Reviewed, UniProtKB/Swiss-Prot P35811 (XYNC_FIBSU)

Names and origin

Protein names

Recommended name:
    Endo-1,4-beta-xylanase C
      Short name=Xylanase C
    EC=3.2.1.8
Alternative name(s):
    1,4-beta-D-xylan xylanohydrolase C

Gene names

Name:

xynC

Organism

Fibrobacter succinogenes (Bacteroides succinogenes)

Taxonomic identifier

833 [NCBI]

Taxonomic lineage

Bacteria › Fibrobacteres › Fibrobacterales › Fibrobacteraceae › Fibrobacter

Protein attributes

Sequence length	608 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Cleaves xylans with the production of xylose, xylobiose and xylo-oligosaccharides.
Catalytic activity	Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
Pathway	Glycan degradation; xylan degradation.
Sequence similarities	Belongs to the glycosyl hydrolase 11 (cellulase G) family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Cellulose degradation Polysaccharide degradation Xylan degradation
Domain	Repeat Signal
Molecular function	Glycosidase Hydrolase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	cellulose catabolic process Inferred from electronic annotation. Source: UniProtKB-KW xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	endo-1,4-beta-xylanase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 25	25	Ref.1
	Chain	26 – 608	583	Endo-1,4-beta-xylanase C		PRO_0000008006
Regions
	Region	26 – 262	237	Xylanase domain 1
	Region	286 – 529	244	Xylanase domain 2
	Compositional bias	263 – 285	23	Ser-rich (linker)
	Compositional bias	530 – 543	14	Ser-rich (linker)
Sites
	Active site	142	1	Nucleophile By similarity
	Active site	237	1	Proton donor By similarity
	Active site	409	1	Nucleophile By similarity
	Active site	501	1	Proton donor By similarity

Sequences

	Sequence		Length	Mass (Da)
	P35811-1 [UniParc]. Last modified June 1, 1994. Version 1. Checksum: 7FA338016F5857CE	FASTA	608	66,415
	10 20 30 40 50 60 MKTFSVTKSS VVFAMALGMA STAFAQDFCS NAQHSGQKVT ITSNQTGKIG DIGYELWDEN 70 80 90 100 110 120 GHGGSATFYS DGSMDCNITG AKDYLCRAGL SLGSNKTYKE LGGDMIAEFK LVKSGAQNVG 130 140 150 160 170 180 YSYIGIYGWM EGVSGTPSQL VEYYVIDNTL ANDMPGSWIG NERKGTITVD GGTYIVYRNT 190 200 210 220 230 240 RTGPAIKNSG NVTFYQYFSV RTSPRDCGTI NISEHMRQWE KMGLTMGKLY EAKVLGEAGN 250 260 270 280 290 300 VNGEVRGGHM DFPHAKVYVK NGSDPVSSSS VKSSSSTDAP KSSSSKGNGN VSGKIDACKD 310 320 330 340 350 360 VMGHEGKETR TQGQNNSSVT GNVGSSPYHY EIWYQGGNNS MTFYDNGTYK ASWNGTNDFL 370 380 390 400 410 420 ARVGFKYDEK HTYEELGPID AYYKWSKQGS AGGYNYIGIY GWTVDPLVEY YIVDDWFNKP 430 440 450 460 470 480 GANLLGQRKG EFTVDGDTYE IWQNTRVQQP SIKGTQTFPQ YFSVRKSARS CGHIDITAHM 490 500 510 520 530 540 KKWEELGMKM GKMYEAKVLV EAGGGSGSFD VTYFKMTDKA HPLAQPEPES SSSEAKVESS 550 560 570 580 590 600 SSTVALHAAP KMELKSGNFQ VFDMQGRFLG TVKLDAGASV AQVLKANFKN AGIYMVKQGN FMQRVAVK

References

[1]

"The xynC gene from Fibrobacter succinogenes S85 codes for a xylanase with two similar catalytic domains." Paradis F.W., Zhu H., Krell P.J., Phillips J.P., Forsberg C.W. J. Bacteriol. 175:7666-7672(1993) [PubMed: 8244936] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 26-41. Strain: S85 / ATCC 19169.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U01037 Genomic DNA. Translation: AAA21848.1.
PIR	B53295.
3D structure databases
HSSP	HSSP built from PDB template 1XYN based on UniProtKB P36218.
ModBase	Search...
Protein family/group databases
CAZy	GH11. Glycoside Hydrolase Family 11.
Enzyme and pathway databases
BRENDA	3.2.1.8. 15235.
Family and domain databases
InterPro	IPR001137. Glyco_hydro_11. IPR013319. Glyco_hydro_11/12_cat. IPR018208. Glyco_hydro_11_AS. [Graphical view]
Gene3D	G3DSA:2.60.120.180. Glyco_hydro_11/12_cat. 2 hits.
Pfam	PF00457. Glyco_hydro_11. 2 hits. [Graphical view]
PRINTS	PR00911. GLHYDRLASE11.
PROSITE	PS00776. GLYCOSYL_HYDROL_F11_1. 1 hit. PS00777. GLYCOSYL_HYDROL_F11_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYNC_FIBSU

Accession

Primary (citable) accession number: P35811

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 1, 1994
Last sequence update:	June 1, 1994
Last modified:	April 14, 2009
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)