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Protein

Glucose-6-phosphate isomerase, cytosolic 2B

Gene

PGIC2-B

Organism
Clarkia lewisii (Farewell-to-spring) (Clarkia bottae)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.PROSITE-ProRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei108 – 1081Proton donorPROSITE-ProRule annotation
Active sitei139 – 1391PROSITE-ProRule annotation
Active sitei264 – 2641PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase, cytosolic 2B (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
PGI3
Short name:
PGI
Phosphoglucose isomerase
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:PGIC2-B
OrganismiClarkia lewisii (Farewell-to-spring) (Clarkia bottae)
Taxonomic identifieri3936 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsMyrtalesOnagraceaeOnagroideaeOnagreaeClarkia

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – 317›317Glucose-6-phosphate isomerase, cytosolic 2BPRO_0000180563Add
BLAST

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliP34797.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.PROSITE-ProRule annotation

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

P34797-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LVEKFGIDPN NAFAFWDWVG GRYSVCSAVG VLPLSLQYGF SVVEKFLQGA
60 70 80 90 100
HSIDQHFSSA PFEKNIPVLL GLLSVWNVSF LGYPARAILP YSQALEKLAP
110 120 130 140 150
HIQQVSMESN GKGVSIDGLP LPFESGEIDF GEPGTNGQHS FYQLIHQGRV
160 170 180 190 200
IPCDFIGVVK SQQPVYLKGE VVNNHDELMS NFFAQPDALA YGKTPAQLKK
210 220 230 240 250
ENVSEHLIPH KTFTGNRPSL SILLPTLDAY RIGQLLAIYE HRVAVQGFVW
260 270 280 290 300
GINSFDQWGV ELGKSLATQV RKQLHASRVK GEPVEEGFNF STKTLLTRYL
310
QATTDVPADP STLLPNI
Length:317
Mass (Da):34,993
Last modified:February 1, 1994 - v1
Checksum:i2AD10C29083A0C5D
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X71085 Genomic DNA. Translation: CAA50403.1.
PIRiS41807.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X71085 Genomic DNA. Translation: CAA50403.1.
PIRiS41807.

3D structure databases

ProteinModelPortaliP34797.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Molecular characterization of duplicate cytosolic phosphoglucose isomerase genes in Clarkia and comparison to the single gene in Arabidopsis."
    Thomas B.R., Ford V.S., Pichersky E., Gottlieb L.D.
    Genetics 135:895-905(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiG6PI3_CLALE
AccessioniPrimary (citable) accession number: P34797
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: March 4, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.