Reviewed,
UniProtKB/Swiss-Prot P36054 (RCN1_YEAST)
Last modified
November 3, 2009.
Version 67.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Calcipressin-like protein Alternative name(s): Regulator of calcineurin 1 Down syndrome candidate region 1-like protein | ||||||||
| Gene names |
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| Organism | Saccharomyces cerevisiae (Baker's yeast) [Complete proteome] | ||||||||
| Taxonomic identifier | 4932 [NCBI] | ||||||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 211 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin. |
| Miscellaneous | Present with 521 molecules/cell in log phase SD medium. Ref.5 |
| Sequence similarities | Belongs to the RCAN family. |
Ontologies
| Keywords | |
|---|---|
| PTM | Phosphoprotein |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | calcium-mediated signaling Ref.4 Inferred from mutant phenotype. Source: SGD |
| Cellular component | cytoplasm Ref.4 Inferred by curator. Source: SGD |
| Molecular function | calcium-dependent protein serine/threonine phosphatase regulator activity Ref.4 Inferred from genetic interaction. Source: SGD protein phosphatase 2B binding Ref.4Inferred from direct assay. Source: SGD |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "A new gene family including DSCR1 (Down syndrome candidate region 1) and ZAKI-4: characterization from yeast to human and identification of DSCR1-like 2, a novel human member (DSCR1L2)." Strippoli P., Lenzi L., Petrini M., Carinci P., Zannotti M. Genomics 64:252-263(2000) [PubMed: 10756093] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: CG1945. |
| [2] | "DNA sequencing of a 36.2 kb fragment located between the FAS1 and LAP loci of chromosome XI of Saccharomyces cerevisiae." Vandenbol M., Bolle P.-A., Dion C., Portetelle D., Hilger F. Yeast 10:S35-S40(1994) [PubMed: 8091859] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c. |
| [3] | "Complete DNA sequence of yeast chromosome XI." Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C. Mewes H.-W.Nature 369:371-378(1994) [PubMed: 8196765] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c. |
| [4] | "A conserved family of calcineurin regulators." Kingsbury T.J., Cunningham K.W. Genes Dev. 14:1595-1604(2000) [PubMed: 10887154] [Abstract] Cited for: CHARACTERIZATION. |
| [5] | "Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]. |
| [6] | "A multidimensional chromatography technology for in-depth phosphoproteome analysis." Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H. Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-117, MASS SPECTROMETRY. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| AF174139 mRNA. Translation: AAF01680.1. Z26877 Genomic DNA. Translation: CAA81495.1. Z28159 Genomic DNA. Translation: CAA82001.1. | |
| PIR | S37792. |
| RefSeq | NP_012763.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| IntAct | P36054. 5 interactions. |
| STRING | P36054. |
Proteomic databases | |
| PRIDE | P36054. |
Genome annotation databases | |
| Ensembl | YKL159C; YKL159C; YKL159C; Saccharomyces cerevisiae. [Genome view] |
| GeneID | 853698. |
| GenomeReviews | Gene locus YKL159C in contig Y13137_GR. |
| KEGG | sce:YKL159C. |
| NMPDR | fig|4932.3.peg.3742. |
Organism-specific databases | |
| CYGD | YKL159c. |
| SGD | S000001642. RCN1. |
Phylogenomic databases | |
| HOGENOM | P36054. |
| OMA | PPPEFDF. |
Gene expression databases | |
| ArrayExpress | P36054. |
| Genevestigator | P36054. |
| GermOnline | YKL159C. Saccharomyces cerevisiae. |
Family and domain databases | |
| InterPro | IPR006931. Calcipressin. IPR016523. UCP007798. [Graphical view] |
| Pfam | PF04847. Calcipressin. 1 hit. [Graphical view] |
| PIRSF | PIRSF007798. UCP007798. 1 hit. |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 974684. |
Entry information
| Entry name | RCN1_YEAST | ||||||||
| Accession | Primary (citable) accession number: P36054 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |
| Yeast chromosome XI Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names |

Clusters with


