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P36038 (CBT1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome b termination protein 1
Gene names
Name:CBT1
Synonyms:SOC1
Ordered Locus Names:YKL208W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length271 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Involved in 5'-end processing of mitochondrial COB, 15S rRNA, and RPM1 transcript. May also have a role in 3'-end processing of the COB pre-mRNA. Ref.4 Ref.5 Ref.6 Ref.8

Subcellular location

Mitochondrion Ref.7.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 271271Cytochrome b termination protein 1
PRO_0000203131

Experimental info

Sequence conflict2701R → Q in AAS56721. Ref.3

Sequences

Sequence LengthMass (Da)Tools
P36038 [UniParc].

Last modified June 1, 1994. Version 1.
Checksum: 6022348CA619123C

FASTA27131,157
        10         20         30         40         50         60 
MVSYGSHSSE VSKVLKTPKF VLRYGNVSSK QRFALKRKIN YKLRESKYQE YLNEYNTFVL 

        70         80         90        100        110        120 
YDWENSGAGS LVDSSYNLPS LWKEFITEGI SKGAINDKLP TVFMKRKLTN SALGHCLGLD 

       130        140        150        160        170        180 
FLTDPSESEH EYRCMFQTVQ DIPSLSQLIL FNSMPNVPVR LKLHTIGINI NFGCKRSLIS 

       190        200        210        220        230        240 
NGGDQDTEMS EAVSYIQPLL EESSRMYRNL NYWKLLKIAR NNKKDEPLDQ STRIKSQVKL 

       250        260        270 
LLSQLATNRI TSPSVTDHGG HNWLIFTRRR L 

« Hide

References

« Hide 'large scale' references
[1]"Complete DNA sequence of yeast chromosome XI."
Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C. expand/collapse author list , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]"Suppressor analyses of temperature-sensitive cbp1 strains of Saccharomyces cerevisiae: the product of the nuclear gene SOC1 affects mitochondrial cytochrome b mRNA post-transcriptionally."
Staples R.R., Dieckmann C.L.
Genetics 138:565-575(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
[5]"A novel nuclear gene, CBT1, essential for mitochondrial cytochrome b formation: terminal processing of mRNA and intron dependence."
Rieger K.-J., Aljinovic G., Lazowska J., Pohl T.M., Slonimski P.P., Aljinovic G.
Curr. Genet. 32:163-174(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
[6]"Suppressor analysis of mutations in the 5'-untranslated region of COB mRNA identifies components of general pathways for mitochondrial mRNA processing and decay in Saccharomyces cerevisiae."
Chen W., Islas-Osuna M.A., Dieckmann C.L.
Genetics 151:1315-1325(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
[7]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[8]"CBT1 interacts genetically with CBP1 and the mitochondrially encoded cytochrome b gene and is required to stabilize the mature cytochrome b mRNA of Saccharomyces cerevisiae."
Ellis T.P., Schonauer M.S., Dieckmann C.L.
Genetics 171:949-957(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z28208 Genomic DNA. Translation: CAA82053.1.
AY558395 Genomic DNA. Translation: AAS56721.1.
BK006944 Genomic DNA. Translation: DAA08961.1.
PIRS38046.
RefSeqNP_012714.1. NM_001179773.1.

3D structure databases

ProteinModelPortalP36038.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33958. 118 interactions.
DIPDIP-3855N.
MINTMINT-490655.
STRING4932.YKL208W.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYKL208W; YKL208W; YKL208W.
GeneID853673.
KEGGsce:YKL208W.

Organism-specific databases

CYGDYKL208w.
SGDS000001691. CBT1.

Phylogenomic databases

eggNOGNOG131984.
OMASESEHEY.
OrthoDBEOG7RV9SF.

Enzyme and pathway databases

BioCycYEAST:G3O-31967-MONOMER.

Gene expression databases

GenevestigatorP36038.

Family and domain databases

ProtoNetSearch...

Other

NextBio974622.

Entry information

Entry nameCBT1_YEAST
AccessionPrimary (citable) accession number: P36038
Secondary accession number(s): D6VWZ5, Q6Q574
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: February 19, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XI

Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD