Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Quinol oxidase subunit 2

Gene

qoxA

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I (By similarity).By similarity

Catalytic activityi

Ubiquinol-8 + O2 = Ubiquinone-8 + H2O.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Enzyme and pathway databases

BioCyciBSUB:BSU38170-MONOMER.
MetaCyc:BSU38170-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Quinol oxidase subunit 2 (EC:1.10.3.-)
Alternative name(s):
Oxidase aa(3)-600 subunit 2
Quinol oxidase aa3-600, subunit QoxA
Quinol oxidase polypeptide II
Gene namesi
Name:qoxA
Ordered Locus Names:BSU38170
ORF Names:ipa-37d
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei49 – 69HelicalSequence analysisAdd BLAST21
Transmembranei90 – 110HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25PROSITE-ProRule annotationAdd BLAST25
ChainiPRO_000000606926 – 321Quinol oxidase subunit 2Add BLAST296

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi26N-palmitoyl cysteinePROSITE-ProRule annotation1
Lipidationi26S-diacylglycerol cysteinePROSITE-ProRule annotation1

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiP34957.
PRIDEiP34957.

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100020606.

Structurei

3D structure databases

ProteinModelPortaliP34957.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105E2S. Bacteria.
COG1622. LUCA.
HOGENOMiHOG000084157.
InParanoidiP34957.
KOiK02826.
OMAiTAMNSFF.
PhylomeDBiP34957.

Family and domain databases

Gene3Di1.10.287.90. 1 hit.
2.60.40.420. 1 hit.
InterProiIPR008972. Cupredoxin.
IPR002429. Cyt_c_oxidase_su2_C.
IPR011759. Cyt_c_oxidase_su2_TM_dom.
IPR006333. Cyt_o_ubiquinol_oxidase_su2.
IPR006332. QoxA.
[Graphical view]
PfamiPF00116. COX2. 1 hit.
PF02790. COX2_TM. 1 hit.
[Graphical view]
PIRSFiPIRSF000292. Ubi_od_II. 1 hit.
SUPFAMiSSF49503. SSF49503. 1 hit.
SSF81464. SSF81464. 1 hit.
TIGRFAMsiTIGR01432. QOXA. 1 hit.
PROSITEiPS50857. COX2_CUA. 1 hit.
PS50999. COX2_TM. 1 hit.
PS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P34957-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIFLFRALKP LLVLALLTVV FVLGGCSNAS VLDPKGPVAE QQSDLILLSI
60 70 80 90 100
GFMLFIVGVV FVLFTIILVK YRDRKGKDNG SYNPEIHGNT FLEVVWTVIP
110 120 130 140 150
ILIVIALSVP TVQTIYSLEK APEATKDKEP LVVYATSVDW KWVFSYPEQD
160 170 180 190 200
IETVNYLNIP VDRPILFKIS SADSMASLWI PQLGGQKYAM AGMLMDQYLQ
210 220 230 240 250
ADKVGTYEGR NANFTGEHFA DQEFDVNAVT EKDFNSWVKK TQNEAPKLTK
260 270 280 290 300
EKYDELMLPE NVDELTFSST HLKYVDHGQD AEYAMEARKR LGYQAVSPHS
310 320
KTDPFENVKK NEFKKSDDTE E
Length:321
Mass (Da):36,282
Last modified:June 16, 2009 - v4
Checksum:i6E4573332345DE7D
GO

Sequence cautioni

The sequence AAA22686 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti38V → VD in AAA22686 (PubMed:1316894).Curated1
Sequence conflicti38V → VD in CAA51593 (PubMed:7934828).Curated1
Sequence conflicti167F → C in AAA22686 (PubMed:1316894).Curated1
Sequence conflicti167F → C in CAA51593 (PubMed:7934828).Curated1
Sequence conflicti300S → C in AAA22686 (PubMed:1316894).Curated1
Sequence conflicti300S → C in CAA51593 (PubMed:7934828).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M86548 Genomic DNA. Translation: AAA22686.1. Different initiation.
X73124 Genomic DNA. Translation: CAA51593.1.
AL009126 Genomic DNA. Translation: CAB15843.2.
PIRiE69687.
RefSeqiNP_391696.2. NC_000964.3.
WP_010886637.1. NC_000964.3.

Genome annotation databases

EnsemblBacteriaiCAB15843; CAB15843; BSU38170.
GeneIDi937295.
KEGGibsu:BSU38170.
PATRICi18979678. VBIBacSub10457_4001.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M86548 Genomic DNA. Translation: AAA22686.1. Different initiation.
X73124 Genomic DNA. Translation: CAA51593.1.
AL009126 Genomic DNA. Translation: CAB15843.2.
PIRiE69687.
RefSeqiNP_391696.2. NC_000964.3.
WP_010886637.1. NC_000964.3.

3D structure databases

ProteinModelPortaliP34957.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100020606.

Proteomic databases

PaxDbiP34957.
PRIDEiP34957.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB15843; CAB15843; BSU38170.
GeneIDi937295.
KEGGibsu:BSU38170.
PATRICi18979678. VBIBacSub10457_4001.

Phylogenomic databases

eggNOGiENOG4105E2S. Bacteria.
COG1622. LUCA.
HOGENOMiHOG000084157.
InParanoidiP34957.
KOiK02826.
OMAiTAMNSFF.
PhylomeDBiP34957.

Enzyme and pathway databases

BioCyciBSUB:BSU38170-MONOMER.
MetaCyc:BSU38170-MONOMER.

Family and domain databases

Gene3Di1.10.287.90. 1 hit.
2.60.40.420. 1 hit.
InterProiIPR008972. Cupredoxin.
IPR002429. Cyt_c_oxidase_su2_C.
IPR011759. Cyt_c_oxidase_su2_TM_dom.
IPR006333. Cyt_o_ubiquinol_oxidase_su2.
IPR006332. QoxA.
[Graphical view]
PfamiPF00116. COX2. 1 hit.
PF02790. COX2_TM. 1 hit.
[Graphical view]
PIRSFiPIRSF000292. Ubi_od_II. 1 hit.
SUPFAMiSSF49503. SSF49503. 1 hit.
SSF81464. SSF81464. 1 hit.
TIGRFAMsiTIGR01432. QOXA. 1 hit.
PROSITEiPS50857. COX2_CUA. 1 hit.
PS50999. COX2_TM. 1 hit.
PS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQOX2_BACSU
AccessioniPrimary (citable) accession number: P34957
Secondary accession number(s): O32281
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: June 16, 2009
Last modified: November 30, 2016
This is version 138 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.