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P36038

- CBT1_YEAST

UniProt

P36038 - CBT1_YEAST

Protein

Cytochrome b termination protein 1

Gene

CBT1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 96 (01 Oct 2014)
      Sequence version 1 (01 Jun 1994)
      Previous versions | rss
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    Functioni

    Involved in 5'-end processing of mitochondrial COB, 15S rRNA, and RPM1 transcript. May also have a role in 3'-end processing of the COB pre-mRNA.4 Publications

    GO - Biological processi

    1. cytochrome complex assembly Source: SGD
    2. mRNA processing Source: SGD
    3. mRNA stabilization Source: SGD
    4. rRNA processing Source: UniProtKB-KW

    Keywords - Biological processi

    mRNA processing, Ribosome biogenesis, rRNA processing

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31967-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome b termination protein 1
    Gene namesi
    Name:CBT1
    Synonyms:SOC1
    Ordered Locus Names:YKL208W
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome XI

    Organism-specific databases

    CYGDiYKL208w.
    SGDiS000001691. CBT1.

    Subcellular locationi

    Mitochondrion 1 Publication

    GO - Cellular componenti

    1. mitochondrion Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Mitochondrion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 271271Cytochrome b termination protein 1PRO_0000203131Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriP36038.

    Interactioni

    Protein-protein interaction databases

    BioGridi33958. 118 interactions.
    DIPiDIP-3855N.
    MINTiMINT-490655.
    STRINGi4932.YKL208W.

    Structurei

    3D structure databases

    ProteinModelPortaliP36038.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG131984.
    OMAiSESEHEY.
    OrthoDBiEOG7RV9SF.

    Sequencei

    Sequence statusi: Complete.

    P36038-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVSYGSHSSE VSKVLKTPKF VLRYGNVSSK QRFALKRKIN YKLRESKYQE    50
    YLNEYNTFVL YDWENSGAGS LVDSSYNLPS LWKEFITEGI SKGAINDKLP 100
    TVFMKRKLTN SALGHCLGLD FLTDPSESEH EYRCMFQTVQ DIPSLSQLIL 150
    FNSMPNVPVR LKLHTIGINI NFGCKRSLIS NGGDQDTEMS EAVSYIQPLL 200
    EESSRMYRNL NYWKLLKIAR NNKKDEPLDQ STRIKSQVKL LLSQLATNRI 250
    TSPSVTDHGG HNWLIFTRRR L 271
    Length:271
    Mass (Da):31,157
    Last modified:June 1, 1994 - v1
    Checksum:i6022348CA619123C
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti270 – 2701R → Q in AAS56721. (PubMed:17322287)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z28208 Genomic DNA. Translation: CAA82053.1.
    AY558395 Genomic DNA. Translation: AAS56721.1.
    BK006944 Genomic DNA. Translation: DAA08961.1.
    PIRiS38046.
    RefSeqiNP_012714.1. NM_001179773.1.

    Genome annotation databases

    EnsemblFungiiYKL208W; YKL208W; YKL208W.
    GeneIDi853673.
    KEGGisce:YKL208W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z28208 Genomic DNA. Translation: CAA82053.1 .
    AY558395 Genomic DNA. Translation: AAS56721.1 .
    BK006944 Genomic DNA. Translation: DAA08961.1 .
    PIRi S38046.
    RefSeqi NP_012714.1. NM_001179773.1.

    3D structure databases

    ProteinModelPortali P36038.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 33958. 118 interactions.
    DIPi DIP-3855N.
    MINTi MINT-490655.
    STRINGi 4932.YKL208W.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YKL208W ; YKL208W ; YKL208W .
    GeneIDi 853673.
    KEGGi sce:YKL208W.

    Organism-specific databases

    CYGDi YKL208w.
    SGDi S000001691. CBT1.

    Phylogenomic databases

    eggNOGi NOG131984.
    OMAi SESEHEY.
    OrthoDBi EOG7RV9SF.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31967-MONOMER.

    Miscellaneous databases

    NextBioi 974622.

    Gene expression databases

    Genevestigatori P36038.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Complete DNA sequence of yeast chromosome XI."
      Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C.
      , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
      Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. "Suppressor analyses of temperature-sensitive cbp1 strains of Saccharomyces cerevisiae: the product of the nuclear gene SOC1 affects mitochondrial cytochrome b mRNA post-transcriptionally."
      Staples R.R., Dieckmann C.L.
      Genetics 138:565-575(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    5. "A novel nuclear gene, CBT1, essential for mitochondrial cytochrome b formation: terminal processing of mRNA and intron dependence."
      Rieger K.-J., Aljinovic G., Lazowska J., Pohl T.M., Slonimski P.P., Aljinovic G.
      Curr. Genet. 32:163-174(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    6. "Suppressor analysis of mutations in the 5'-untranslated region of COB mRNA identifies components of general pathways for mitochondrial mRNA processing and decay in Saccharomyces cerevisiae."
      Chen W., Islas-Osuna M.A., Dieckmann C.L.
      Genetics 151:1315-1325(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    7. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    8. "CBT1 interacts genetically with CBP1 and the mitochondrially encoded cytochrome b gene and is required to stabilize the mature cytochrome b mRNA of Saccharomyces cerevisiae."
      Ellis T.P., Schonauer M.S., Dieckmann C.L.
      Genetics 171:949-957(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.

    Entry informationi

    Entry nameiCBT1_YEAST
    AccessioniPrimary (citable) accession number: P36038
    Secondary accession number(s): D6VWZ5, Q6Q574
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 1, 1994
    Last sequence update: June 1, 1994
    Last modified: October 1, 2014
    This is version 96 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    2. Yeast chromosome XI
      Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

    External Data

    Dasty 3