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P35043 (TRYA3_LUCCU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein attributes

Sequence length165 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

Subcellular location

Secretedextracellular space.

Sequence similarities

Belongs to the peptidase S1 family.

Contains 1 peptidase S1 domain.

Ontologies

Keywords
   Cellular componentSecreted
   Molecular functionHydrolase
Protease
Serine protease
   PTMDisulfide bond
Gene Ontology (GO)
   Biological_processproteolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentextracellular space

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionserine-type endopeptidase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – 165›165Trypsin alpha-3
PRO_0000088717

Regions

Domain‹1 – 163›163Peptidase S1

Sites

Active site261Charge relay system By similarity
Active site1191Charge relay system By similarity
Site1131Required for specificity By similarity

Amino acid modifications

Disulfide bond89 ↔ 106 By similarity
Disulfide bond115 ↔ 139 By similarity

Experimental info

Non-terminal residue11

Sequences

Sequence LengthMass (Da)Tools
P35043 [UniParc].

Last modified February 1, 1994. Version 1.
Checksum: 26160B1AFF80F1CD

FASTA16516,570
        10         20         30         40         50         60 
NSGGVLVSVA AFKNHEGYNS KTMVNDIAVI RLSSSLTTSS TIKTIGLATA APANGAAATV 

        70         80         90        100        110        120 
SGWGTTSSGG SIPSQLRYVD VKIVGRTQCA SSTYGYGSEI KASMICAYTV GKDSCQGDSG 

       130        140        150        160 
GPLVSGGRLV GVVSWGYGCA AVNYPGVYAD VAALRSWVVS AANSV 

« Hide

References

[1]"Isolation of a trypsin-like serine protease gene family from the sheep blowfly Lucilia cuprina."
Casu R.E., Jarmey J.M., Elvin C.M., Eisemann C.H.
Insect Mol. Biol. 3:159-170(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L15632 Genomic DNA. Translation: AAA65931.1.

3D structure databases

ProteinModelPortalP35043.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

MEROPSS01.112.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR001254. Peptidase_S1.
IPR018114. Peptidase_S1_AS.
IPR001314. Peptidase_S1A.
IPR009003. Trypsin-like_Pept_dom.
[Graphical view]
PfamPF00089. Trypsin. 1 hit.
[Graphical view]
PRINTSPR00722. CHYMOTRYPSIN.
SMARTSM00020. Tryp_SPc. 1 hit.
[Graphical view]
SUPFAMSSF50494. SSF50494. 1 hit.
PROSITEPS50240. TRYPSIN_DOM. 1 hit.
PS00135. TRYPSIN_SER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTRYA3_LUCCU
AccessionPrimary (citable) accession number: P35043
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: February 19, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries