Reviewed, UniProtKB/Swiss-Prot P35190 (CLG1_YEAST)

Names and origin

Protein names

Recommended name:
    PHO85 cyclin CLG1
Alternative name(s):
    Cyclin-like G1 protein 1

Gene names

Name:	CLG1
Ordered Locus Names:	YGL215W
ORF Names:	G1105

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	452 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Cyclin partner of the cyclin-dependent kinase (CDK) PHO85. Has a role in cell integrity and polarized cell growth together with the other PCL1/PCL2 cyclin family members.
Subunit structure	Forms a cyclin-CDK complex with PHO85.
Sequence similarities	Belongs to the cyclin family. PCL1,2 subfamily.

Ontologies

Keywords
Molecular function	Cyclin
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell cycle Traceable author statement. Source: SGD
Cellular component	cyclin-dependent protein kinase holoenzyme complex Traceable author statement. Source: SGD
Molecular function	cyclin-dependent protein kinase regulator activity Traceable author statement. Source: SGD protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
ECM4	P36156	1	EBI-4762,EBI-2042717
PHO85	P17157	3	EBI-4762,EBI-13327

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 452	452	PHO85 cyclin CLG1		PRO_0000080503
Regions
	Compositional bias	395 – 401	7	Poly-Gln

Sequences

	Sequence		Length	Mass (Da)
	P35190-1 [UniParc]. Last modified February 1, 1994. Version 1. Checksum: 579CAE1C45A2BE84	FASTA	452	51,571
	10 20 30 40 50 60 MANTFKYYPE TMGNSSGYPI SLPFPKGSAT SAVNVARQLP KYLGHVPSQS VHTQLPSMAS 70 80 90 100 110 120 LGYFNQPSST YYAPPAPLQQ HQQPPILPPP GLMYTSNNNS NVIPPPVQMI RDGQQQPQQS 130 140 150 160 170 180 NQVNGGVSEN LDYDISIMSK FIMENAFVAF NANYSTDDQT TDLFFKGISS VLNATRLPSA 190 200 210 220 230 240 TIFLAIDYLF KYINKLSNGI HSIGGNSINI IYQNTMIAFI LANKFNDDKT FTNNSWSQAT 250 260 270 280 290 300 GILINVINDF ERQWLRIFNW ELYDSAFLYF EFVKNFEIFK QNQLKPAVAV PTLLSPIVNV 310 320 330 340 350 360 GDTRNVNFNL KPTSTNNLLS PVSNYETPML MPHNMFSSPS YQSNSRSEFS SMNGYYNYYN 370 380 390 400 410 420 YNQPRLNYYQ QFPNIYSSPI SETQFDYDFY NFSSQQQQQQ QKQHSLLPAA PQLPPPHVHN 430 440 450 QSYGHHLGWK SMDDTINHSR FERNYFPYSA VY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"CLG1, a new cyclin-like gene of Saccharomyces cerevisiae." Matsumoto Y., Wickner R.B. Yeast 9:929-931(1993) [PubMed: 8212900] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"Sequence analysis of 203 kilobases from Saccharomyces cerevisiae chromosome VII." Rieger M., Brueckner M., Schaefer M., Mueller-Auer S. Yeast 13:1077-1090(1997) [PubMed: 9290212] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[3]	"Analysis of 21.7 kb DNA sequence from the left arm of chromosome VII reveals 11 open reading frames: two correspond to new genes." Feuermann M., Simeonava L., Souciet J.-L., Potier S. Yeast 13:475-477(1997) [PubMed: 9153757] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[4]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome VII." Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E. , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K. Nature 387:81-84(1997) [PubMed: 9169869] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[5]	"A family of cyclin-like proteins that interact with the Pho85 cyclin-dependent kinase." Measday V., Moore L., Retnakaran R., Lee J., Donoviel M., Neiman A.M., Andrews B.J. Mol. Cell. Biol. 17:1212-1223(1997) [PubMed: 9032248] [Abstract] Cited for: INTERACTION WITH PHO85.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L11612 mRNA. Translation: AAA16919.1. Z72737 Genomic DNA. Translation: CAA96931.1.
PIR	S37607.
RefSeq	NP_011300.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:1507N.
IntAct	P35190. 4 interactions.
STRING	P35190.
Genome annotation databases
Ensembl	YGL215W; YGL215W; YGL215W; Saccharomyces cerevisiae. [Genome view]
GeneID	852657.
KEGG	sce:YGL215W.
NMPDR	fig|4932.3.peg.2403.
Organism-specific databases
CYGD	YGL215w.
SGD	S000003183. CLG1.
Phylogenomic databases
HOGENOM	P35190.
OMA	AFILANK
OrthoDB	EOG9V70ZR
Gene expression databases
ArrayExpress	P35190.
Genevestigator	P35190.
GermOnline	YGL215W. Saccharomyces cerevisiae.
Family and domain databases
PROSITE	PS00292. CYCLINS. False negative. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	971936.

Entry information

Entry name

CLG1_YEAST

Accession

Primary (citable) accession number: P35190

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1994
Last sequence update:	February 1, 1994
Last modified:	November 24, 2009
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)