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P36038

- CBT1_YEAST

UniProt

P36038 - CBT1_YEAST

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Protein

Cytochrome b termination protein 1

Gene

CBT1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Involved in 5'-end processing of mitochondrial COB, 15S rRNA, and RPM1 transcript. May also have a role in 3'-end processing of the COB pre-mRNA.4 Publications

GO - Biological processi

  1. cytochrome complex assembly Source: SGD
  2. mRNA processing Source: SGD
  3. mRNA stabilization Source: SGD
  4. rRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

mRNA processing, Ribosome biogenesis, rRNA processing

Enzyme and pathway databases

BioCyciYEAST:G3O-31967-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome b termination protein 1
Gene namesi
Name:CBT1
Synonyms:SOC1
Ordered Locus Names:YKL208W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome XI

Organism-specific databases

CYGDiYKL208w.
SGDiS000001691. CBT1.

Subcellular locationi

Mitochondrion 1 Publication

GO - Cellular componenti

  1. mitochondrion Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 271271Cytochrome b termination protein 1PRO_0000203131Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP36038.

Interactioni

Protein-protein interaction databases

BioGridi33958. 118 interactions.
DIPiDIP-3855N.
MINTiMINT-490655.
STRINGi4932.YKL208W.

Structurei

3D structure databases

ProteinModelPortaliP36038.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG131984.
InParanoidiP36038.
OMAiSESEHEY.
OrthoDBiEOG7RV9SF.

Sequencei

Sequence statusi: Complete.

P36038-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVSYGSHSSE VSKVLKTPKF VLRYGNVSSK QRFALKRKIN YKLRESKYQE
60 70 80 90 100
YLNEYNTFVL YDWENSGAGS LVDSSYNLPS LWKEFITEGI SKGAINDKLP
110 120 130 140 150
TVFMKRKLTN SALGHCLGLD FLTDPSESEH EYRCMFQTVQ DIPSLSQLIL
160 170 180 190 200
FNSMPNVPVR LKLHTIGINI NFGCKRSLIS NGGDQDTEMS EAVSYIQPLL
210 220 230 240 250
EESSRMYRNL NYWKLLKIAR NNKKDEPLDQ STRIKSQVKL LLSQLATNRI
260 270
TSPSVTDHGG HNWLIFTRRR L
Length:271
Mass (Da):31,157
Last modified:June 1, 1994 - v1
Checksum:i6022348CA619123C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti270 – 2701R → Q in AAS56721. (PubMed:17322287)Curated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z28208 Genomic DNA. Translation: CAA82053.1.
AY558395 Genomic DNA. Translation: AAS56721.1.
BK006944 Genomic DNA. Translation: DAA08961.1.
PIRiS38046.
RefSeqiNP_012714.1. NM_001179773.1.

Genome annotation databases

EnsemblFungiiYKL208W; YKL208W; YKL208W.
GeneIDi853673.
KEGGisce:YKL208W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z28208 Genomic DNA. Translation: CAA82053.1 .
AY558395 Genomic DNA. Translation: AAS56721.1 .
BK006944 Genomic DNA. Translation: DAA08961.1 .
PIRi S38046.
RefSeqi NP_012714.1. NM_001179773.1.

3D structure databases

ProteinModelPortali P36038.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 33958. 118 interactions.
DIPi DIP-3855N.
MINTi MINT-490655.
STRINGi 4932.YKL208W.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YKL208W ; YKL208W ; YKL208W .
GeneIDi 853673.
KEGGi sce:YKL208W.

Organism-specific databases

CYGDi YKL208w.
SGDi S000001691. CBT1.

Phylogenomic databases

eggNOGi NOG131984.
InParanoidi P36038.
OMAi SESEHEY.
OrthoDBi EOG7RV9SF.

Enzyme and pathway databases

BioCyci YEAST:G3O-31967-MONOMER.

Miscellaneous databases

NextBioi 974622.

Gene expression databases

Genevestigatori P36038.

Family and domain databases

ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete DNA sequence of yeast chromosome XI."
    Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C.
    , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
    Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. "Suppressor analyses of temperature-sensitive cbp1 strains of Saccharomyces cerevisiae: the product of the nuclear gene SOC1 affects mitochondrial cytochrome b mRNA post-transcriptionally."
    Staples R.R., Dieckmann C.L.
    Genetics 138:565-575(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  5. "A novel nuclear gene, CBT1, essential for mitochondrial cytochrome b formation: terminal processing of mRNA and intron dependence."
    Rieger K.-J., Aljinovic G., Lazowska J., Pohl T.M., Slonimski P.P., Aljinovic G.
    Curr. Genet. 32:163-174(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  6. "Suppressor analysis of mutations in the 5'-untranslated region of COB mRNA identifies components of general pathways for mitochondrial mRNA processing and decay in Saccharomyces cerevisiae."
    Chen W., Islas-Osuna M.A., Dieckmann C.L.
    Genetics 151:1315-1325(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  7. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  8. "CBT1 interacts genetically with CBP1 and the mitochondrially encoded cytochrome b gene and is required to stabilize the mature cytochrome b mRNA of Saccharomyces cerevisiae."
    Ellis T.P., Schonauer M.S., Dieckmann C.L.
    Genetics 171:949-957(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.

Entry informationi

Entry nameiCBT1_YEAST
AccessioniPrimary (citable) accession number: P36038
Secondary accession number(s): D6VWZ5, Q6Q574
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: October 29, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XI
    Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

External Data

Dasty 3