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P35224

- CTNB_URECA

UniProt

P35224 - CTNB_URECA

Protein

Catenin beta

Gene
N/A
Organism
Urechis caupo (Innkeeper worm) (Spoonworm)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (01 Feb 1994)
      Previous versions | rss
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    Functioni

    Binds to the cytoplasmic domain of the cell-cell adhesion molecule E-cadherin, and perhaps to other (membrane) proteins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.

    GO - Biological processi

    1. cell adhesion Source: UniProtKB-KW

    Keywords - Biological processi

    Cell adhesion

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Catenin beta
    Alternative name(s):
    Beta-catenin
    OrganismiUrechis caupo (Innkeeper worm) (Spoonworm)
    Taxonomic identifieri6431 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaLophotrochozoaAnnelidaPolychaetaEchiuraXenopneustaUrechidaeUrechis

    Subcellular locationi

    Cytoplasm By similarity. Cytoplasmcytoskeleton By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. cytoskeleton Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm, Cytoskeleton

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 818818Catenin betaPRO_0000064275Add
    BLAST

    Proteomic databases

    PRIDEiP35224.

    Structurei

    3D structure databases

    ProteinModelPortaliP35224.
    SMRiP35224. Positions 150-705.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati164 – 20340ARM 1Add
    BLAST
    Repeati248 – 28740ARM 2Add
    BLAST
    Repeati412 – 45140ARM 3Add
    BLAST
    Repeati454 – 49542ARM 4Add
    BLAST
    Repeati501 – 54141ARM 5Add
    BLAST
    Repeati543 – 58240ARM 6Add
    BLAST
    Repeati648 – 68740ARM 7Add
    BLAST

    Sequence similaritiesi

    Belongs to the beta-catenin family.Curated
    Contains 7 ARM repeats.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat

    Family and domain databases

    Gene3Di1.25.10.10. 1 hit.
    InterProiIPR011989. ARM-like.
    IPR016024. ARM-type_fold.
    IPR000225. Armadillo.
    IPR013284. Beta-catenin.
    [Graphical view]
    PfamiPF00514. Arm. 4 hits.
    [Graphical view]
    PRINTSiPR01869. BCATNINFAMLY.
    SMARTiSM00185. ARM. 12 hits.
    [Graphical view]
    SUPFAMiSSF48371. SSF48371. 1 hit.
    PROSITEiPS50176. ARM_REPEAT. 9 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P35224-1 [UniParc]FASTAAdd to Basket

    « Hide

    METYQQMNSG SGPRSVGTPQ GQYMDVGEMP PMDAKQQTML WQQNQYMGDS    50
    GIQSGATTQA PPSVSSKHGL DDMDTGEGMD TSRMMFDFDQ GFSTQAFTQE 100
    QVDEMNQQLN QTRSQRVRAA MFPETLEEGV QIPSTQLDPG QPTAVQRLSE 150
    PSQMLKHAVV NLINYQDDAD LATRAIPELT KLLNDEDQVV VSQAAMMVHQ 200
    LSKKEASRHA IMNSPQMVAA LVRAMTNTND LETTRCAAGT LHNLSHHRQG 250
    LLTIFKSGGI PALVKLLSSP VESVLFYAIT TLHNLLLHQE GSKMAVRLAG 300
    GLQKMVLLLQ RNNLKFLAIT TDCLQILAYG NQESKLIILA SGGPGELVRI 350
    MRSYTYEKLL WTTSRVLKVL SVCASNKPAI VEAGSAGPSM HLGHQSQRLV 400
    QNCLWTLRNL SDAATKSSDI EGLLQMLVQL LASNDINIVT CAAGILSNLT 450
    CNNQRNKVTV CQVGGIEALV RTILQAGDRE DITEPAVCAL RHLTSRHGEA 500
    EMAQNAVRLH YGLPVLVKLL HPPSRWPLIK AVVGLIRNLA LCPANHAPLR 550
    EHGAIPRIVQ LLIRAHQDTQ RRATAGSGNT SAYVDGVRME EIVEGTVGAL 600
    HIMAREAHNR AVIRGLNCIS LFAQLLYSPI DNIQRVAAGV LCELAADKEG 650
    AEMIEQEGTT APLTELLHSR NEGVATYAAA VLFRMSEDKP QDYKKRLSVE 700
    LTSSLFRGEQ VPWGEPPGLD DMDSSQLLPE EQGFRGYQGS GPGSVPSGPP 750
    HDMNRQDSMQ GLELGSQQGT AYGSHMPDLG PNTDLHFDPM DGGGSSMGGP 800
    HTPTDPQNQM AAWFDTDL 818
    Length:818
    Mass (Da):89,070
    Last modified:February 1, 1994 - v1
    Checksum:i1DF174BEEF745C1D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L10355 mRNA. Translation: AAA30330.1.
    PIRiS33793.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L10355 mRNA. Translation: AAA30330.1 .
    PIRi S33793.

    3D structure databases

    ProteinModelPortali P35224.
    SMRi P35224. Positions 150-705.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi P35224.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 1.25.10.10. 1 hit.
    InterProi IPR011989. ARM-like.
    IPR016024. ARM-type_fold.
    IPR000225. Armadillo.
    IPR013284. Beta-catenin.
    [Graphical view ]
    Pfami PF00514. Arm. 4 hits.
    [Graphical view ]
    PRINTSi PR01869. BCATNINFAMLY.
    SMARTi SM00185. ARM. 12 hits.
    [Graphical view ]
    SUPFAMi SSF48371. SSF48371. 1 hit.
    PROSITEi PS50176. ARM_REPEAT. 9 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Identification of homologues to beta-catenin/plakoglobin/armadillo in two invertebrates, Urechis caupo and Tripneustes gratilla."
      Rosenthal E.T.
      Biochim. Biophys. Acta 1173:337-341(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiCTNB_URECA
    AccessioniPrimary (citable) accession number: P35224
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1994
    Last sequence update: February 1, 1994
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3