Reviewed, UniProtKB/Swiss-Prot P34944 (NDUS3_MARPO)

Names and origin

Protein names

Recommended name:
    NADH-ubiquinone oxidoreductase 27 kDa subunit
    EC=1.6.5.3
    EC=1.6.99.3
Alternative name(s):
    Complex I-27kD
      Short name=CI-27kD
    NADH dehydrogenase subunit 9

Gene names

Name:

NAD9

Encoded on

Mitochondrion

Organism

Marchantia polymorpha (Liverwort)

Taxonomic identifier

3197 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Marchantiophyta › Superclass II › Marchantiopsida › Marchantiidae › Marchantiales › Marchantiaceae › Marchantia

Protein attributes

Sequence length	195 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity.
Catalytic activity	NADH + ubiquinone = NAD+ + ubiquinol. NADH + acceptor = NAD+ + reduced acceptor.
Subunit structure	Complex I is composed of about 30 different subunits.
Subcellular location	Mitochondrion inner membrane.
Sequence similarities	Belongs to the complex I 30 kDa subunit family.

Ontologies

Keywords
Biological process	Electron transport Respiratory chain Transport
Cellular component	Membrane Mitochondrion Mitochondrion inner membrane
Ligand	NAD Ubiquinone
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	mitochondrial inner membrane Inferred from electronic annotation. Source: UniProtKB-SubCell respiratory chain Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	NADH dehydrogenase (ubiquinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 195	195	NADH-ubiquinone oxidoreductase 27 kDa subunit		PRO_0000118641

Sequences

	Sequence		Length	Mass (Da)
	P34944-1 [UniParc]. Last modified November 1, 1997. Version 2. Checksum: D123890812812ABB	FASTA	195	23,354
	10 20 30 40 50 60 MDNQLFFKSL IATLPKWIHK CQTSKHENIL YTNPNSLFQL LYFLKYHTNT RFKVLIDICG 70 80 90 100 110 120 VDYPSRKRRF EVVYNLLSID YNTRIRILTS VDEITPICSV VSIFPSAGWW ERETWDMFGV 130 140 150 160 170 180 YFSNHPDLRR ILTDYGFEGH PLRKDFPLSG YVEVRYDDSE KRVVSEPIEM TQEFRYFDFA 190 SPWEQMSRSD ESNQK

References

[1]

"Gene organization deduced from the complete sequence of liverwort Marchantia polymorpha mitochondrial DNA. A primitive form of plant mitochondrial genome." Oda K., Yamato K., Ohta E., Nakamura Y., Takemura M., Nozato N., Akashi K., Kanegae T., Ogura Y., Kohchi T., Ohyama K. J. Mol. Biol. 223:1-7(1992) [PubMed: 1731062] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	M68929 Genomic DNA. Translation: AAC09443.1. Different initiation.
PIR	S25996.
RefSeq	NP_054446.1.
3D structure databases
SMR	P34944. Positions 31-188.
ModBase	Search...
Genome annotation databases
GeneID	2948426.
Enzyme and pathway databases
BRENDA	1.6.5.3. 96730. 1.6.99.3. 96730.
Family and domain databases
InterPro	IPR010218. NADH_DH_csu. IPR001268. NADH_UbQ_OxRdtase_30kDa_su. IPR020396. NADH_UbQ_OxRdtase_CS. [Graphical view]
Pfam	PF00329. Complex1_30kDa. 1 hit. [Graphical view]
ProDom	PD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR01961. NuoC_fam. 1 hit.
PROSITE	PS00542. COMPLEX1_30K. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NDUS3_MARPO

Accession

Primary (citable) accession number: P34944

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1994
Last sequence update:	November 1, 1997
Last modified:	February 9, 2010
This is version 66 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)