P36011 (STUA_EMENI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cell pattern formation-associated protein stuA

Gene names

Name:	stuA
ORF Names:	AN5836

Organism

Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) [Reference proteome]

Taxonomic identifier

227321 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › Emericella › Emericella nidulans › mitosporic Emericella nidulans

Protein attributes

Sequence length	622 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Required for the orderly differentiation and spatial organization of cell types of the conidiophore. Affects the spatial localization of abaA and brlA. Expression of stuA is dependent on a functional brlA protein.
Subcellular location	Nucleus Potential.
Developmental stage	Expression is increased 50-fold during the establishment of developmental competence.
Sequence similarities	Belongs to the EFG1/PHD1/stuA family. Contains 1 HTH APSES-type DNA-binding domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Ligand	DNA-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 622	622	Cell pattern formation-associated protein stuA		PRO_0000072296
Regions
	Domain	129 – 235	107	HTH APSES-type
	DNA binding	163 – 184	22	H-T-H motif By similarity
	Compositional bias	39 – 129	91	Gln/Pro/Ser-rich
	Compositional bias	253 – 415	163	Gln/Pro/Ser-rich

Sequences

	Sequence		Length	Mass (Da)
	P36011 [UniParc]. Last modified March 15, 2004. Version 2. Checksum: 05D8AE2FAF497083	FASTA	622	66,956
	10 20 30 40 50 60 MASMNQPQPY MDVHSHLSSG QTYASHPATA GALTHYQYPQ QPPVLQPTST YGPASSYSQY 70 80 90 100 110 120 PYPNSVASSQ SVPPPTTSIS SQVPAQLLPL PVTNHPVPTH GYGNNSGTPM QGYVYDPTGQ 130 140 150 160 170 180 MAPPGAKPRV TATLWEDEGS LCYQVEAKGV CVARREDNGM INGTKLLNVA GMTRGRRDGI 190 200 210 220 230 240 LKSEKVRNVV KIGPMHLKGV WIPFDRALEF ANKEKITDLL YPLFVQHISN LLYHPANQNQ 250 260 270 280 290 300 RNMTVPDSRR LEGPQPVVRT PQAQQPPSLH HHSLQTPVPS HMSQPGGRPS LDRAHTFPTP 310 320 330 340 350 360 PASASSLIGI TSQNNSYDWN PGMNSSVPNT QPLSIDTSLS NARSMPTTPA TTPPGNNLQG 370 380 390 400 410 420 MQSYQPQSGY DSKPYYSAAP STHPQYAPQQ PLPQQSMAQY GHSMPTSSYR DMAPPSSQRG 430 440 450 460 470 480 SVTEIESDVK TERYGQGTVA KTEPEQEQEY AQPDSGYNTG RGSYYTTNPS VGGLAHDHSQ 490 500 510 520 530 540 LTPDMTGSPQ QNGSGRMTPR TSNTAPQWAP GYTTPPRPAA ASSLYNIVSD TRGTSGANGS 550 560 570 580 590 600 TSDNYSVASN SGYSTGMNGS MGSNKRMRDD DDDRIVPPDS RGEFDTKRRK TLTETPVGGP 610 620 VGGVPLGLQP MKAGGSLISA RR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"StuA is required for cell pattern formation in Aspergillus." Miller K.Y., Wu J., Miller B.L. Genes Dev. 6:1770-1782(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	Miller B.L. Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases Cited for: SEQUENCE REVISION.
[3]	"Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae." Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S., Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V., Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S., Braus G.H. , Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H., Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K., Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R., Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C., Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L., Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W. Nature 438:1105-1115(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139.
[4]	"The 2008 update of the Aspergillus nidulans genome annotation: a community effort." Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J., Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H., Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M., Estrada C.G. , Geysens S., Goldman G., de Groot P.W., Hansen K., Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G., Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L., Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M., van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P., Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J., Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A., Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X., Robson G., Seiboth B., van Solingen P., Specht T., Sun J., Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H., van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y., Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J., Oliver S.G., Turner G. Fungal Genet. Biol. 46:S2-13(2009) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M83569 Genomic DNA. Translation: AAA33325.2. AACD01000100 Genomic DNA. Translation: EAA58345.1. BN001301 Genomic DNA. Translation: CBF70741.1.
PIR	A44068.
RefSeq	XP_663440.1. XM_658348.1.
3D structure databases
ProteinModelPortal	P36011.
ModBase	Search...
Protein-protein interaction databases
STRING	162425.CADANIAP00007206.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	CADANIAT00007206; CADANIAP00007206; CADANIAG00007206.
GeneID	2870743.
KEGG	ani:AN5836.2.
Phylogenomic databases
eggNOG	NOG41372.
HOGENOM	HOG000213682.
KO	K12763.
OMA	SNARSMP.
OrthoDB	EOG4D565W.
Family and domain databases
Gene3D	3.10.260.10. 1 hit.
InterPro	IPR018004. KilA_N/APSES_HTH. IPR003163. Tscrpt_reg_HTH_APSES-type. [Graphical view]
Pfam	PF04383. KilA-N. 1 hit. [Graphical view]
SUPFAM	SSF54616. Mlu1-box-bd_prot_DNA-bd. 1 hit.
PROSITE	PS51299. HTH_APSES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

STUA_EMENI

Accession

Primary (citable) accession number: P36011
Secondary accession number(s): C8V024, Q5B0U4

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 1, 1994
Last sequence update:	March 15, 2004
Last modified:	April 3, 2013
This is version 72 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program