P35002 (CTRP_PENMO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Chymotrypsin EC=3.4.21.1
Organism	Penaeus monodon (Giant tiger prawn)
Taxonomic identifier	6687 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Arthropoda › Crustacea › Malacostraca › Eumalacostraca › Eucarida › Decapoda › Dendrobranchiata › Penaeoidea › Penaeidae › Penaeus

Protein attributes

Sequence length	31 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	Preferential cleavage: Tyr-|-Xaa, Trp-|-Xaa, Phe-|-Xaa, Leu-|-Xaa.
Subcellular location	Secreted › extracellular space.
Sequence similarities	Belongs to the peptidase S1 family. Contains 1 peptidase S1 domain.

Ontologies

Keywords
Cellular component	Secreted
Molecular function	Hydrolase Protease Serine protease
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular space Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	serine-type endopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›31	›31	Chymotrypsin		PRO_0000088675
Regions
	Domain	1 – ›31	›31	Peptidase S1
Experimental info
	Non-terminal residue	31	1

Sequences

	Sequence		Length	Mass (Da)
	P35002 [UniParc]. Last modified February 1, 1994. Version 1. Checksum: 6CCD1D09067D1D78	FASTA	31	3,287
	10 20 30 IVGGVEAVPG VWPYQAALFI IDMYFCGGSL I

References

[1]	"The midgut chymotrypsins of shrimps (Penaeus monodon, Penaeus japonicus and Penaeus penicillatus)." Tsai I.H., Lu P.J., Chuang J.L. Biochim. Biophys. Acta 1080:59-67(1991) [PubMed: 1657178] [Abstract] Cited for: PROTEIN SEQUENCE. Tissue: Midgut.
+	Additional computationally mapped references.

Cross-references

Sequence databases
PIR	S18356.
3D structure databases
ProteinModelPortal	P35002.
SMR	P35002. Positions 1-31.
ModBase	Search...
Protein family/group databases
MEROPS	S01.122.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR009003. Pept_cys/ser_Trypsin-like. IPR001254. Peptidase_S1_S6. [Graphical view]
Pfam	PF00089. Trypsin. 1 hit. [Graphical view]
SUPFAM	SSF50494. Pept_Ser_Cys. 1 hit.
PROSITE	PS50240. TRYPSIN_DOM. Partial match. PS00134. TRYPSIN_HIS. Partial match. PS00135. TRYPSIN_SER. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CTRP_PENMO

Accession

Primary (citable) accession number: P35002

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1994
Last sequence update:	February 1, 1994
Last modified:	November 16, 2011
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)