Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P35842

- PPAB_YEAST

UniProt

P35842 - PPAB_YEAST

Protein

Acid phosphatase PHO11

Gene

PHO11

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 115 (01 Oct 2014)
      Sequence version 1 (01 Jun 1994)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    A phosphate monoester + H2O = an alcohol + phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei75 – 751NucleophileBy similarity
    Active sitei338 – 3381Proton donorBy similarity

    GO - Molecular functioni

    1. acid phosphatase activity Source: SGD

    GO - Biological processi

    1. dephosphorylation Source: GOC
    2. phosphate-containing compound metabolic process Source: SGD

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciYEAST:YAR071W-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acid phosphatase PHO11 (EC:3.1.3.2)
    Alternative name(s):
    P56
    Gene namesi
    Name:PHO11
    Ordered Locus Names:YAR071W
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome I

    Organism-specific databases

    CYGDiYAR071w.
    SGDiS000000094. PHO11.

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: SGD

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1717By similarityAdd
    BLAST
    Chaini18 – 467450Acid phosphatase PHO11PRO_0000023956Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi97 – 971N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi162 – 1621N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi192 – 1921N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi250 – 2501N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi315 – 3151N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi356 – 3561N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi390 – 3901N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi439 – 4391N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi445 – 4451N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi461 – 4611N-linked (GlcNAc...)Sequence Analysis

    Post-translational modificationi

    Glycosylated during secretion across the membrane.

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    MaxQBiP35842.

    Expressioni

    Inductioni

    S.cerevisiae has 2 types of acid phosphatase: one is constitutive and the other is repressible by inorganic phosphate.

    Gene expression databases

    GenevestigatoriP35842.

    Interactioni

    Protein-protein interaction databases

    BioGridi31819. 8 interactions.
    DIPiDIP-4589N.
    IntActiP35842. 1 interaction.
    MINTiMINT-536024.
    STRINGi4932.YAR071W.

    Structurei

    3D structure databases

    ProteinModelPortaliP35842.
    SMRiP35842. Positions 37-457.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the histidine acid phosphatase family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    GeneTreeiENSGT00510000050349.
    HOGENOMiHOG000189191.
    KOiK01078.
    OrthoDBiEOG7TQV9N.

    Family and domain databases

    Gene3Di3.40.50.1240. 1 hit.
    InterProiIPR000560. His_Pase_superF_clade-2.
    IPR029033. His_PPase_superfam.
    IPR016274. Histidine_acid_Pase_euk.
    [Graphical view]
    PfamiPF00328. His_Phos_2. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000894. Acid_phosphatase. 1 hit.
    SUPFAMiSSF53254. SSF53254. 1 hit.
    PROSITEiPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
    PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P35842-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLKSAVYSIL AASLVNAGTI PLGKLSDIDK IGTQTEIFPF LGGSGPYYSF    50
    PGDYGISRDL PESCEMKQVQ MVGRHGERYP TVSKAKSIMT TWYKLSNYTG 100
    QFSGALSFLN DDYEFFIRDT KNLEMETTLA NSVNVLNPYT GEMNAKRHAR 150
    DFLAQYGYMV ENQTSFAVFT SNSNRCHDTA QYFIDGLGDK FNISLQTISE 200
    AESAGANTLS AHHSCPAWDD DVNDDILKKY DTKYLSGIAK RLNKENKGLN 250
    LTSSDANTFF AWCAYEINAR GYSDICNIFT KDELVRFSYG QDLETYYQTG 300
    PGYDVVRSVG ANLFNASVKL LKESEVQDQK VWLSFTHDTD ILNYLTTIGI 350
    IDDKNNLTAE HVPFMENTFH RSWYVPQGAR VYTEKFQCSN DTYVRYVIND 400
    AVVPIETCST GPGFSCEIND FYDYAEKRVA GTDFLKVCNV SSVSNSTELT 450
    FFWDWNTKHY NDTLLKQ 467
    Length:467
    Mass (Da):52,758
    Last modified:June 1, 1994 - v1
    Checksum:iAECDC1C046B326C3
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti17 – 171A → L in AAA73479. 1 PublicationCurated
    Sequence conflicti82 – 832VS → AR in AAA73479. 1 PublicationCurated
    Sequence conflicti150 – 1501R → H in AAA73479. 1 PublicationCurated
    Sequence conflicti354 – 3541K → Q in AAA73479. 1 PublicationCurated
    Sequence conflicti423 – 4231D → G in AAA73479. 1 PublicationCurated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U19789 Genomic DNA. Translation: AAA73479.1.
    L28920 Genomic DNA. Translation: AAC09508.1.
    BK006935 Genomic DNA. Translation: DAA07011.1.
    PIRiS53476.
    RefSeqiNP_009434.1. NM_001178239.1.

    Genome annotation databases

    EnsemblFungiiYAR071W; YAR071W; YAR071W.
    GeneIDi851299.
    KEGGisce:YAR071W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U19789 Genomic DNA. Translation: AAA73479.1 .
    L28920 Genomic DNA. Translation: AAC09508.1 .
    BK006935 Genomic DNA. Translation: DAA07011.1 .
    PIRi S53476.
    RefSeqi NP_009434.1. NM_001178239.1.

    3D structure databases

    ProteinModelPortali P35842.
    SMRi P35842. Positions 37-457.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 31819. 8 interactions.
    DIPi DIP-4589N.
    IntActi P35842. 1 interaction.
    MINTi MINT-536024.
    STRINGi 4932.YAR071W.

    Proteomic databases

    MaxQBi P35842.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YAR071W ; YAR071W ; YAR071W .
    GeneIDi 851299.
    KEGGi sce:YAR071W.

    Organism-specific databases

    CYGDi YAR071w.
    SGDi S000000094. PHO11.

    Phylogenomic databases

    GeneTreei ENSGT00510000050349.
    HOGENOMi HOG000189191.
    KOi K01078.
    OrthoDBi EOG7TQV9N.

    Enzyme and pathway databases

    BioCyci YEAST:YAR071W-MONOMER.

    Miscellaneous databases

    NextBioi 968307.

    Gene expression databases

    Genevestigatori P35842.

    Family and domain databases

    Gene3Di 3.40.50.1240. 1 hit.
    InterProi IPR000560. His_Pase_superF_clade-2.
    IPR029033. His_PPase_superfam.
    IPR016274. Histidine_acid_Pase_euk.
    [Graphical view ]
    Pfami PF00328. His_Phos_2. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000894. Acid_phosphatase. 1 hit.
    SUPFAMi SSF53254. SSF53254. 1 hit.
    PROSITEi PS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
    PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The primary structure of acid phosphatase gene PHO11 in S. cerevisiae and comparison with other gene families."
      Chen J.Y., Gong Y.I., Ao S.Z.
      Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao 21:437-444(1989)
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Sequencing of chromosome I of Saccharomyces cerevisiae: analysis of the 52 Kbp CDC15-FLO1-PHO11-YAR074 region."
      Bussey H., Keng T., Storms R.K., Vo D., Zhong W., Fortin N., Barton A.B., Kaback D.B., Clark M.W.
      Submitted (FEB-1994) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204511 / S288c / AB972.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiPPAB_YEAST
    AccessioniPrimary (citable) accession number: P35842
    Secondary accession number(s): D6VPP1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 1, 1994
    Last sequence update: June 1, 1994
    Last modified: October 1, 2014
    This is version 115 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 1460 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome I
      Yeast (Saccharomyces cerevisiae) chromosome I: entries and gene names

    External Data

    Dasty 3