##gff-version 3
P35123	UniProtKB	Chain	1	962	.	.	.	ID=PRO_0000080622;Note=Ubiquitin carboxyl-terminal hydrolase 4	
P35123	UniProtKB	Domain	11	122	.	.	.	Note=DUSP;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00613	
P35123	UniProtKB	Domain	142	226	.	.	.	Note=Ubiquitin-like 1;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P35123	UniProtKB	Domain	302	922	.	.	.	Note=USP;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01035	
P35123	UniProtKB	Domain	483	571	.	.	.	Note=Ubiquitin-like 2;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P35123	UniProtKB	Region	27	216	.	.	.	Note=Necessary for interaction with SART3;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q13107	
P35123	UniProtKB	Region	220	249	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P35123	UniProtKB	Region	229	295	.	.	.	Note=Required for USP4 activation by providing conformational flexibility between the DUSP and catalytic domains;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q13107	
P35123	UniProtKB	Region	384	386	.	.	.	Note=Regulates ubiquitin dissociation;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q13107	
P35123	UniProtKB	Region	405	407	.	.	.	Note=Necessary for interaction with RBL2;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11571651;Dbxref=PMID:11571651	
P35123	UniProtKB	Region	459	463	.	.	.	Note=Necessary for interaction with RB1 and RBL2;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11571651;Dbxref=PMID:11571651	
P35123	UniProtKB	Region	485	774	.	.	.	Note=Interacts with DUSP and ubiquitin-like 1 domains and is required for USP4 activation;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q13107	
P35123	UniProtKB	Region	638	699	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P35123	UniProtKB	Region	928	962	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P35123	UniProtKB	Motif	133	141	.	.	.	Note=Nuclear export signal;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15494318;Dbxref=PMID:15494318	
P35123	UniProtKB	Motif	766	771	.	.	.	Note=Nuclear localization signal;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15494318;Dbxref=PMID:15494318	
P35123	UniProtKB	Compositional bias	221	249	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P35123	UniProtKB	Compositional bias	928	945	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P35123	UniProtKB	Active site	311	311	.	.	.	Note=Nucleophile;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01035	
P35123	UniProtKB	Active site	880	880	.	.	.	Note=Proton acceptor;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01035	
P35123	UniProtKB	Binding site	461	461	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q13107	
P35123	UniProtKB	Binding site	464	464	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q13107	
P35123	UniProtKB	Binding site	798	798	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q13107	
P35123	UniProtKB	Binding site	801	801	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q13107	
P35123	UniProtKB	Modified residue	445	445	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q13107	
P35123	UniProtKB	Modified residue	655	655	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:B2GUZ1	
P35123	UniProtKB	Modified residue	675	675	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079	
P35123	UniProtKB	Modified residue	680	680	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079	
P35123	UniProtKB	Mutagenesis	461	461	.	.	.	Note=Reduces the interaction with RB1. C->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11571651;Dbxref=PMID:11571651	
P35123	UniProtKB	Mutagenesis	770	771	.	.	.	Note=Reduces nuclear localization. KK->NS;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15494318;Dbxref=PMID:15494318	
P35123	UniProtKB	Sequence conflict	123	124	.	.	.	Note=EH->DD;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P35123	UniProtKB	Sequence conflict	292	292	.	.	.	Note=P->A;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P35123	UniProtKB	Helix	13	21	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Turn	22	25	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Beta strand	33	38	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Helix	39	49	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Beta strand	51	53	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Turn	56	60	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Helix	62	64	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Helix	72	74	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Beta strand	75	77	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Turn	78	81	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Turn	89	91	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Beta strand	92	97	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Helix	98	108	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Beta strand	118	124	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Beta strand	126	128	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Beta strand	130	133	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Beta strand	138	144	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Beta strand	147	156	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Helix	162	172	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Beta strand	181	185	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Beta strand	187	191	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Turn	202	206	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU	
P35123	UniProtKB	Beta strand	211	217	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3JYU