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Protein

Trypsin

Gene
N/A
Organism
Penaeus monodon (Giant tiger prawn)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

High efficiency toward native protein substrates including collagens.

Catalytic activityi

Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Serine protease

Protein family/group databases

MEROPSiS01.111.

Names & Taxonomyi

Protein namesi
Recommended name:
Trypsin (EC:3.4.21.4)
OrganismiPenaeus monodon (Giant tiger prawn)
Taxonomic identifieri6687 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMalacostracaEumalacostracaEucaridaDecapodaDendrobranchiataPenaeoideaPenaeidaePenaeus

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – ›32›32TrypsinPRO_0000088719Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP35050.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – ›32›32Peptidase S1PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the peptidase S1 family.PROSITE-ProRule annotation
Contains 1 peptidase S1 domain.PROSITE-ProRule annotation

Family and domain databases

InterProiIPR009003. Peptidase_S1_PA.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.

Sequencei

Sequence statusi: Fragment.

P35050-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30 
IVGGTAVTPG EFPYQLSFQD SIEGVESHFC GG
Length:32
Mass (Da):3,330
Last modified:February 1, 1994 - v1
Checksum:i96A3A5D1F4B19182
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei32 – 321

Sequence databases

PIRiS11537.

Cross-referencesi

Sequence databases

PIRiS11537.

3D structure databases

ProteinModelPortaliP35050.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiS01.111.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR009003. Peptidase_S1_PA.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTRYP_PENMO
AccessioniPrimary (citable) accession number: P35050
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: September 16, 2015
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.