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P35051 (TRYP_PROAT) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length21 AA.
Sequence statusFragment.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

Subcellular location

Secretedextracellular space.

Sequence similarities

Belongs to the peptidase S1 family.

Contains 1 peptidase S1 domain.

Ontologies

Keywords
   Cellular componentSecreted
   Molecular functionHydrolase
Protease
Serine protease
   PTMZymogen
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Cellular_componentextracellular space

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionserine-type peptidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Propeptide1 – 77Activation peptide
PRO_0000028313
Chain8 – ›21›14Trypsin
PRO_0000028314

Regions

Domain8 – ›21›14Peptidase S1

Experimental info

Non-terminal residue211

Sequences

Sequence LengthMass (Da)Tools
P35051 [UniParc].

Last modified February 1, 1994. Version 1.
Checksum: 88E2FB11D130729D

FASTA212,455
        10         20 
FPIEEDKIVG GYECPKHXVP W 

« Hide

References

[1]"Comparison of the amino terminal sequences of bovine, dogfish, and lungfish trypsinogens."
Hermodson M.A., Tye R.W., Reeck G.R., Neurath H., Walsh K.A.
FEBS Lett. 14:222-224(1971) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE.
Tissue: Pancreas.

Cross-references

Sequence databases

PIRA27719.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein family/group databases

MEROPSS01.125.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameTRYP_PROAT
AccessionPrimary (citable) accession number: P35051
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: May 14, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries