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P35223

- CTNB_TRIGR

UniProt

P35223 - CTNB_TRIGR

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Protein
Catenin beta
Gene
N/A
Organism
Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Binds to the cytoplasmic domain of the cell-cell adhesion molecule E-cadherin, and perhaps to other (membrane) proteins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.

GO - Biological processi

  1. cell adhesion Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Cell adhesion

Names & Taxonomyi

Protein namesi
Recommended name:
Catenin beta
Alternative name(s):
Beta-catenin
OrganismiTripneustes gratilla (Hawaian sea urchin) (Echinus gratilla)
Taxonomic identifieri7673 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEchinodermataEleutherozoaEchinozoaEchinoideaEuechinoideaEchinaceaTemnopleuroidaToxopneustidaeTripneustes

Subcellular locationi

Cytoplasm By similarity. Cytoplasmcytoskeleton By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. cytoskeleton Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 820820Catenin beta
PRO_0000064274Add
BLAST

Proteomic databases

PRIDEiP35223.

Structurei

3D structure databases

ProteinModelPortaliP35223.
SMRiP35223. Positions 143-701.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati157 – 19640ARM 1
Add
BLAST
Repeati199 – 23941ARM 2
Add
BLAST
Repeati241 – 28040ARM 3
Add
BLAST
Repeati283 – 32240ARM 4
Add
BLAST
Repeati367 – 40539ARM 5
Add
BLAST
Repeati406 – 44540ARM 6
Add
BLAST
Repeati448 – 48942ARM 7
Add
BLAST
Repeati495 – 53541ARM 8
Add
BLAST
Repeati603 – 64240ARM 9
Add
BLAST
Repeati644 – 68340ARM 10
Add
BLAST

Sequence similaritiesi

Belongs to the beta-catenin family.
Contains 10 ARM repeats.

Keywords - Domaini

Repeat

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000225. Armadillo.
IPR013284. Beta-catenin.
[Graphical view]
PfamiPF00514. Arm. 4 hits.
[Graphical view]
PRINTSiPR01869. BCATNINFAMLY.
SMARTiSM00185. ARM. 12 hits.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS50176. ARM_REPEAT. 9 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P35223-1 [UniParc]FASTAAdd to Basket

« Hide

MEQARYSNQQ SVNPQQKGFG GPGLQDLPKQ DPMQNTMEWQ HHGYGMDSGF    50
QSSATSHPPS VSSKSRHEDG GEEAQAQGMF EWDAGYGQAY TQEQVDEMNQ 100
QLTQTRSQRV RAAMFPETLE EGVQIPSTQF DPAHPTAVQR LSEPSQMLKH 150
AVVNLINYQD DADLATRAIP ELTKLLNDDD LVVVNQAAMM VHQLSKKEAS 200
RHAIMNSPQM VAALVRAMSN SNDAETTRCA AGTLHNLSHH RAGLLQIFKS 250
GGIPALIKLL SSPVESVLFY AITTLHNLLL HQEGSKMAVR LAGGLQKMVA 300
LLSRNNPKFL AITTDCLQIL AYGNQESKLI ILASGGPAAL VHIMRTYDYE 350
KLLWTTSRVL KVLSVCHNNK PAIVEAGGMS ALGLHLGHHS NRLVQNCLWT 400
LRNLSDCHRG TDDIEPLLQM LVQLLASNDI NVVTCACGIL SNLTCNNSRN 450
KMIVSQMAGV EALVQTLMKA GDREEITEPA VCALRHVTSR HPGAEMGQNT 500
VRLNYGIPVI VKLLHPPSRW PLIKATVGLI RNLALCSANH APLREQGALH 550
RLVQLLMRAH QDTQRRSSMG STGSQGGNYA DGVRMEDIVE GTTGALHILA 600
RDSHNRALIQ GLNCIPLFVQ LLYNNIENIQ RVAAGVLSEL SLEKQGAEMI 650
EQEGATAPLT ELLHSRNEGV ATYAAAVLYR MSDDKPQDYK KRISVELGNS 700
LFRGDSVPWG DPLDMPSDNQ ILPPSSMGGH PPDPGYPQPG SVHSLHSNHG 750
EYRQPPPPMQ GYHDGTGPIE PMMQDLDLGG GGDFGMDPGL PDMGPPASDL 800
NLDSIPPADN TGLAFFDTDL 820
Length:820
Mass (Da):89,361
Last modified:February 1, 1994 - v1
Checksum:i57255E0F57795FD3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L10354 mRNA. Translation: AAA30089.1.
PIRiS33794.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L10354 mRNA. Translation: AAA30089.1 .
PIRi S33794.

3D structure databases

ProteinModelPortali P35223.
SMRi P35223. Positions 143-701.
ModBasei Search...

Proteomic databases

PRIDEi P35223.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 1.25.10.10. 1 hit.
InterProi IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000225. Armadillo.
IPR013284. Beta-catenin.
[Graphical view ]
Pfami PF00514. Arm. 4 hits.
[Graphical view ]
PRINTSi PR01869. BCATNINFAMLY.
SMARTi SM00185. ARM. 12 hits.
[Graphical view ]
SUPFAMi SSF48371. SSF48371. 1 hit.
PROSITEi PS50176. ARM_REPEAT. 9 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Identification of homologues to beta-catenin/plakoglobin/armadillo in two invertebrates, Urechis caupo and Tripneustes gratilla."
    Rosenthal E.T.
    Biochim. Biophys. Acta 1173:337-341(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiCTNB_TRIGR
AccessioniPrimary (citable) accession number: P35223
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: October 16, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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