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P35818 (GSPD_PSEAE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 98. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Type II secretion system protein D

Short name=T2SS protein D
Alternative name(s):
General secretion pathway protein D
Gene names
Name:xcpQ
Ordered Locus Names:PA3105
OrganismPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) [Reference proteome] [HAMAP]
Taxonomic identifier208964 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length658 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins By similarity.

Subcellular location

Cell outer membrane; Peripheral membrane protein Potential.

Sequence similarities

Belongs to the GSP D family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3434 Potential
Chain35 – 658624Type II secretion system protein D
PRO_0000013104

Secondary structure

........................................... 658
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P35818 [UniParc].

Last modified June 1, 1994. Version 1.
Checksum: EC2F81FD1A185D50

FASTA65869,953
        10         20         30         40         50         60 
MSQPLLRALF APSSRSYVPA VLLSLALGIQ AAHAENSGGN AFVPAGNQQE AHWTINLKDA 

        70         80         90        100        110        120 
DIREFIDQIS EITGETFVVD PRVKGQVSVV SKAQLSLSEV YQLFLSVMST HGFTVVAQGD 

       130        140        150        160        170        180 
QARIVPNAEA KTEAGGGQSA PDRLETRVIQ VQQSPVSELI PLIRPLVPQY GHLAAVPSAN 

       190        200        210        220        230        240 
ALIISDRSAN IARIEDVIRQ LDQKGSHDYS VINLRYGWVM DAAEVLNNAM SRGQAKGAAG 

       250        260        270        280        290        300 
AQVIADARTN RLIILGPPQA RAKLVQLAQS LDTPTARSAN TRVIRLRHND AKTLAETLGQ 

       310        320        330        340        350        360 
ISEGMKNNGG QGGEQTGGGR PSNILIRADE STNALVLLAD PDTVNALEDI VRQLDVPRAQ 

       370        380        390        400        410        420 
VLVEAAIVEI SGDIQDAVGV QWAINKGGMG GTKTNFANTG LSIGTLLQSL ESNKAPESIP 

       430        440        450        460        470        480 
DGAIVGIGSS SFGALVTALS ANTKSNLLST PSLLTLDNQK AEILVGQNVP FQTGSYTTNS 

       490        500        510        520        530        540 
EGSSNPFTTV ERKDIGVSLK VTPHINDGAA LRLEIEQEIS ALLPNAQQRN NTDLITSKRS 

       550        560        570        580        590        600 
IKSTILAENG QVIVIGGLIQ DDVSQAESKV PLLGDIPLLG RLFRSTKDTH TKRNLMVFLR 

       610        620        630        640        650 
PTVVRDSAGL AALSGKKYSD IRVIDGTRGP EGRPSILPTN ANQLFDGQAV DLRELMTE 

« Hide

References

« Hide 'large scale' references
[1]"Xcp-mediated protein secretion in Pseudomonas aeruginosa: identification of two additional genes and evidence for regulation of xcp gene expression."
Akrim M., Bally M., Ball G., Tommassen J., Teerink H., Filloux A., Lazdunski A.
Mol. Microbiol. 10:431-443(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
[2]"Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen."
Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P., Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M., Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y., Brody L.L., Coulter S.N., Folger K.R. expand/collapse author list , Kas A., Larbig K., Lim R.M., Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J., Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.
Nature 406:959-964(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X68594 Genomic DNA. Translation: CAA48582.1.
AE004091 Genomic DNA. Translation: AAG06493.1.
PIRS39653.
RefSeqNP_251795.1. NC_002516.2.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4E9JX-ray2.03A/B35-277[»]
4EC5X-ray2.20A/B35-277[»]
ProteinModelPortalP35818.
SMRP35818. Positions 41-273, 323-356.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING208964.PA3105.

Protein family/group databases

TCDB1.B.22.1.2. the outer bacterial membrane secretin (secretin) family.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID880114.
KEGGpae:PA3105.
PATRIC19840783. VBIPseAer58763_3257.

Organism-specific databases

PseudoCAPPA3105.

Phylogenomic databases

eggNOGCOG1450.
HOGENOMHOG000253751.
KOK02453.
OMADMSEYEV.
OrthoDBEOG6423BN.
ProtClustDBCLSK866843.

Family and domain databases

InterProIPR001775. GspD/PilQ.
IPR005644. NolW-like.
IPR004846. T2SS/T3SS.
IPR013356. T2SS_GspD.
IPR004845. T2SS_GspD_CS.
[Graphical view]
PfamPF00263. Secretin. 1 hit.
PF03958. Secretin_N. 3 hits.
[Graphical view]
PRINTSPR00811. BCTERIALGSPD.
TIGRFAMsTIGR02517. type_II_gspD. 1 hit.
PROSITEPS00875. T2SP_D. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGSPD_PSEAE
AccessionPrimary (citable) accession number: P35818
Secondary accession number(s): Q9HZB2
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: April 16, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references