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Protein

60 kDa chaperonin 1

Gene

groL1

Organism
Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processStress response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperonin 1UniRule annotation
Alternative name(s):
GroEL protein 1UniRule annotation
Protein Cpn60 1UniRule annotation
Gene namesi
Name:groL1UniRule annotation
Synonyms:groEL-AUniRule annotation, groEL1UniRule annotation
Ordered Locus Names:R00792
ORF Names:SMc00913
OrganismiRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Taxonomic identifieri266834 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
Proteomesi
  • UP000001976 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000635001 – 54560 kDa chaperonin 1Add BLAST545

Proteomic databases

PRIDEiP35469.

Expressioni

Inductioni

By heat shock.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi266834.SMc00913.

Structurei

3D structure databases

ProteinModelPortaliP35469.
SMRiP35469.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
KOiK04077.
OMAiCVIKVGA.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR037290. Cpn60/TCP-1_sf.
IPR027409. GroEL-like_apical_dom_sf.
IPR027413. GROEL-like_equatorial_sf.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

P35469-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAKEVKFGR SAREKMLRGV DILADAVKVT LGPKGRNVVI DKSFGAPRIT
60 70 80 90 100
KDGVSVAKEI ELEDKFENMG AQMVREVASK TNDIAGDGTT TATVLAQAIV
110 120 130 140 150
REGAKAVAAG MNPMDLKRGI DLAVAEVVKD LLAKAKKINT SDEVAQVGTI
160 170 180 190 200
SANGEKQIGL DIAEAMQKVG NEGVITVEEA KTAETELEVV EGMQFDRGYL
210 220 230 240 250
SPYFVTNPEK MVADLEDAFI LLHEKKLSNL QAMLPVLEAV VQTGKPLLII
260 270 280 290 300
AEDVEGEALA TLVVNKLRGG LKIAAVKAPG FGDRRKAMLE DIAILTGGTV
310 320 330 340 350
ISEDLGIKLE SVTLDMLGRA KKVSITKENT TIVDGAGQKS DIEGRVAQIK
360 370 380 390 400
AQIEETTSDY DREKLQERLA KLAGGVAVIR VGGATEVEVK EKKDRIDDAL
410 420 430 440 450
NATRAAVQEG IVPGGGVALL RSSVKITVKG ENDDQDAGVN IVRRALQSPA
460 470 480 490 500
RQIVENAGDE ASIVVGKILE KNTDDFGYNA QTGEYGDMIA MGIIDPVKVV
510 520 530 540
RTALQDAASV ASLLITTEAM IAELPKKDAP AMPGGMGGMG GMDMM
Length:545
Mass (Da):57,687
Last modified:May 30, 2000 - v2
Checksum:i4CEF358957E1B45A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti12A → G in AAA26285 (PubMed:8097179).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M94192 Genomic DNA. Translation: AAA26285.1.
U19726 Genomic DNA. Translation: AAA61955.1.
AL591688 Genomic DNA. Translation: CAC45364.1.
PIRiJN0509.
RefSeqiNP_384898.1. NC_003047.1.
WP_010968823.1. NC_003047.1.

Genome annotation databases

EnsemblBacteriaiCAC45364; CAC45364; SMc00913.
GeneIDi1232433.
KEGGisme:SMc00913.
PATRICifig|266834.11.peg.2178.

Similar proteinsi

Entry informationi

Entry nameiCH601_RHIME
AccessioniPrimary (citable) accession number: P35469
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: May 30, 2000
Last modified: November 22, 2017
This is version 112 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families