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Protein

Protein InvG

Gene

invG

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Involved in the invasion of the cells of the intestinal epithelium. Could be necessary for the export of invasion related determinants.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport, Virulence

Protein family/group databases

TCDBi1.B.22.3.2. the outer bacterial membrane secretin (secretin) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein InvG
Gene namesi
Name:invG
Ordered Locus Names:STM2898
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001014 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 14Sequence analysisAdd BLAST14
ChainiPRO_000001311115 – 562Protein InvGAdd BLAST548

Proteomic databases

PaxDbiP35672.
PRIDEiP35672.

Interactioni

Protein-protein interaction databases

DIPiDIP-48517N.
STRINGi99287.STM2898.

Structurei

Secondary structure

1562
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi35 – 41Combined sources7
Helixi42 – 49Combined sources8
Helixi50 – 52Combined sources3
Beta strandi57 – 59Combined sources3
Helixi61 – 64Combined sources4
Beta strandi67 – 72Combined sources6
Helixi77 – 88Combined sources12
Beta strandi90 – 94Combined sources5
Beta strandi99 – 103Combined sources5
Helixi104 – 106Combined sources3
Beta strandi108 – 113Combined sources6
Helixi119 – 128Combined sources10
Beta strandi144 – 151Combined sources8
Helixi153 – 169Combined sources17

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2Y9Kelectron microscopy8.30A/B/C/D/E/F/G/H/I/J/K/L/M/N/O34-170[»]
3J1Velectron microscopy-A/B/C/D/E/F/G/H/I/J/K/L/M/N/O22-178[»]
4G08X-ray1.80A22-178[»]
SMRiP35672.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP35672.

Family & Domainsi

Sequence similaritiesi

Belongs to the GSP D family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105K44. Bacteria.
COG1450. LUCA.
HOGENOMiHOG000219449.
KOiK03219.
OMAiANADEMF.
PhylomeDBiP35672.

Family and domain databases

InterProiIPR005644. NolW-like.
IPR004846. T2SS/T3SS.
IPR004845. T2SS_GspD_CS.
IPR003522. T3SS_OM_pore_YscC.
[Graphical view]
PfamiPF00263. Secretin. 1 hit.
PF03958. Secretin_N. 1 hit.
[Graphical view]
PRINTSiPR01337. TYPE3OMGPROT.
TIGRFAMsiTIGR02516. type_III_yscC. 1 hit.
PROSITEiPS00875. T2SP_D. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P35672-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTHILLARV LACAALVLVT PGYSSEKIPV TGSGFVAKDD SLRTFFDAMA
60 70 80 90 100
LQLKEPVIVS KMAARKKITG NFEFHDPNAL LEKLSLQLGL IWYFDGQAIY
110 120 130 140 150
IYDASEMRNA VVSLRNVSLN EFNNFLKRSG LYNKNYPLRG DNRKGTFYVS
160 170 180 190 200
GPPVYVDMVV NAATMMDKQN DGIELGRQKI GVMRLNNTFV GDRTYNLRDQ
210 220 230 240 250
KMVIPGIATA IERLLQGEEQ PLGNIVSSEP PAMPAFSANG EKGKAANYAG
260 270 280 290 300
GMSLQEALKQ NAAAGNIKIV AYPDTNSLLV KGTAEQVHFI EMLVKALDVA
310 320 330 340 350
KRHVELSLWI VDLNKSDLER LGTSWSGSIT IGDKLGVSLN QSSISTLDGS
360 370 380 390 400
RFIAAVNALE EKKQATVVSR PVLLTQENVP AIFDNNRTFY TKLIGERNVA
410 420 430 440 450
LEHVTYGTMI RVLPRFSADG QIEMSLDIED GNDKTPQSDT TTSVDALPEV
460 470 480 490 500
GRTLISTIAR VPHGKSLLVG GYTRDANTDT VQSIPFLGKL PLIGSLFRYS
510 520 530 540 550
SKNKSNVVRV FMIEPKEIVD PLTPDASESV NNILKQSGAW SGDDKLQKWV
560
RVYLDRGQEA IK
Length:562
Mass (Da):61,766
Last modified:January 23, 2002 - v3
Checksum:i8022905BE256058D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti12A → R in AAA74040 (PubMed:7997169).Curated1
Sequence conflicti121E → Q in AAA74040 (PubMed:7997169).Curated1
Sequence conflicti197 – 205LRDQKMVIP → CAIRKWLFR in AAA74040 (PubMed:7997169).Curated9
Sequence conflicti232 – 240AMPAFSANG → RCQRFQRM in AAA74040 (PubMed:7997169).Curated9
Sequence conflicti243G → S in AAA74040 (PubMed:7997169).Curated1
Sequence conflicti262 – 264AAA → KPAEQ in AAA74040 (PubMed:7997169).Curated3
Sequence conflicti328S → T in CAA53049 (PubMed:7868245).Curated1
Sequence conflicti328S → T in AAA74040 (PubMed:7997169).Curated1
Sequence conflicti329I → V in AAA74040 (PubMed:7997169).Curated1
Sequence conflicti370 – 380RPVLLTQENVP → APGITSSGKCS in AAA74040 (PubMed:7997169).CuratedAdd BLAST11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X75302 Genomic DNA. Translation: CAA53049.1.
U08280 Genomic DNA. Translation: AAA74040.1.
AE006468 Genomic DNA. Translation: AAL21778.1.
PIRiS54420.
RefSeqiNP_461819.1. NC_003197.1.
WP_000848113.1. NC_003197.1.

