Protein SPT23

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

Miscellaneous

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

• cellular response to cold Source: SGD <p>Inferred from Genetic Interaction</p> <p>Used to describe “traditional” genetic interactions such as suppressors and synthetic lethals as well as other techniques such as functional complementation, rescue experiments, or inferences about a gene drawn from the phenotype of a mutation in a different gene.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#igi">GO evidence code guide</a></p> Inferred from genetic interactionⁱ
  • 11855848
• chromatin silencing at silent mating-type cassette Source: SGD <p>Inferred from Genetic Interaction</p> <p>Used to describe “traditional” genetic interactions such as suppressors and synthetic lethals as well as other techniques such as functional complementation, rescue experiments, or inferences about a gene drawn from the phenotype of a mutation in a different gene.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#igi">GO evidence code guide</a></p> Inferred from genetic interactionⁱ
  • 11063674
• positive regulation of transcription from RNA polymerase II promoter Source: SGD <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypeⁱ
  • 11557770
• positive regulation of unsaturated fatty acid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter Source: SGD <p>Inferred from Genetic Interaction</p> <p>Used to describe “traditional” genetic interactions such as suppressors and synthetic lethals as well as other techniques such as functional complementation, rescue experiments, or inferences about a gene drawn from the phenotype of a mutation in a different gene.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#igi">GO evidence code guide</a></p> Inferred from genetic interactionⁱ
  • 9927444

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componentⁱ

• integral component of endoplasmic reticulum membrane Source: SGD <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • 11007476
• nucleus Source: SGD <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • 11007476

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Molecule processing

Amino acid modifications

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMⁱ

Proteomic databases

PTM databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the ‘Sequence’ section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MMSGTGNVSS MLHSYSANIQ HNDGSPDLDL LESELLDIAL LNSGSSLQDP 
        60         70         80         90        100
GLLSLNQEKM ITAGTTTPGK EDEGELRDDI ASLQGLLDRH VQFGRKLPLR 
       110        120        130        140        150
TPYANPLDFI NINPQSLPLS LEIIGLPKVS RVETQMKLSF RIRNAHARKN 
       160        170        180        190        200
FFIHLPSDCI AKDKFFTSSD DPTNLTIPNR DINERTLFLD AFLLCASNNN 
       210        220        230        240        250
SNNFKQTYVC NRCINREKRR ASRRKSGLND NSIWQNNENK RAIIFNSKQL 
       260        270        280        290        300
FIISNNGLSG NSNCINFDLP TRIVCYCRHH KATNGFVVLF LLRDHNGDIL 
       310        320        330        340        350
AKTITDPIMI MDKKNASNTT TPTSTSNAQV SPMTNDTRSF SSPQSDLNFP 
       360        370        380        390        400
SEFPLPSNSK NFVISTNCML DSNCNNNNND NDNKNNIKTN TAMMNNNRHF 
       410        420        430        440        450
PSPNSSSEDS NHSFSDIHFS NNNDNNLHRS LDSWSSTGFN SSSNPALTTL 
       460        470        480        490        500
TSDFSAASAR HTGKRQRSVN EPFMSTPNTF SRLPQKFIDS SKDISNHNSV 
       510        520        530        540        550
PVALNNKPSI QRVIPAQGSI NGGIEVTLLG SKFKQGLIIK FGENIALSSQ 
       560        570        580        590        600
CWNESTMVTY LPPSSKPGPV LVTIVDPSET SMRNNSNSSV STSNSTNDIL 
       610        620        630        640        650
HLNKYTGEKA IFTYVDDTDR QLIELALQIV GLKMNGKLED ARNIAKRIVG 
       660        670        680        690        700
SDSSPSNNNA GLHSQNSSLN SYTNMMRNIN DEQLITEVIK SFKRNNNLST 
       710        720        730        740        750
VNLSMCDVRG RTLLHLAAFN NWYSLVSLLI KYGSHLNDQD LFGFTPLHMA 
       760        770        780        790        800
CINGDLRIIR LLLECNVNIM KKTRNGFIAK QFFLMNYTVN KTRYSNYETS 
       810        820        830        840        850
LFDDILTRLT KNTTGSSDTQ PFERNVSQSS FNSSLFDDDD ADHDYVQERK 
       860        870        880        890        900
YLLADSAALA PEQSNCNDNT SFSILDSDSG YDISDCESSS DEIALEFFNT 
       910        920        930        940        950
HKIKDFSSKP NEIPKTTKTS IEPDGSLWNR MLTRLNDELP KYEDLFPKKP 
       960        970        980        990       1000
KNWELGSKSV EIGPDNSAQM TVDDSQTSSE DDELEALQVG FNTIFSKKQN 
      1010       1020       1030       1040       1050
FQNDKMLLFF WIPLTLVLLL CFTLSNLGKD DDMFHNLSKI VQEYLRIGLA 
      1060       1070       1080 
KVLLGNERMK TSFKMQLSKF QNNNILNDMR VN            

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautionⁱ

Experimental Info

Sequence databases

Genome annotation databases

<p>This section provides links to the UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>). UniRef consists of clusters for UniProtKB sequences (including isoforms) and selected UniParc sequences, in order to obtain complete coverage of the sequence space at resolutions of 100%, 90% and 50% identity.<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ

Documents

1. Yeast
   Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
2. Yeast chromosome XI
   Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names