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P34883

- MTAB_SYNP2

UniProt

P34883 - MTAB_SYNP2

Protein

Modification methylase AquI subunit beta

Gene

aquIMB

Organism
Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 1 (01 Feb 1994)
      Previous versions | rss
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    Functioni

    This methylase recognizes the double-stranded sequence CYCGRG, causes specific methylation on C-1 on both strands, and protects the DNA from cleavage by the AquI endonuclease.

    Catalytic activityi

    S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.

    GO - Molecular functioni

    1. DNA (cytosine-5-)-methyltransferase activity Source: UniProtKB-EC
    2. DNA binding Source: InterPro

    GO - Biological processi

    1. DNA restriction-modification system Source: UniProtKB-KW

    Keywords - Molecular functioni

    Methyltransferase, Transferase

    Keywords - Biological processi

    Restriction system

    Keywords - Ligandi

    S-adenosyl-L-methionine

    Enzyme and pathway databases

    BioCyciSSP32049:GKF7-1189-MONOMER.

    Protein family/group databases

    REBASEi3283. M.AquI.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Modification methylase AquI subunit beta (EC:2.1.1.37)
    Short name:
    M.AquI subunit beta
    Short name:
    M.AquIB
    Alternative name(s):
    Cytosine-specific methyltransferase AquI subunit beta
    Gene namesi
    Name:aquIMB
    Ordered Locus Names:SYNPCC7002_A1188.1
    OrganismiSynechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum)
    Taxonomic identifieri32049 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus
    ProteomesiUP000001688: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 139139Modification methylase AquI subunit betaPRO_0000087855Add
    BLAST

    Interactioni

    Subunit structurei

    Heterodimer of an alpha and a beta subunit.

    Structurei

    3D structure databases

    ProteinModelPortaliP34883.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini1 – 135135SAM-dependent MTase C5-typePROSITE-ProRule annotationAdd
    BLAST

    Domaini

    Corresponds to the C-terminal half of the enzymatic domain.

    Sequence similaritiesi

    Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.PROSITE-ProRule annotation
    Contains 1 SAM-dependent MTase C5-type domain.PROSITE-ProRule annotation

    Family and domain databases

    InterProiIPR018117. C5_DNA_meth_AS.
    IPR001525. C5_MeTfrase.
    IPR029063. SAM-dependent_MTases-like.
    [Graphical view]
    PANTHERiPTHR10629. PTHR10629. 1 hit.
    PfamiPF00145. DNA_methylase. 1 hit.
    [Graphical view]
    SUPFAMiSSF53335. SSF53335. 1 hit.
    PROSITEiPS00095. C5_MTASE_2. 1 hit.
    PS51679. SAM_MT_C5. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P34883-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDIKNVHIKN HEQTAHAPST LEKIRKVKQG GKLSEQTKTF GSTYRRLDPN    50
    QPSPTVTRSG YRDFIHPFED RMLTVRELAC LQTFPLDWEF TGTRLDSYSS 100
    KRKVTMTQFG QVGNAVPPLL AEAVAKAVSE QLLDVIDEK 139
    Length:139
    Mass (Da):15,760
    Last modified:February 1, 1994 - v1
    Checksum:i8550B7E0194CE006
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M28051 Genomic DNA. Translation: AAA22068.1.
    CP000951 Genomic DNA. No translation available.
    RefSeqiWP_012308460.1. NC_010475.1.
    YP_003828901.1. NC_010475.1.

    Genome annotation databases

    GeneIDi9488071.
    KEGGisyp:SYNPCC7002_A2880.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M28051 Genomic DNA. Translation: AAA22068.1 .
    CP000951 Genomic DNA. No translation available.
    RefSeqi WP_012308460.1. NC_010475.1.
    YP_003828901.1. NC_010475.1.

    3D structure databases

    ProteinModelPortali P34883.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    REBASEi 3283. M.AquI.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 9488071.
    KEGGi syp:SYNPCC7002_A2880.

    Enzyme and pathway databases

    BioCyci SSP32049:GKF7-1189-MONOMER.

    Family and domain databases

    InterProi IPR018117. C5_DNA_meth_AS.
    IPR001525. C5_MeTfrase.
    IPR029063. SAM-dependent_MTases-like.
    [Graphical view ]
    PANTHERi PTHR10629. PTHR10629. 1 hit.
    Pfami PF00145. DNA_methylase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53335. SSF53335. 1 hit.
    PROSITEi PS00095. C5_MTASE_2. 1 hit.
    PS51679. SAM_MT_C5. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Agmenellum quadruplicatum M.AquI, a novel modification methylase."
      Karreman C., de Waard A.
      J. Bacteriol. 172:266-272(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Complete sequence of Synechococcus sp. PCC 7002."
      Li T., Zhao J., Zhao C., Liu Z., Zhao F., Marquardt J., Nomura C.T., Persson S., Detter J.C., Richardson P.M., Lanz C., Schuster S.C., Wang J., Li S., Huang X., Cai T., Yu Z., Luo J., Zhao J., Bryant D.A.
      Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 27264 / PCC 7002 / PR-6.

    Entry informationi

    Entry nameiMTAB_SYNP2
    AccessioniPrimary (citable) accession number: P34883
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1994
    Last sequence update: February 1, 1994
    Last modified: October 1, 2014
    This is version 64 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Restriction enzymes and methylases
      Classification of restriction enzymes and methylases and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3