Quinol oxidase subunit 2 precursor - Bacillus subtilis (strain 168)

Contribute

Send feedback

Read comments (?) or add your own

P34957 (QOX2_BACSU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 115. History...

Clusters with 100%, 90%, 50% identity |

Documents (2) |

Third-party data

text xml rdf/xml gff fasta

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Quinol oxidase subunit 2
EC=1.10.3.-

Alternative name(s):
Oxidase aa(3)-600 subunit 2
Quinol oxidase aa3-600, subunit QoxA
Quinol oxidase polypeptide II

Gene names

Name:	qoxA
Ordered Locus Names:	BSU38170
ORF Names:	ipa-37d

Organism

Bacillus subtilis (strain 168) [Reference proteome] [HAMAP]

Taxonomic identifier

224308 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus ›

Protein attributes

Sequence length	321 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I By similarity.
Catalytic activity	Ubiquinol-8 + O₂ = Ubiquinone-8 + H₂O.
Subcellular location	Cell membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the cytochrome c oxidase subunit 2 family.
Sequence caution	The sequence AAA22686.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Ontologies

Keywords
Biological process	Electron transport Respiratory chain Transport
Cellular component	Cell membrane Membrane
Domain	Signal Transmembrane Transmembrane helix
Molecular function	Oxidoreductase
PTM	Lipoprotein Palmitate
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	ATP synthesis coupled electron transport Inferred from sequence or structural similarity. Source: UniProtKB mitochondrial electron transport, ubiquinol to cytochrome c Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell respiratory chain Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	copper ion binding Inferred from electronic annotation. Source: InterPro cytochrome bo3 ubiquinol oxidase activity Inferred from electronic annotation. Source: InterPro cytochrome o ubiquinol oxidase activity Inferred from electronic annotation. Source: InterPro cytochrome-c oxidase activity Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor Inferred from sequence or structural similarity. Source: UniProtKB
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Signal peptide

1 – 25

By similarity

Chain

26 – 321

296

Quinol oxidase subunit 2

PRO_0000006069

Regions

Transmembrane

49 – 69

Helical; Potential

Transmembrane

90 – 110

Helical; Potential

Amino acid modifications

Lipidation

N-palmitoyl cysteine Potential

Lipidation

S-diacylglycerol cysteine Potential

Experimental info

Sequence conflict

V → VD in AAA22686. Ref.1

Sequence conflict

V → VD in CAA51593. Ref.2

Sequence conflict

167

F → C in AAA22686. Ref.1

Sequence conflict

167

F → C in CAA51593. Ref.2

Sequence conflict

300

S → C in AAA22686. Ref.1

Sequence conflict

300

S → C in CAA51593. Ref.2

Sequences

Sequence

Length

Mass (Da)

Tools

P34957 [UniParc].

Last modified June 16, 2009. Version 4.
Checksum: 6E4573332345DE7D
Show »

FASTA

321

36,282

        10         20         30         40         50         60 
MIFLFRALKP LLVLALLTVV FVLGGCSNAS VLDPKGPVAE QQSDLILLSI GFMLFIVGVV 

        70         80         90        100        110        120 
FVLFTIILVK YRDRKGKDNG SYNPEIHGNT FLEVVWTVIP ILIVIALSVP TVQTIYSLEK 

       130        140        150        160        170        180 
APEATKDKEP LVVYATSVDW KWVFSYPEQD IETVNYLNIP VDRPILFKIS SADSMASLWI 

       190        200        210        220        230        240 
PQLGGQKYAM AGMLMDQYLQ ADKVGTYEGR NANFTGEHFA DQEFDVNAVT EKDFNSWVKK 

       250        260        270        280        290        300 
TQNEAPKLTK EKYDELMLPE NVDELTFSST HLKYVDHGQD AEYAMEARKR LGYQAVSPHS 

       310        320 
KTDPFENVKK NEFKKSDDTE E

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Molecular cloning, sequencing, and physiological characterization of the qox operon from Bacillus subtilis encoding the aa3-600 quinol oxidase." Santana M., Kunst F., Hullo M.-F., Rapoport G., Danchin A., Glaser P. J. Biol. Chem. 267:10225-10231(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168.
[2]	"Bacillus subtilis genome project: cloning and sequencing of the 97 kb region from 325 degrees to 333 degrees." Glaser P., Kunst F., Arnaud M., Coudart M.P., Gonzales W., Hullo M.-F., Ionescu M., Lubochinsky B., Marcelino L., Moszer I., Presecan E., Santana M., Schneider E., Schweizer J., Vertes A., Rapoport G., Danchin A. Mol. Microbiol. 10:371-384(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168.
[3]	"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. Danchin A. Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168.
[4]	"From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later." Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A., Vallenet D., Wang T., Moszer I., Medigue C., Danchin A. Microbiology 155:1758-1775(2009) [PubMed] [Europe PMC] [Abstract] Cited for: SEQUENCE REVISION TO 38; 167 AND 300.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M86548 Genomic DNA. Translation: AAA22686.1. Different initiation. X73124 Genomic DNA. Translation: CAA51593.1. AL009126 Genomic DNA. Translation: CAB15843.2.
PIR	E69687.
RefSeq	NP_391696.2. NC_000964.3.
3D structure databases
ProteinModelPortal	P34957.
SMR	P34957. Positions 30-271.
ModBase	Search...
Protein-protein interaction databases
STRING	224308.BSU38170.
Proteomic databases
PaxDb	P34957.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAB15843; CAB15843; BSU38170.
GeneID	937295.
KEGG	bsu:BSU38170.
PATRIC	18979678. VBIBacSub10457_4001.
Organism-specific databases
GenoList	BSU38170. [Micado]
Phylogenomic databases
eggNOG	COG1622.
HOGENOM	HOG000084157.
KO	K02826.
ProtClustDB	CLSK873209.
Enzyme and pathway databases
BioCyc	BSUB:BSU38170-MONOMER. MetaCyc:BSU38170-MONOMER.
Family and domain databases
Gene3D	1.10.287.90. 1 hit. 2.60.40.420. 1 hit.
InterPro	IPR012141. Bo-type_Ubol_Oxase_su_II. IPR010514. COX_ARM. IPR008972. Cupredoxin. IPR006332. Cyt_aa3_quinol_oxidase_su2. IPR002429. Cyt_c_oxidase_su2_C. IPR011759. Cyt_c_oxidase_su2_TM_dom. [Graphical view]
Pfam	PF02790. COX2_TM. 1 hit. PF06481. COX_ARM. 1 hit. [Graphical view]
PIRSF	PIRSF000292. Ubi_od_II. 1 hit.
SUPFAM	SSF49503. Cupredoxin. 1 hit. SSF81464. Cyt_c_oxidase_II-like_TM. 1 hit.
TIGRFAMs	TIGR01432. QOXA. 1 hit.
PROSITE	PS50857. COX2_CUA. 1 hit. PS50999. COX2_TM. 1 hit. PS51257. PROKAR_LIPOPROTEIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

QOX2_BACSU

Accession

Primary (citable) accession number: P34957
Secondary accession number(s): O32281

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1994
Last sequence update:	June 16, 2009
Last modified:	May 1, 2013
This is version 115 of the entry and version 4 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

Bacillus subtilis

Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Amino acid modifications

Experimental info

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry information

Relevant documents