P35850 (XYLB_LACBR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Xylulose kinase
Short name=Xylulokinase
EC=2.7.1.17

Gene names

Name:

xylB

Organism

Lactobacillus brevis

Taxonomic identifier

1580 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	502 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + D-xylulose = ADP + D-xylulose 5-phosphate.
Sequence similarities	Belongs to the FGGY kinase family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Xylose metabolism
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Gene Ontology (GO)
Biological_process	D-xylose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW xylulose metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW xylulokinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 502	502	Xylulose kinase		PRO_0000059552

Sequences

	Sequence		Length	Mass (Da)
	P35850 [UniParc]. Last modified August 14, 2001. Version 2. Checksum: 33B6265CE62CC35E	FASTA	502	55,168
	10 20 30 40 50 60 MGKYVLGVDL GTSAVKVSAL DHSGQIVAQE SFDYDLIQKQ PGYNEQNPED WVSGTTVAIV 70 80 90 100 110 120 RLILNDHLDA SNIEGLSYSG QMHGLVLLDE NKKVLRPAIL WNDTRSTPQR EEIEAKLGDE 130 140 150 160 170 180 FVHITRNQPL EGFTLTKLLW VKQNEPDIWA KAKYFVLPKD YVRYRMTGNL AMDYSDATGT 190 200 210 220 230 240 VLLDVAKGEW SQKICAALDI PMSMCPPLIK SIDLAGTVTP AYAEFSGLTT DTKVFGGAAD 250 260 270 280 290 300 NAAGAVGAGI LHPNMVLSSI GTSGVVLKYE DNADVNYHGV LQFEDHAIPD KFYSMGVTLA 310 320 330 340 350 360 AGYSFTWFKK TFAPAEDFTD VVASAAKSTV GANGLLYTPY IVGERAPYAD ADIRGSFTGV 370 380 390 400 410 420 DGTHQRYDFV RAVLEGIIFS FRDLFDIYEE NGGDFDTVVS IGGGAKSPLW LQIQADIFNR 430 440 450 460 470 480 KVVSLTNEQG PGMGAAMIAA TGLGWFDSLQ DCAETFVHFG KAYEPNPDNV KKYEKMHAIY 490 500 KQVYQQTKTI SEQLLDYRRA EL

References

[1]	"Molecular cloning and functional expression in Lactobacillus plantarum 80 of xylT, encoding the D-xylose-H+ symporter of Lactobacillus brevis." Chaillou S., Bor Y.-C., Batt C.A., Postma P.W., Pouwels P.H. Appl. Environ. Microbiol. 64:4720-4728(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], INDUCTION.
[2]	"Cloning and sequencing the Lactobacillus brevis gene encoding xylose isomerase." Bor Y.-C., Moraes C., Lee S.-P., Crosby W.L., Sinskey A.J., Batt C.A. Gene 114:127-131(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-121.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF045552 Genomic DNA. Translation: AAC95126.1. M84564 Genomic DNA. No translation available.
PIR	JC1138.
3D structure databases
ProteinModelPortal	P35850.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR018485. Carb_kinase_FGGY_C. IPR018483. Carb_kinase_FGGY_CS. IPR018484. Carb_kinase_FGGY_N. IPR006000. Xylulokinase. [Graphical view]
Pfam	PF02782. FGGY_C. 1 hit. PF00370. FGGY_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR01312. XylB. 1 hit.
PROSITE	PS00933. FGGY_KINASES_1. 1 hit. PS00445. FGGY_KINASES_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYLB_LACBR

Accession

Primary (citable) accession number: P35850

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 1, 1994
Last sequence update:	August 14, 2001
Last modified:	April 3, 2013
This is version 51 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program