Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P35223

- CTNB_TRIGR

UniProt

P35223 - CTNB_TRIGR

Protein

Catenin beta

Gene
N/A
Organism
Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (01 Feb 1994)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Binds to the cytoplasmic domain of the cell-cell adhesion molecule E-cadherin, and perhaps to other (membrane) proteins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.

    GO - Biological processi

    1. cell adhesion Source: UniProtKB-KW

    Keywords - Biological processi

    Cell adhesion

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Catenin beta
    Alternative name(s):
    Beta-catenin
    OrganismiTripneustes gratilla (Hawaian sea urchin) (Echinus gratilla)
    Taxonomic identifieri7673 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEchinodermataEleutherozoaEchinozoaEchinoideaEuechinoideaEchinaceaTemnopleuroidaToxopneustidaeTripneustes

    Subcellular locationi

    Cytoplasm By similarity. Cytoplasmcytoskeleton By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. cytoskeleton Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm, Cytoskeleton

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 820820Catenin betaPRO_0000064274Add
    BLAST

    Proteomic databases

    PRIDEiP35223.

    Structurei

    3D structure databases

    ProteinModelPortaliP35223.
    SMRiP35223. Positions 143-701.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati157 – 19640ARM 1Add
    BLAST
    Repeati199 – 23941ARM 2Add
    BLAST
    Repeati241 – 28040ARM 3Add
    BLAST
    Repeati283 – 32240ARM 4Add
    BLAST
    Repeati367 – 40539ARM 5Add
    BLAST
    Repeati406 – 44540ARM 6Add
    BLAST
    Repeati448 – 48942ARM 7Add
    BLAST
    Repeati495 – 53541ARM 8Add
    BLAST
    Repeati603 – 64240ARM 9Add
    BLAST
    Repeati644 – 68340ARM 10Add
    BLAST

    Sequence similaritiesi

    Belongs to the beta-catenin family.Curated
    Contains 10 ARM repeats.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat

    Family and domain databases

    Gene3Di1.25.10.10. 1 hit.
    InterProiIPR011989. ARM-like.
    IPR016024. ARM-type_fold.
    IPR000225. Armadillo.
    IPR013284. Beta-catenin.
    [Graphical view]
    PfamiPF00514. Arm. 4 hits.
    [Graphical view]
    PRINTSiPR01869. BCATNINFAMLY.
    SMARTiSM00185. ARM. 12 hits.
    [Graphical view]
    SUPFAMiSSF48371. SSF48371. 1 hit.
    PROSITEiPS50176. ARM_REPEAT. 9 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P35223-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEQARYSNQQ SVNPQQKGFG GPGLQDLPKQ DPMQNTMEWQ HHGYGMDSGF    50
    QSSATSHPPS VSSKSRHEDG GEEAQAQGMF EWDAGYGQAY TQEQVDEMNQ 100
    QLTQTRSQRV RAAMFPETLE EGVQIPSTQF DPAHPTAVQR LSEPSQMLKH 150
    AVVNLINYQD DADLATRAIP ELTKLLNDDD LVVVNQAAMM VHQLSKKEAS 200
    RHAIMNSPQM VAALVRAMSN SNDAETTRCA AGTLHNLSHH RAGLLQIFKS 250
    GGIPALIKLL SSPVESVLFY AITTLHNLLL HQEGSKMAVR LAGGLQKMVA 300
    LLSRNNPKFL AITTDCLQIL AYGNQESKLI ILASGGPAAL VHIMRTYDYE 350
    KLLWTTSRVL KVLSVCHNNK PAIVEAGGMS ALGLHLGHHS NRLVQNCLWT 400
    LRNLSDCHRG TDDIEPLLQM LVQLLASNDI NVVTCACGIL SNLTCNNSRN 450
    KMIVSQMAGV EALVQTLMKA GDREEITEPA VCALRHVTSR HPGAEMGQNT 500
    VRLNYGIPVI VKLLHPPSRW PLIKATVGLI RNLALCSANH APLREQGALH 550
    RLVQLLMRAH QDTQRRSSMG STGSQGGNYA DGVRMEDIVE GTTGALHILA 600
    RDSHNRALIQ GLNCIPLFVQ LLYNNIENIQ RVAAGVLSEL SLEKQGAEMI 650
    EQEGATAPLT ELLHSRNEGV ATYAAAVLYR MSDDKPQDYK KRISVELGNS 700
    LFRGDSVPWG DPLDMPSDNQ ILPPSSMGGH PPDPGYPQPG SVHSLHSNHG 750
    EYRQPPPPMQ GYHDGTGPIE PMMQDLDLGG GGDFGMDPGL PDMGPPASDL 800
    NLDSIPPADN TGLAFFDTDL 820
    Length:820
    Mass (Da):89,361
    Last modified:February 1, 1994 - v1
    Checksum:i57255E0F57795FD3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L10354 mRNA. Translation: AAA30089.1.
    PIRiS33794.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L10354 mRNA. Translation: AAA30089.1 .
    PIRi S33794.

    3D structure databases

    ProteinModelPortali P35223.
    SMRi P35223. Positions 143-701.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi P35223.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 1.25.10.10. 1 hit.
    InterProi IPR011989. ARM-like.
    IPR016024. ARM-type_fold.
    IPR000225. Armadillo.
    IPR013284. Beta-catenin.
    [Graphical view ]
    Pfami PF00514. Arm. 4 hits.
    [Graphical view ]
    PRINTSi PR01869. BCATNINFAMLY.
    SMARTi SM00185. ARM. 12 hits.
    [Graphical view ]
    SUPFAMi SSF48371. SSF48371. 1 hit.
    PROSITEi PS50176. ARM_REPEAT. 9 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Identification of homologues to beta-catenin/plakoglobin/armadillo in two invertebrates, Urechis caupo and Tripneustes gratilla."
      Rosenthal E.T.
      Biochim. Biophys. Acta 1173:337-341(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiCTNB_TRIGR
    AccessioniPrimary (citable) accession number: P35223
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1994
    Last sequence update: February 1, 1994
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3