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Protein

Endo-1,4-beta-xylanase C

Gene

xynC

Organism
Fibrobacter succinogenes (strain ATCC 19169 / S85)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Cleaves xylans with the production of xylose, xylobiose and xylo-oligosaccharides.

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.

Pathway: xylan degradation

This protein is involved in the pathway xylan degradation, which is part of Glycan degradation.
View all proteins of this organism that are known to be involved in the pathway xylan degradation and in Glycan degradation.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei142 – 1421NucleophilePROSITE-ProRule annotation
Active sitei237 – 2371Proton donorPROSITE-ProRule annotation
Active sitei409 – 4091NucleophilePROSITE-ProRule annotation
Active sitei501 – 5011Proton donorPROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation, Xylan degradation

Enzyme and pathway databases

UniPathwayiUPA00114.

Protein family/group databases

CAZyiGH11. Glycoside Hydrolase Family 11.
mycoCLAPiXYN11C_FIBSU.

Names & Taxonomyi

Protein namesi
Recommended name:
Endo-1,4-beta-xylanase C (EC:3.2.1.8)
Short name:
Xylanase C
Alternative name(s):
1,4-beta-D-xylan xylanohydrolase C
Gene namesi
Name:xynC
Ordered Locus Names:Fisuc_0362, FSU_0777
OrganismiFibrobacter succinogenes (strain ATCC 19169 / S85)
Taxonomic identifieri59374 [NCBI]
Taxonomic lineageiBacteriaFibrobacteresFibrobacteralesFibrobacteraceaeFibrobacter
ProteomesiUP000000517 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 25251 PublicationAdd
BLAST
Chaini26 – 608583Endo-1,4-beta-xylanase CPRO_0000008006Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi59374.Fisuc_0362.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni26 – 262237Xylanase domain 1Add
BLAST
Regioni286 – 529244Xylanase domain 2Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi263 – 28523Ser-rich (linker)Add
BLAST
Compositional biasi530 – 54314Ser-rich (linker)Add
BLAST

Sequence similaritiesi

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiNOG05353.
OrthoDBiEOG63VBWG.

Family and domain databases

Gene3Di2.60.120.180. 2 hits.
InterProiIPR013320. ConA-like_dom.
IPR001137. Glyco_hydro_11.
IPR013319. Glyco_hydro_11/12.
IPR018208. Glyco_hydro_11_AS.
[Graphical view]
PfamiPF00457. Glyco_hydro_11. 2 hits.
[Graphical view]
PRINTSiPR00911. GLHYDRLASE11.
SUPFAMiSSF49899. SSF49899. 2 hits.
PROSITEiPS00776. GLYCOSYL_HYDROL_F11_1. 1 hit.
PS00777. GLYCOSYL_HYDROL_F11_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P35811-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTFSVTKSS VVFAMALGMA STAFAQDFCS NAQHSGQKVT ITSNQTGKIG
60 70 80 90 100
DIGYELWDEN GHGGSATFYS DGSMDCNITG AKDYLCRAGL SLGSNKTYKE
110 120 130 140 150
LGGDMIAEFK LVKSGAQNVG YSYIGIYGWM EGVSGTPSQL VEYYVIDNTL
160 170 180 190 200
ANDMPGSWIG NERKGTITVD GGTYTVYRNT RTGPAIKNSG NVTFYQYFSV
210 220 230 240 250
RTSPRDCGTI NISEHMRQWE KMGLTMGKLY EAKVLGEAGN VNGEVRGGHM
260 270 280 290 300
DFPHAKVYVK NGSDPVSSSS VKSSSSTDAP KSSSSKGNGN VSGKIDACKD
310 320 330 340 350
VMGHEGKETR TQGQNNSSVT GNVGSSPYHY EIWYQGGNNS MTFYDNGTYK
360 370 380 390 400
ASWNGTNDFL ARVGFKYDEK HTYEELGPID AYYKWSKQGS AGGYNYIGIY
410 420 430 440 450
GWTVDPLVEY YIVDDWFNKP GANLLGQRKG EFTVDGDTYE IWQNTRVQQP
460 470 480 490 500
SIKGTQTFPQ YFSVRKSARS CGHIDITAHM KKWEELGMKM GKMYEAKVLV
510 520 530 540 550
EAGGGSGSFD VTYFKMTDKA HPLAQPEPES SSSEAKVESS SSTVALHAAP
560 570 580 590 600
KMELKSGNFQ VFDMQGRFLG TVKLDAGASV AQVLKANFKN AGIYMVKQGN

FMQRVAVK
Length:608
Mass (Da):66,403
Last modified:January 19, 2010 - v2
Checksum:iBA5653D842798DC4
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti175 – 1751T → I in AAA21848 (PubMed:8244936).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U01037 Genomic DNA. Translation: AAA21848.1.
CP001792 Genomic DNA. Translation: ACX73974.1.
CP002158 Genomic DNA. Translation: ADL26842.1.
PIRiB53295.
RefSeqiWP_012820204.1. NC_017448.1.
YP_003248456.1. NC_013410.1.
YP_005820872.1. NC_017448.1.

Genome annotation databases

EnsemblBacteriaiACX73974; ACX73974; Fisuc_0362.
ADL26842; ADL26842; FSU_0777.
KEGGifsc:FSU_0777.
fsu:Fisuc_0362.
PATRICi32140497. VBIFibSuc28982_0353.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U01037 Genomic DNA. Translation: AAA21848.1.
CP001792 Genomic DNA. Translation: ACX73974.1.
CP002158 Genomic DNA. Translation: ADL26842.1.
PIRiB53295.
RefSeqiWP_012820204.1. NC_017448.1.
YP_003248456.1. NC_013410.1.
YP_005820872.1. NC_017448.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi59374.Fisuc_0362.

Protein family/group databases

CAZyiGH11. Glycoside Hydrolase Family 11.
mycoCLAPiXYN11C_FIBSU.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACX73974; ACX73974; Fisuc_0362.
ADL26842; ADL26842; FSU_0777.
KEGGifsc:FSU_0777.
fsu:Fisuc_0362.
PATRICi32140497. VBIFibSuc28982_0353.

Phylogenomic databases

eggNOGiNOG05353.
OrthoDBiEOG63VBWG.

Enzyme and pathway databases

UniPathwayiUPA00114.

Family and domain databases

Gene3Di2.60.120.180. 2 hits.
InterProiIPR013320. ConA-like_dom.
IPR001137. Glyco_hydro_11.
IPR013319. Glyco_hydro_11/12.
IPR018208. Glyco_hydro_11_AS.
[Graphical view]
PfamiPF00457. Glyco_hydro_11. 2 hits.
[Graphical view]
PRINTSiPR00911. GLHYDRLASE11.
SUPFAMiSSF49899. SSF49899. 2 hits.
PROSITEiPS00776. GLYCOSYL_HYDROL_F11_1. 1 hit.
PS00777. GLYCOSYL_HYDROL_F11_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The xynC gene from Fibrobacter succinogenes S85 codes for a xylanase with two similar catalytic domains."
    Paradis F.W., Zhu H., Krell P.J., Phillips J.P., Forsberg C.W.
    J. Bacteriol. 175:7666-7672(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 26-41.
  2. "Complete sequence of Fibrobacter succinogenes subsp. succinogenes S85."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Weimer P.J.
    , Stevenson D.M., Boyum J., Brumm P.I., Mead D.
    Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 19169 / S85.
  3. "Complete sequence of Fibrobacter succinogenes subsp. succinogenes S85."
    Durkin A.S., Nelson K.E., Morrison M., Forsberg C.W., Wilson D.B., Russell J.B., Cann I.K.O., Mackie R.I., White B.A.
    Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 19169 / S85.

Entry informationi

Entry nameiXYNC_FIBSS
AccessioniPrimary (citable) accession number: P35811
Secondary accession number(s): C9RKP6, D9S812
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: January 19, 2010
Last modified: June 24, 2015
This is version 85 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.