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P35980 (RL18_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 108. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
60S ribosomal protein L18
Gene names
Name:Rpl18
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length188 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Cytoplasm.

Sequence similarities

Belongs to the ribosomal protein L18e family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionRibonucleoprotein
Ribosomal protein
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytosolic large ribosomal subunit

Inferred from electronic annotation. Source: Ensembl

   Molecular_functionstructural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 18818760S ribosomal protein L18
PRO_0000132770

Amino acid modifications

Modified residue1301Phosphoserine By similarity
Modified residue1581Phosphothreonine By similarity

Experimental info

Sequence conflict591P → S in AAA40067. Ref.1
Sequence conflict1091A → V in AAA40067. Ref.1
Sequence conflict1151K → R in BAB24923. Ref.2
Sequence conflict1161A → G in AAA40067. Ref.1
Sequence conflict147 – 1504EVYR → DVFP in AAA40067. Ref.1
Sequence conflict1551A → V in AAA40067. Ref.1
Sequence conflict160 – 1623HSH → YSQ in AAA40067. Ref.1
Sequence conflict173 – 1742KF → RL in AAA40067. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P35980 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 9489EFE201ABF7A1

FASTA18821,645
        10         20         30         40         50         60 
MGVDIRHNKD RKVRRKEPKS QDIYLRLLVK LYRFLARRTN STFNQVVLKR LFMSRTNRPP 

        70         80         90        100        110        120 
LSLSRMIRKM KLPGRENKTA VVVGTVTDDV RILEVPKLKV CALRVSSRAR SRILKAGGKI 

       130        140        150        160        170        180 
LTFDQLALES PKGRGTVLLS GPRKGREVYR HFGKAPGTPH SHTKPYVRSK GRKFERARGR 


RASRGYKN 

« Hide

References

« Hide 'large scale' references
[1]"Sequence analysis of mouse cDNAs encoding ribosomal proteins L12 and L18."
Hou E.W., Li S.S.L.
Gene 130:287-290(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: C57BL/6 X CBA.
Tissue: Lung.
[2]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Embryo, Testis and Tongue.
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: FVB/N-3.
Tissue: Mammary gland.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L04128 mRNA. Translation: AAA40067.1.
AK007263 mRNA. Translation: BAB24923.1.
AK009044 mRNA. Translation: BAB26043.1.
AK010510 mRNA. Translation: BAB26993.1.
AK012580 mRNA. Translation: BAB28332.1.
BC082290 mRNA. Translation: AAH82290.1.
CCDSCCDS39958.1.
PIRJN0779.
RefSeqNP_033103.2. NM_009077.2.
XP_006540783.1. XM_006540720.1.
UniGeneMm.3459.
Mm.422997.

3D structure databases

ProteinModelPortalP35980.
SMRP35980. Positions 1-188.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid202968. 10 interactions.
IntActP35980. 4 interactions.
MINTMINT-1857698.

PTM databases

PhosphoSiteP35980.

Proteomic databases

MaxQBP35980.
PaxDbP35980.
PRIDEP35980.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000072503; ENSMUSP00000072320; ENSMUSG00000059070.
ENSMUST00000075178; ENSMUSP00000103365; ENSMUSG00000059070.
GeneID19899.
KEGGmmu:19899.
UCSCuc009gww.1. mouse.

Organism-specific databases

CTD6141.
MGIMGI:98003. Rpl18.

Phylogenomic databases

eggNOGCOG1727.
HOGENOMHOG000213425.
HOVERGENHBG000875.
InParanoidP35980.
KOK02883.
OMAKVRRTEP.
OrthoDBEOG7PS1GP.
PhylomeDBP35980.
TreeFamTF300202.

Gene expression databases

BgeeP35980.
CleanExMM_RPL18.
GenevestigatorP35980.

Family and domain databases

InterProIPR000039. Ribosomal_L18e.
IPR021131. Ribosomal_L18e/L15P.
IPR021132. Ribosomal_L18e_CS.
[Graphical view]
PANTHERPTHR10934. PTHR10934. 1 hit.
PfamPF00828. Ribosomal_L18e. 1 hit.
[Graphical view]
SUPFAMSSF52080. SSF52080. 1 hit.
PROSITEPS01106. RIBOSOMAL_L18E. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio297433.
PROP35980.
SOURCESearch...

Entry information

Entry nameRL18_MOUSE
AccessionPrimary (citable) accession number: P35980
Secondary accession number(s): Q9CQF1, Q9D987
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: January 23, 2007
Last modified: July 9, 2014
This is version 108 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot