P35454NEU1_MOUSEOxytocin-neurophysin 1OT-NPIOxytocinOcytocinNeurophysin 1OxtMus musculusMouseEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMusStructure of mouse vasopressin and oxytocin genes.NUCLEOTIDE SEQUENCE [GENOMIC DNA]High-throughput sequence identification of gene coding variants within alcohol-related QTLs.NUCLEOTIDE SEQUENCE [MRNA]Neurophysin 1 specifically binds oxytocin.Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland. Acts by binding to oxytocin receptor (OXTR) (By similarity).Interacts with oxytocin receptor (Ki=1.5 nM) (By similarity). Interacts with vasopressin V1aR/AVPR1A (Ki=37 nM), V1bR/AVPR1B (Ki=222 nM), and V2R/AVPR2 receptors (Ki=823 nM) (By similarity).Belongs to the vasopressin/oxytocin family.AmidationCleavage on pair of basic residuesDisulfide bondHormoneReference proteomeSignalMACPSLACCLLGLLALTSACYIQNCPLGGKRAVLDLDMRKCLPCGPGGKGRCFGPSICCADELGCFVGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAATGICCSPDGCRTDPACDPESAFSER
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