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Protein

Trypsin

Gene
N/A
Organism
Penaeus monodon (Giant tiger prawn)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

High efficiency toward native protein substrates including collagens.

Catalytic activityi

Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Serine protease

Protein family/group databases

MEROPSiS01.111.

Names & Taxonomyi

Protein namesi
Recommended name:
Trypsin (EC:3.4.21.4)
OrganismiPenaeus monodon (Giant tiger prawn)
Taxonomic identifieri6687 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMalacostracaEumalacostracaEucaridaDecapodaDendrobranchiataPenaeoideaPenaeidaePenaeus

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000887191 – ›32TrypsinAdd BLAST›32

Structurei

3D structure databases

ProteinModelPortaliP35050.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – ›32Peptidase S1PROSITE-ProRule annotationAdd BLAST›32

Sequence similaritiesi

Belongs to the peptidase S1 family.PROSITE-ProRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR009003. Peptidase_S1_PA.
SUPFAMiSSF50494. SSF50494. 1 hit.

Sequencei

Sequence statusi: Fragment.

P35050-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30 
IVGGTAVTPG EFPYQLSFQD SIEGVESHFC GG
Length:32
Mass (Da):3,330
Last modified:February 1, 1994 - v1
Checksum:i96A3A5D1F4B19182
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei321

Sequence databases

PIRiS11537.

Cross-referencesi

Sequence databases

PIRiS11537.

3D structure databases

ProteinModelPortaliP35050.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiS01.111.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiView protein in InterPro
IPR009003. Peptidase_S1_PA.
SUPFAMiSSF50494. SSF50494. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTRYP_PENMO
AccessioniPrimary (citable) accession number: P35050
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: February 15, 2017
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.