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Protein

Trypsin

Gene
N/A
Organism
Penaeus monodon (Giant tiger prawn)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

High efficiency toward native protein substrates including collagens.

Catalytic activityi

Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Serine protease

Protein family/group databases

MEROPSiS01.111.

Names & Taxonomyi

Protein namesi
Recommended name:
Trypsin (EC:3.4.21.4)
OrganismiPenaeus monodon (Giant tiger prawn)
Taxonomic identifieri6687 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMalacostracaEumalacostracaEucaridaDecapodaDendrobranchiataPenaeoideaPenaeidaePenaeus

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000887191 – ›32TrypsinAdd BLAST›32

Structurei

3D structure databases

ProteinModelPortaliP35050.
SMRiP35050.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – ›32Peptidase S1PROSITE-ProRule annotationAdd BLAST›32

Sequence similaritiesi

Belongs to the peptidase S1 family.PROSITE-ProRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR009003. Peptidase_S1_PA.
SUPFAMiSSF50494. SSF50494. 1 hit.

Sequencei

Sequence statusi: Fragment.

P35050-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30 
IVGGTAVTPG EFPYQLSFQD SIEGVESHFC GG
Length:32
Mass (Da):3,330
Last modified:February 1, 1994 - v1
Checksum:i96A3A5D1F4B19182
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei321

Sequence databases

PIRiS11537.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiTRYP_PENMO
AccessioniPrimary (citable) accession number: P35050
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: May 10, 2017
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families