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P35135

- UBC4_SOLLC

UniProt

P35135 - UBC4_SOLLC

Protein

Ubiquitin-conjugating enzyme E2-17 kDa

Gene
N/A
Organism
Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins By similarity.PROSITE-ProRule annotation

    Catalytic activityi

    ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.PROSITE-ProRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei85 – 851Glycyl thioester intermediatePROSITE-ProRule annotation

    GO - Molecular functioni

    1. acid-amino acid ligase activity Source: InterPro
    2. ATP binding Source: UniProtKB-KW

    GO - Biological processi

    1. protein ubiquitination Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Ligase

    Keywords - Biological processi

    Ubl conjugation pathway

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    UniPathwayiUPA00143.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ubiquitin-conjugating enzyme E2-17 kDa (EC:6.3.2.19)
    Alternative name(s):
    Ubiquitin carrier protein
    Ubiquitin-protein ligase
    OrganismiSolanum lycopersicum (Tomato) (Lycopersicon esculentum)
    Taxonomic identifieri4081 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanumLycopersicon
    ProteomesiUP000004994: Chromosome 6

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 148148Ubiquitin-conjugating enzyme E2-17 kDaPRO_0000082580Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP35135.
    SMRiP35135. Positions 1-147.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotation

    Phylogenomic databases

    KOiK06689.
    OMAiNTHAREW.

    Family and domain databases

    Gene3Di3.10.110.10. 1 hit.
    InterProiIPR000608. UBQ-conjugat_E2.
    IPR023313. UBQ-conjugating_AS.
    IPR016135. UBQ-conjugating_enzyme/RWD.
    [Graphical view]
    PfamiPF00179. UQ_con. 1 hit.
    [Graphical view]
    SUPFAMiSSF54495. SSF54495. 1 hit.
    PROSITEiPS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
    PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P35135-1 [UniParc]FASTAAdd to Basket

    « Hide

    MASKRILKEL KDLQKDPPTS CSAGPVAEDM FHWQATIMGP TDSPYAGGVF    50
    LVSIHFPPDY PFKPPKVAFR TKVFHPNINS NGSICLDILK EQWSPALTIS 100
    KVLLSICSLL TDPNPDDPLV PEIAHMYKTD RAKYETTARS WTQKYAMG 148
    Length:148
    Mass (Da):16,522
    Last modified:February 1, 1994 - v1
    Checksum:i4247FF721B98059F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L23762 mRNA. Translation: AAA34125.1.
    RefSeqiNP_001234247.1. NM_001247318.1.
    XP_004240429.1. XM_004240381.1.
    XP_004240430.1. XM_004240382.1.
    XP_004240431.1. XM_004240383.1.
    XP_004240432.1. XM_004240384.1.
    UniGeneiLes.19083.

    Genome annotation databases

    EnsemblPlantsiSolyc06g007510.2.1; Solyc06g007510.2.1; Solyc06g007510.2.
    Solyc06g082600.2.1; Solyc06g082600.2.1; Solyc06g082600.2.
    GeneIDi100301932.
    101249087.
    KEGGisly:100301932.
    sly:101249087.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L23762 mRNA. Translation: AAA34125.1 .
    RefSeqi NP_001234247.1. NM_001247318.1.
    XP_004240429.1. XM_004240381.1.
    XP_004240430.1. XM_004240382.1.
    XP_004240431.1. XM_004240383.1.
    XP_004240432.1. XM_004240384.1.
    UniGenei Les.19083.

    3D structure databases

    ProteinModelPortali P35135.
    SMRi P35135. Positions 1-147.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi Solyc06g007510.2.1 ; Solyc06g007510.2.1 ; Solyc06g007510.2 .
    Solyc06g082600.2.1 ; Solyc06g082600.2.1 ; Solyc06g082600.2 .
    GeneIDi 100301932.
    101249087.
    KEGGi sly:100301932.
    sly:101249087.

    Phylogenomic databases

    KOi K06689.
    OMAi NTHAREW.

    Enzyme and pathway databases

    UniPathwayi UPA00143 .

    Family and domain databases

    Gene3Di 3.10.110.10. 1 hit.
    InterProi IPR000608. UBQ-conjugat_E2.
    IPR023313. UBQ-conjugating_AS.
    IPR016135. UBQ-conjugating_enzyme/RWD.
    [Graphical view ]
    Pfami PF00179. UQ_con. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54495. SSF54495. 1 hit.
    PROSITEi PS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
    PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Expression of an ubiquitin carrier protein gene in tomato root cells infected with the nematode Meloidogyne incognita."
      Bird D.M., Wilson M.A.
      Submitted (NOV-1993) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Root.

    Entry informationi

    Entry nameiUBC4_SOLLC
    AccessioniPrimary (citable) accession number: P35135
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1994
    Last sequence update: February 1, 1994
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3