Genome annotation databases

EnsemblBacteriaiAAL21778; AAL21778; STM2898.
GeneIDi1254421.
KEGGistm:STM2898.
PATRICi32384484. VBISalEnt20916_3054.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X75302 Genomic DNA. Translation: CAA53049.1.
U08280 Genomic DNA. Translation: AAA74040.1.
AE006468 Genomic DNA. Translation: AAL21778.1.
PIRiS54420.
RefSeqiNP_461819.1. NC_003197.1.
WP_000848113.1. NC_003197.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2Y9Kelectron microscopy8.30A/B/C/D/E/F/G/H/I/J/K/L/M/N/O34-170[»]
3J1Velectron microscopy-A/B/C/D/E/F/G/H/I/J/K/L/M/N/O22-178[»]
4G08X-ray1.80A22-178[»]
SMRiP35672.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-48517N.
STRINGi99287.STM2898.

Protein family/group databases

TCDBi1.B.22.3.2. the outer bacterial membrane secretin (secretin) family.

Proteomic databases

PaxDbiP35672.
PRIDEiP35672.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL21778; AAL21778; STM2898.
GeneIDi1254421.
KEGGistm:STM2898.
PATRICi32384484. VBISalEnt20916_3054.

Phylogenomic databases

eggNOGiENOG4105K44. Bacteria.
COG1450. LUCA.
HOGENOMiHOG000219449.
KOiK03219.
OMAiANADEMF.
PhylomeDBiP35672.

Miscellaneous databases

EvolutionaryTraceiP35672.

Family and domain databases

InterProiIPR005644. NolW-like.
IPR004846. T2SS/T3SS.
IPR004845. T2SS_GspD_CS.
IPR003522. T3SS_OM_pore_YscC.
[Graphical view]
PfamiPF00263. Secretin. 1 hit.
PF03958. Secretin_N. 1 hit.
[Graphical view]
PRINTSiPR01337. TYPE3OMGPROT.
TIGRFAMsiTIGR02516. type_III_yscC. 1 hit.
PROSITEiPS00875. T2SP_D. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiINVG_SALTY
AccessioniPrimary (citable) accession number: P35672
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: January 23, 2002
Last modified: November 2, 2016
This is version 109 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.