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P35051

- TRYP_PROAT

UniProt

P35051 - TRYP_PROAT

Protein

Trypsin

Gene
N/A
Organism
Protopterus aethiopicus (Marbled lungfish)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Catalytic activityi

    Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

    GO - Molecular functioni

    1. serine-type peptidase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protease, Serine protease

    Protein family/group databases

    MEROPSiS01.125.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Trypsin (EC:3.4.21.4)
    OrganismiProtopterus aethiopicus (Marbled lungfish)
    Taxonomic identifieri7886 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiDipnoiLepidosireniformesProtopteridaeProtopterus

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular space Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Propeptidei1 – 77Activation peptidePRO_0000028313
    Chaini8 – ›21›14TrypsinPRO_0000028314Add
    BLAST

    Keywords - PTMi

    Zymogen

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini8 – ›21›14Peptidase S1PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the peptidase S1 family.PROSITE-ProRule annotation
    Contains 1 peptidase S1 domain.PROSITE-ProRule annotation

    Sequencei

    Sequence statusi: Fragment.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P35051-1 [UniParc]FASTAAdd to Basket

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    FPIEEDKIVG GYECPKHXVP W                                  21
    Length:21
    Mass (Da):2,455
    Last modified:February 1, 1994 - v1
    Checksum:i88E2FB11D130729D
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei21 – 211

    Sequence databases

    PIRiA27719.

    Cross-referencesi

    Sequence databases

    PIRi A27719.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    MEROPSi S01.125.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Comparison of the amino terminal sequences of bovine, dogfish, and lungfish trypsinogens."
      Hermodson M.A., Tye R.W., Reeck G.R., Neurath H., Walsh K.A.
      FEBS Lett. 14:222-224(1971) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE.
      Tissue: Pancreas.

    Entry informationi

    Entry nameiTRYP_PROAT
    AccessioniPrimary (citable) accession number: P35051
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1994
    Last sequence update: February 1, 1994
    Last modified: October 1, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. Peptidase families
      Classification of peptidase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3