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P36026 (UBP11_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ubiquitin carboxyl-terminal hydrolase 11

EC=3.4.19.12
Alternative name(s):
Deubiquitinating enzyme 11
Ubiquitin thioesterase 11
Ubiquitin-specific-processing protease 11
Gene names
Name:UBP11
Ordered Locus Names:YKR098C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length717 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).

Sequence similarities

Belongs to the peptidase C19 family.

Contains 1 USP domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 717717Ubiquitin carboxyl-terminal hydrolase 11
PRO_0000080596

Regions

Domain298 – 707410USP
Compositional bias557 – 5648Poly-His

Sites

Active site3071Nucleophile By similarity
Active site6491Proton acceptor By similarity

Sequences

Sequence LengthMass (Da)Tools
P36026 [UniParc].

Last modified June 1, 1994. Version 1.
Checksum: 9BAA1EEEB5DD9A65

FASTA71782,703
        10         20         30         40         50         60 
MLLNPDQILN LVRKVYEVDI KQFYSQLRLK NLRGLLDHAA HLFNVYLRDL EINQEMEALT 

        70         80         90        100        110        120 
AFIIGCYYLY LIIPQSLQFQ TRNNLYSSYA KLKNDYQDEH VMGYVLKVVR DESTVIVDRY 

       130        140        150        160        170        180 
LAESNGICRT IKRKRAYSLP LRPLPVHMAS LSIHNKFDGS LHEIPNELTK PTNDNSKEDI 

       190        200        210        220        230        240 
VRESNQIASS NKLEAGSEVA YYTSKEALSK PSYLKLSTGK DALFKTLSSP ATAPPVHSLE 

       250        260        270        280        290        300 
VSSQIRDSSQ DSSSSLSKVE KPKEEEGKIE AIESSAPKAY NLPVIEDSND LLSELSITGL 

       310        320        330        340        350        360 
QNPCNTCYIN SIIQCLFGTT LFRDLFLTKK YRLFLNTNKY PKEVQLSRSI YVLFKKMYLN 

       370        380        390        400        410        420 
GGRAIIPNRF LKMCKKLRPD LNIPDDQQDT QEFLLIVLAR IHEELSNENV VKYYPDLVSY 

       430        440        450        460        470        480 
DANALQVNPS KYEKWYERNV ITDGLSPIDH IYRGQLENIL KCQRCGNSSY SYSTFYVLSL 

       490        500        510        520        530        540 
AIPKLSLYSF TSKSRKIKLE DCINLFTGDE ELSGDNAWDC PNCRITDSKS KKEEITSQKK 

       550        560        570        580        590        600 
KSTIFGFHSR SRSKSPHHHH HHHHSSDDST KNAKKRNSKK LTTIKSLDFI VLPPILVIHL 

       610        620        630        640        650        660 
SRFYYDLTKK NSTVITYPLI LNIILKNGKV IRYKLYGTVN HSGNLINGHY TSVVNKEKSH 

       670        680        690        700        710 
EIGLNRQVWV TFDDDYIQQH RKDRNNFEAG KTEMSSDEVY VLFYERMDEE NYEEEFC 

« Hide

References

« Hide 'large scale' references
[1]"Complete DNA sequence of yeast chromosome XI."
Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C. expand/collapse author list , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z28323 Genomic DNA. Translation: CAA82178.1.
BK006944 Genomic DNA. Translation: DAA09249.1.
PIRS38177.
RefSeqNP_013024.1. NM_001179888.1.

3D structure databases

ProteinModelPortalP36026.
SMRP36026. Positions 298-707.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid34229. 24 interactions.
IntActP36026. 1 interaction.
MINTMINT-2785419.
STRING4932.YKR098C.

Protein family/group databases

MEROPSC19.102.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYKR098C; YKR098C; YKR098C.
GeneID853973.
KEGGsce:YKR098C.

Organism-specific databases

CYGDYKR098c.
SGDS000001806. UBP11.

Phylogenomic databases

eggNOGCOG5533.
GeneTreeENSGT00670000099202.
HOGENOMHOG000142359.
KOK11871.
OrthoDBEOG7R2BSX.

Enzyme and pathway databases

BioCycYEAST:G3O-32060-MONOMER.

Gene expression databases

GenevestigatorP36026.

Family and domain databases

InterProIPR018200. Pept_C19ubi-hydrolase_C_CS.
IPR001394. Peptidase_C19_UCH.
IPR028889. UCH/PAN2.
[Graphical view]
PfamPF00443. UCH. 1 hit.
[Graphical view]
PROSITEPS00972. USP_1. 1 hit.
PS00973. USP_2. 1 hit.
PS50235. USP_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio975422.

Entry information

Entry nameUBP11_YEAST
AccessionPrimary (citable) accession number: P36026
Secondary accession number(s): D6VXF9
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: April 16, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XI

Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries