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Protein

37S ribosomal protein S22, mitochondrial

Gene

RSM22

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • methyltransferase activity Source: UniProtKB-KW
  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • mitochondrial translation Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Ribonucleoprotein, Ribosomal protein, Transferase

Enzyme and pathway databases

BioCyciYEAST:G3O-31925-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
37S ribosomal protein S22, mitochondrial (EC:2.1.1.-)
Gene namesi
Name:RSM22
Ordered Locus Names:YKL155C
ORF Names:YKL610
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XI

Organism-specific databases

EuPathDBiFungiDB:YKL155C.
SGDiS000001638. RSM22.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial small ribosomal subunit Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 1515MitochondrionSequence analysisAdd
BLAST
Chaini16 – 62861337S ribosomal protein S22, mitochondrialPRO_0000203144Add
BLAST

Proteomic databases

MaxQBiP36056.

PTM databases

iPTMnetiP36056.

Interactioni

Subunit structurei

Component of the mitochondrial small ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S).2 Publications

Protein-protein interaction databases

BioGridi33982. 41 interactions.
DIPiDIP-756N.
IntActiP36056. 7 interactions.
MINTiMINT-638530.

Structurei

3D structure databases

ProteinModelPortaliP36056.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

HOGENOMiHOG000246590.
InParanoidiP36056.
OMAiQIMIRPE.
OrthoDBiEOG7HQNHQ.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
InterProiIPR015324. Ribosomal_Rsm22_bac-type.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF09243. Rsm22. 2 hits.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 2 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P36056-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMKRCFSILP QNVRFSSKFT SLNLPKLDLA DFIDSNKRGI NVLPSYRDET
60 70 80 90 100
ASTTQATNSK ELRLLSKTLQ GQSYRDQLEL NPDVSKAINN NIMAVHIPNN
110 120 130 140 150
LRRVATNYYK EIQEPNSLHR PCRTKMEVDA HIASIFLQNY GSIFQSLKEL
160 170 180 190 200
QKRVGPDNFK PQRILDVGYG PATGIVALND ILGPNYRPDL KDAVILGNAE
210 220 230 240 250
MQERAKIILS RQLNEVVDTV EENVSTEKEQ ETDRRNKNFQ EDEHIGEVMT
260 270 280 290 300
KKINIMTNLR SSIPASKEYD LIILTHQLLH DGNQFPIQVD ENIEHYLNIL
310 320 330 340 350
APGGHIVIIE RGNPMGFEII ARARQITLRP ENFPDEFGKI PRPWSRGVTV
360 370 380 390 400
RGKKDAELGN ISSNYFLKVI APCPHQRKCP LQVGNPNFYT HKEGKDLKFC
410 420 430 440 450
NFQKSIKRPK FSIELKKGKL LATSWDGSQG NASRLKGTGR RNGRDYEILN
460 470 480 490 500
YSYLIFERSH KDENTLKEIK KLRNENVNGK YDIGSLGDDT QNSWPRIIND
510 520 530 540 550
PVKRKGHVMM DLCAPSGELE KWTVSRSFSK QIYHDARKSK KGDLWASAAK
560 570 580 590 600
TQIKGLGDLN VKKFHKLEKE RIKQLKKEER QKARKAMESY NELEDSLQFD
610 620
DHQFSNFEVM KKLSTFHGND FLQHVNRK
Length:628
Mass (Da):72,190
Last modified:June 1, 1994 - v1
Checksum:i9612A09DA01CD969
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z26877 Genomic DNA. Translation: CAA81498.1.
Z28155 Genomic DNA. Translation: CAA81996.1.
BK006944 Genomic DNA. Translation: DAA09009.1.
PIRiS37795.
RefSeqiNP_012767.1. NM_001179721.1.

Genome annotation databases

EnsemblFungiiYKL155C; YKL155C; YKL155C.
GeneIDi853701.
KEGGisce:YKL155C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z26877 Genomic DNA. Translation: CAA81498.1.
Z28155 Genomic DNA. Translation: CAA81996.1.
BK006944 Genomic DNA. Translation: DAA09009.1.
PIRiS37795.
RefSeqiNP_012767.1. NM_001179721.1.

3D structure databases

ProteinModelPortaliP36056.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33982. 41 interactions.
DIPiDIP-756N.
IntActiP36056. 7 interactions.
MINTiMINT-638530.

PTM databases

iPTMnetiP36056.

Proteomic databases

MaxQBiP36056.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYKL155C; YKL155C; YKL155C.
GeneIDi853701.
KEGGisce:YKL155C.

Organism-specific databases

EuPathDBiFungiDB:YKL155C.
SGDiS000001638. RSM22.

Phylogenomic databases

HOGENOMiHOG000246590.
InParanoidiP36056.
OMAiQIMIRPE.
OrthoDBiEOG7HQNHQ.

Enzyme and pathway databases

BioCyciYEAST:G3O-31925-MONOMER.

Miscellaneous databases

PROiP36056.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
InterProiIPR015324. Ribosomal_Rsm22_bac-type.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF09243. Rsm22. 2 hits.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 2 hits.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "DNA sequencing of a 36.2 kb fragment located between the FAS1 and LAP loci of chromosome XI of Saccharomyces cerevisiae."
    Vandenbol M., Bolle P.-A., Dion C., Portetelle D., Hilger F.
    Yeast 10:S35-S40(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. "Complete DNA sequence of yeast chromosome XI."
    Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C.
    , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
    Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. "Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues."
    Saveanu C., Fromont-Racine M., Harington A., Ricard F., Namane A., Jacquier A.
    J. Biol. Chem. 276:15861-15867(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION, IDENTIFICATION IN THE MITOCHONDRIAL RIBOSOMAL SMALL COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY.
  5. "Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components."
    Gan X., Kitakawa M., Yoshino K., Oshiro N., Yonezawa K., Isono K.
    Eur. J. Biochem. 269:5203-5214(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION IN THE MITOCHONDRIAL RIBOSOMAL SMALL COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY.
  6. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  7. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  8. "Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics."
    Reinders J., Zahedi R.P., Pfanner N., Meisinger C., Sickmann A.
    J. Proteome Res. 5:1543-1554(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiRT22_YEAST
AccessioniPrimary (citable) accession number: P36056
Secondary accession number(s): D6VX43
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: June 8, 2016
This is version 122 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1900 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XI
    Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.