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Protein

Putative ABC transporter ATP-binding protein exp8

Gene

exp8

Organism
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi374 – 381ATPPROSITE-ProRule annotation8

GO - Molecular functioni

Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative ABC transporter ATP-binding protein exp8
Alternative name(s):
Exported protein 8
Gene namesi
Name:exp8
Ordered Locus Names:SP_1839
OrganismiStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Taxonomic identifieri170187 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000000585 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei26 – 46HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei61 – 81HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei135 – 155HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei159 – 179HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei259 – 279HelicalPROSITE-ProRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000923221 – 583Putative ABC transporter ATP-binding protein exp8Add BLAST583

Structurei

3D structure databases

ProteinModelPortaliP35598.
SMRiP35598.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 308ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST284
Domaini341 – 574ABC transporterPROSITE-ProRule annotationAdd BLAST234

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105BZ1. Bacteria.
COG1132. LUCA.
KOiK18890.
OMAiVFITQRL.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00664. ABC_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90123. SSF90123. 1 hit.
PROSITEiView protein in PROSITE
PS50929. ABC_TM1F. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.

Sequencei

Sequence statusi: Complete.

P35598-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQNKQEQWTV LKRLMSYLKP YGLLTFLALS FLLATTVIKS VIPLVASHFI
60 70 80 90 100
DQYLSNLNQL AVTVLLVYYG LYILQTVVQY VGNLLFARVS YSIVRDIRRD
110 120 130 140 150
AFANMEKLGM SYFDKTPAGS IVSRLTNDTE TISDMFSGIL SSFISAVFIF
160 170 180 190 200
LTTLYTMLVL DFRLTALVLL FLPLIFLLVN LYRKKSVKII EKTRSLLSDI
210 220 230 240 250
NSKLAENIEG IRIIQAFNQE KRLQAEFDEI NQEHLVYANR SVALDALFLR
260 270 280 290 300
PAMSLLKLLG YAVLMAYFGY RGFSIGITVG TMYAFIQYIN RLFDPLIEVT
310 320 330 340 350
QNFSTLQTAM VSAGRVFALI DERTYEPLQE NGQAKVQEGN IRFEHVCFSY
360 370 380 390 400
DGKHPILDDI SFSVNKGETI AFVGHTGSGK SSIINVLMRF YEFQSGRVLL
410 420 430 440 450
DDVDIRDFSQ EELRKNIGLV LQEPFLYHGT IKSNIAMYQE TSDEQVQAAA
460 470 480 490 500
AFVDADSFIQ ELPQGYDSPV SERGSSFSTG QRQLLAFART VASQPKILIL
510 520 530 540 550
DEATANIDSE TESLVQASLA KMRQGRTTIA IAHRLSTIQD ANCIYVLDKG
560 570 580
RIIESGTHEE LLALGGTYHK MYSLQAGAMA DTL
Length:583
Mass (Da):65,552
Last modified:September 26, 2001 - v3
Checksum:i59D5FBC886D0CBA0
GO

Sequence cautioni

The sequence AAA26884 differs from that shown. Contaminating sequence. Vector contamination at the N-terminus, a segment of 26 residues, which seems to originate from a pUC-type vector.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti441T → I in AAA26884 (PubMed:7934910).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005672 Genomic DNA. Translation: AAK75912.1.
L20562 Genomic DNA. Translation: AAA26884.1. Different termination.
PIRiG95214.
RefSeqiWP_001180176.1. NZ_AKVY01000001.1.

Genome annotation databases

EnsemblBacteriaiAAK75912; AAK75912; SP_1839.
KEGGispn:SP_1839.

Similar proteinsi

Entry informationi

Entry nameiEXP8_STRPN
AccessioniPrimary (citable) accession number: P35598
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: September 26, 2001
Last modified: July 5, 2017
This is version 123 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families