Reviewed, UniProtKB/Swiss-Prot P36005 (KKQ1_YEAST)

Names and origin

Protein names

Recommended name:
    Probable serine/threonine-protein kinase YKL161C
    EC=2.7.11.1

Gene names

Ordered Locus Names:	YKL161C
ORF Names:	YKL615

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	433 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein.
Sequence similarities	Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Contains 1 protein kinase domain.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein amino acid phosphorylation Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine kinase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 433	433	Probable serine/threonine-protein kinase YKL161C		PRO_0000086150
Regions
	Domain	23 – 318	296	Protein kinase
	Nucleotide binding	29 – 37	9	ATP By similarity
Sites
	Active site	153	1	Proton acceptor By similarity
	Binding site	55	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	P36005-1 [UniParc]. Last modified June 1, 1994. Version 1. Checksum: BC27B76B7DB95822	FASTA	433	49,633
	10 20 30 40 50 60 MATDTERCIF RAFGQDFILN KHFHLTGKIG RGSHSLICSS TYTESNEETH VAIRKIPNAF 70 80 90 100 110 120 GNKLSCKRTL RELKLLRHLR GHPNIVWLFD TDIVFYPNGA LNGVYLYEEL MECDLSQIIR 130 140 150 160 170 180 SEQRLEDAHF QSFIYQILCA LKYIHSANVL HCDLKPKNLL VNSDCQLKIC NFGLSCSYSE 190 200 210 220 230 240 NHKVNDGFIK GYITSIWYKA PEILLNYQEC TKAVDIWSTG CILAELLGRK PMFEGKDYVD 250 260 270 280 290 300 HLNHILQILG TPPEETLQEI ASQKVYNYIF QFGNIPGRSF ESILPGANPE ALELLKKMLE 310 320 330 340 350 360 FDPKKRITVE DALEHPYLSM WHDIDEEFSC QKTFRFEFEH IESMAELGNE VIKEVFDFRK 370 380 390 400 410 420 VVRKHPISGD SPSSSLSLED AIPQEVVQVH PSRKVLPSYS PEFSYVSQLP SLTTTQPYQN 430 LMGISSNSFQ GVN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"DNA sequencing of a 36.2 kb fragment located between the FAS1 and LAP loci of chromosome XI of Saccharomyces cerevisiae." Vandenbol M., Bolle P.-A., Dion C., Portetelle D., Hilger F. Yeast 10:S35-S40(1994) [PubMed: 8091859] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[2]	"Complete DNA sequence of yeast chromosome XI." Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C. , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W. Nature 369:371-378(1994) [PubMed: 8196765] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Z26877 Genomic DNA. Translation: CAA81493.1. Z28161 Genomic DNA. Translation: CAA82003.1.
PIR	S37790.
RefSeq	NP_012761.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-6316N.
IntAct	P36005. 12 interactions.
STRING	P36005.
Proteomic databases
PeptideAtlas	P36005.
PRIDE	P36005.
Genome annotation databases
Ensembl	YKL161C; YKL161C; YKL161C; Saccharomyces cerevisiae. [Genome view]
GeneID	853696.
KEGG	sce:YKL161C.
NMPDR	fig|4932.3.peg.3740.
Organism-specific databases
CYGD	YKL161c.
SGD	S000001644. YKL161C.
Phylogenomic databases
HOGENOM	HBG755340.
OMA	ESNEETH.
OrthoDB	EOG9X3JJS.
Enzyme and pathway databases
BRENDA	2.7.11.1. 250.
Gene expression databases
ArrayExpress	P36005.
Genevestigator	P36005.
GermOnline	YKL161C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR017442. Se/Thr_prot_kinase-like_dom. IPR008271. Ser/Thr_prot_kinase_AS. IPR002290. Ser/Thr_prot_kinase_dom. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	974678.

Entry information

Entry name

KKQ1_YEAST

Accession

Primary (citable) accession number: P36005

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 1, 1994
Last sequence update:	June 1, 1994
Last modified:	December 15, 2009
This is version 84 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)