL606

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	337 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Cytoplasm Ref.5.
Miscellaneous	Present with 3870 molecules/cell in log phase SD medium. Ref.6
Sequence similarities	Contains 1 YjeF C-terminal domain.

Ontologies

Keywords
Cellular component	Cytoplasm
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	nicotinamide nucleotide metabolic process Inferred from direct assay. Source: SGD
Cellular component	cytoplasm Inferred from direct assay Ref.5. Source: SGD
Molecular function	ATP-dependent NAD(P)H-hydrate dehydratase activity Inferred from direct assay. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 337	337	Uncharacterized protein YKL151C		PRO_0000119053
Regions
	Domain	11 – 335	325	YjeF C-terminal
Amino acid modifications
	Modified residue	6	1	Phosphoserine Ref.7
Experimental info
	Sequence conflict	182	1	N → D in AAS56241. Ref.4

Sequences

	Sequence		Length	Mass (Da)
	P36059 [UniParc]. Last modified June 1, 1994. Version 1. Checksum: 472C46DB6956244E	FASTA	337	37,357
	10 20 30 40 50 60 MLAELSHREL IKLAQKRCIP PLLPKFHKGQ SGGRVCIIGG CEDYTGAPYF SANATALMGC 70 80 90 100 110 120 DLTHVICEYN AGTVIKSYTP NLMVHPYLRM SNTKLDVDMD EQRKKINSLL DRIHVVVIGP 130 140 150 160 170 180 GLGRDPLMLK SIKDIIRYIL EKHEGKIPLV IDADGLFLVT QDSEVKEMLK SYPKGRVILT 190 200 210 220 230 240 PNVVEFKRLC DAIGKKGDSH SEMGSLIAQE LNCIVVEKGQ SDKIFSPDSE KDMLTNSEEG 250 260 270 280 290 300 SNKRVGGQGD TLTGAISCML AFSRAMYDFK ICEQEEKGES SNDKPLKNWV DYAMLSCYAG 310 320 330 CTITRECSRL GFKAKGRAMQ TTDLNDRVGE VFAKLFG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"DNA sequencing of a 36.2 kb fragment located between the FAS1 and LAP loci of chromosome XI of Saccharomyces cerevisiae." Vandenbol M., Bolle P.-A., Dion C., Portetelle D., Hilger F. Yeast 10:S35-S40(1994) [PubMed: 8091859] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[2]	"Complete DNA sequence of yeast chromosome XI." Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C. , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W. Nature 369:371-378(1994) [PubMed: 8196765] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[3]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[4]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[5]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed: 14562095] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[6]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[7]	"A multidimensional chromatography technology for in-depth phosphoproteome analysis." Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H. Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-6, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z26877 Genomic DNA. Translation: CAA81502.1. Z28151 Genomic DNA. Translation: CAA81992.1. AY557915 Genomic DNA. Translation: AAS56241.1. BK006944 Genomic DNA. Translation: DAA09012.1.
PIR	S37799.
RefSeq	NP_012771.1. NM_001179717.1.
3D structure databases
ProteinModelPortal	P36059.
SMR	P36059. Positions 11-335.
ModBase	Search...
Protein-protein interaction databases
IntAct	P36059. 2 interactions.
MINT	MINT-2493845.
STRING	P36059.
Proteomic databases
PeptideAtlas	P36059.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YKL151C; YKL151C; YKL151C.
GeneID	853706.
KEGG	sce:YKL151C.
NMPDR	fig|4932.3.peg.3750.
Organism-specific databases
CYGD	YKL151c.
SGD	S000001634. YKL151C.
Phylogenomic databases
eggNOG	fuNOG06060.
GeneTree	EFGT00050000004894.
HOGENOM	HBG622920.
OMA	LTPNVNE.
OrthoDB	EOG43R6WS.
Gene expression databases
ArrayExpress	P36059.
Genevestigator	P36059.
GermOnline	YKL151C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR017953. Carbohydrate_kinase_pred_CS. IPR000631. UPF_carb_kinase-rel. [Graphical view]
Pfam	PF01256. Carb_kinase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00196. YjeF_C. 1 hit.
PROSITE	PS01049. YJEF_C_1. 1 hit. PS01050. YJEF_C_2. 1 hit. PS51383. YJEF_C_3. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	974704.

Entry information

Entry name

YKP1_YEAST

Accession

Primary (citable) accession number: P36059
Secondary accession number(s): D6VX46, Q6Q5N3

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 1, 1994
Last sequence update:	June 1, 1994
Last modified:	January 25, 2012
This is version 85 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program