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P35135

- UBC4_SOLLC

UniProt

P35135 - UBC4_SOLLC

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Protein
Ubiquitin-conjugating enzyme E2-17 kDa
Gene
N/A
Organism
Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins By similarity.

Catalytic activityi

ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei85 – 851Glycyl thioester intermediate By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. acid-amino acid ligase activity Source: InterPro

GO - Biological processi

  1. protein ubiquitination Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Ubl conjugation pathway

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00143.

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin-conjugating enzyme E2-17 kDa (EC:6.3.2.19)
Alternative name(s):
Ubiquitin carrier protein
Ubiquitin-protein ligase
OrganismiSolanum lycopersicum (Tomato) (Lycopersicon esculentum)
Taxonomic identifieri4081 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanumLycopersicon
ProteomesiUP000004994: Chromosome 6

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 148148Ubiquitin-conjugating enzyme E2-17 kDa
PRO_0000082580Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP35135.
SMRiP35135. Positions 1-147.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK06689.
OMAiNTHAREW.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamiPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiPS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P35135-1 [UniParc]FASTAAdd to Basket

« Hide

MASKRILKEL KDLQKDPPTS CSAGPVAEDM FHWQATIMGP TDSPYAGGVF    50
LVSIHFPPDY PFKPPKVAFR TKVFHPNINS NGSICLDILK EQWSPALTIS 100
KVLLSICSLL TDPNPDDPLV PEIAHMYKTD RAKYETTARS WTQKYAMG 148
Length:148
Mass (Da):16,522
Last modified:February 1, 1994 - v1
Checksum:i4247FF721B98059F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L23762 mRNA. Translation: AAA34125.1.
RefSeqiNP_001234247.1. NM_001247318.1.
XP_004240429.1. XM_004240381.1.
XP_004240430.1. XM_004240382.1.
XP_004240431.1. XM_004240383.1.
XP_004240432.1. XM_004240384.1.
UniGeneiLes.19083.

Genome annotation databases

EnsemblPlantsiSolyc06g007510.2.1; Solyc06g007510.2.1; Solyc06g007510.2.
Solyc06g082600.2.1; Solyc06g082600.2.1; Solyc06g082600.2.
GeneIDi100301932.
101249087.
KEGGisly:100301932.
sly:101249087.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L23762 mRNA. Translation: AAA34125.1 .
RefSeqi NP_001234247.1. NM_001247318.1.
XP_004240429.1. XM_004240381.1.
XP_004240430.1. XM_004240382.1.
XP_004240431.1. XM_004240383.1.
XP_004240432.1. XM_004240384.1.
UniGenei Les.19083.

3D structure databases

ProteinModelPortali P35135.
SMRi P35135. Positions 1-147.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi Solyc06g007510.2.1 ; Solyc06g007510.2.1 ; Solyc06g007510.2 .
Solyc06g082600.2.1 ; Solyc06g082600.2.1 ; Solyc06g082600.2 .
GeneIDi 100301932.
101249087.
KEGGi sly:100301932.
sly:101249087.

Phylogenomic databases

KOi K06689.
OMAi NTHAREW.

Enzyme and pathway databases

UniPathwayi UPA00143 .

Family and domain databases

Gene3Di 3.10.110.10. 1 hit.
InterProi IPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view ]
Pfami PF00179. UQ_con. 1 hit.
[Graphical view ]
SUPFAMi SSF54495. SSF54495. 1 hit.
PROSITEi PS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Expression of an ubiquitin carrier protein gene in tomato root cells infected with the nematode Meloidogyne incognita."
    Bird D.M., Wilson M.A.
    Submitted (NOV-1993) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Root.

Entry informationi

Entry nameiUBC4_SOLLC
AccessioniPrimary (citable) accession number: P35135
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: September 3, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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