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Protein

60 kDa chaperonin 2

Gene

groL2

Organism
Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperonin 2UniRule annotation
Alternative name(s):
GroEL protein 2UniRule annotation
Protein Cpn60 2UniRule annotation
Gene namesi
Name:groL2UniRule annotation
Synonyms:groEL2UniRule annotation
Ordered Locus Names:blr6979
OrganismiBradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Taxonomic identifieri224911 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
Proteomesi
  • UP000002526 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000632952 – 55060 kDa chaperonin 2Add BLAST549

Proteomic databases

PRIDEiP35861.

Expressioni

Inductioni

Not induced by heat shock.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

GO - Molecular functioni

Protein-protein interaction databases

STRINGi224911.blr6979.

Structurei

3D structure databases

ProteinModelPortaliP35861.
SMRiP35861.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
InParanoidiP35861.
KOiK04077.
OMAiCELNDPL.
OrthoDBiPOG091H00E7.
PhylomeDBiP35861.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P35861-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAKEVKFGV DARDRMLRGV DILHNAVKVT LGPKGRNVVL DKSFGAPRIT
60 70 80 90 100
KDGVTVAKEI ELEDKFENMG AQMVREVASK SADAAGDGTT TATVLAAAIV
110 120 130 140 150
REGAKSVAAG MNPMDLKRGI DMAVEAVVAD LVKNSKKVTS NEEIAQVGTI
160 170 180 190 200
SANGDAEIGK FISDAMKKVG NEGVITVEEA KSLETELEVV EGMQFDRGYI
210 220 230 240 250
SPYFVTNADK MRVEMDDAYV LINEKKLSQL NELLPLLEAV VQSGKPLVII
260 270 280 290 300
AEDVEGEALA TLVVNRLRGG LKVAAVKAPG FGDRRKAMLQ DIAILTGGQA
310 320 330 340 350
ISEDLGIKLE NVTLNMLGRA KKVMIDKENT TIVSGAGKKA DIEARVAQIK
360 370 380 390 400
AQIEETTSDY DREKLQERLA KLAGGVAVIR VGGATEVEVK ERKDRVDDAM
410 420 430 440 450
HATRAAVEEG ILPGGGVALL RASEHLKGIR TKNDDQKTGV EIVRKALSYP
460 470 480 490 500
ARQIAINAGE DGSVIVGKIL EKDQYSYGYD SQTGEYGNLV SKGIIDPTKV
510 520 530 540 550
VRVAIQNAAS VAALLITTEA MVAEVPKKNT GAGGMPPGGG GMGGMGGMDF
Length:550
Mass (Da):58,273
Last modified:January 23, 2007 - v2
Checksum:i4C1DAA55FA499818
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z22604 Genomic DNA. Translation: CAA80318.1.
BA000040 Genomic DNA. Translation: BAC52244.1.
PIRiS35309.
RefSeqiNP_773619.1. NC_004463.1.
WP_011089717.1. NZ_CP011360.1.

Genome annotation databases

EnsemblBacteriaiBAC52244; BAC52244; BAC52244.
GeneIDi1048307.
KEGGibja:blr6979.
PATRICifig|224911.44.peg.7013.

Similar proteinsi

Entry informationi

Entry nameiCH602_BRADU
AccessioniPrimary (citable) accession number: P35861
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: January 23, 2007
Last modified: September 27, 2017
This is version 107 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families