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P35050 (TRYP_PENMO) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Trypsin

EC=3.4.21.4
OrganismPenaeus monodon (Giant tiger prawn)
Taxonomic identifier6687 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMalacostracaEumalacostracaEucaridaDecapodaDendrobranchiataPenaeoideaPenaeidaePenaeus

Protein attributes

Sequence length32 AA.
Sequence statusFragment.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

High efficiency toward native protein substrates including collagens.

Catalytic activity

Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

Subcellular location

Secretedextracellular space.

Sequence similarities

Belongs to the peptidase S1 family.

Contains 1 peptidase S1 domain.

Ontologies

Keywords
   Cellular componentSecreted
   Molecular functionHydrolase
Protease
Serine protease
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Biological_processproteolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentextracellular space

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionserine-type peptidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – ›32›32Trypsin
PRO_0000088719

Regions

Domain1 – ›32›32Peptidase S1

Experimental info

Non-terminal residue321

Sequences

Sequence LengthMass (Da)Tools
P35050 [UniParc].

Last modified February 1, 1994. Version 1.
Checksum: 96A3A5D1F4B19182

FASTA323,330
        10         20         30 
IVGGTAVTPG EFPYQLSFQD SIEGVESHFC GG 

« Hide

References

[1]"The midgut trypsins of shrimp (Penaeus monodon). High efficiency toward native protein substrates including collagens."
Lu P.J., Liu H.C., Tsai I.H.
Biol. Chem. Hoppe-Seyler 371:851-859(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE.
Tissue: Midgut.

Cross-references

Sequence databases

PIRS11537.

3D structure databases

ProteinModelPortalP35050.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

MEROPSS01.111.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR009003. Trypsin-like_Pept_dom.
[Graphical view]
SUPFAMSSF50494. SSF50494. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRYP_PENMO
AccessionPrimary (citable) accession number: P35050
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: February 19, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries