Reviewed, UniProtKB/Swiss-Prot P34797 (G6PI3_CLALE)

Names and origin

Protein names

Recommended name:
    Glucose-6-phosphate isomerase, cytosolic 2B
      Short name=GPI
    EC=5.3.1.9
Alternative name(s):
    Phosphoglucose isomerase
    PGI3
      Short name=PGI
    Phosphohexose isomerase
      Short name=PHI

Gene names

Name:

PGIC2-B

Organism

Clarkia lewisii (Farewell-to-spring) (Clarkia bottae)

Taxonomic identifier

3936 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › Myrtales › Onagraceae › Clarkia

Protein attributes

Sequence length	317 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate.
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.
Subunit structure	Homodimer By similarity.
Subcellular location	Cytoplasm.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: UniProtKB-KW glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – 317	›317	Glucose-6-phosphate isomerase, cytosolic 2B		PRO_0000180563
Sites
	Active site	108	1	Proton donor By similarity
	Active site	139	1	By similarity
	Active site	264	1	By similarity
Experimental info
	Non-terminal residue	1	1

Sequences

	Sequence		Length	Mass (Da)
	P34797-1 [UniParc]. Last modified February 1, 1994. Version 1. Checksum: 2AD10C29083A0C5D	FASTA	317	34,993
	10 20 30 40 50 60 LVEKFGIDPN NAFAFWDWVG GRYSVCSAVG VLPLSLQYGF SVVEKFLQGA HSIDQHFSSA 70 80 90 100 110 120 PFEKNIPVLL GLLSVWNVSF LGYPARAILP YSQALEKLAP HIQQVSMESN GKGVSIDGLP 130 140 150 160 170 180 LPFESGEIDF GEPGTNGQHS FYQLIHQGRV IPCDFIGVVK SQQPVYLKGE VVNNHDELMS 190 200 210 220 230 240 NFFAQPDALA YGKTPAQLKK ENVSEHLIPH KTFTGNRPSL SILLPTLDAY RIGQLLAIYE 250 260 270 280 290 300 HRVAVQGFVW GINSFDQWGV ELGKSLATQV RKQLHASRVK GEPVEEGFNF STKTLLTRYL 310 QATTDVPADP STLLPNI

References

[1]	"Molecular characterization of duplicate cytosolic phosphoglucose isomerase genes in Clarkia and comparison to the single gene in Arabidopsis." Thomas B.R., Ford V.S., Pichersky E., Gottlieb L.D. Genetics 135:895-905(1993) [PubMed: 8293986] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	X71085 Genomic DNA. Translation: CAA50403.1.
PIR	S41807.
3D structure databases
HSSP	HSSP built from PDB template 1IAT based on UniProtKB P06744.
ModBase	Search...
Enzyme and pathway databases
BRENDA	5.3.1.9. 308678.
Family and domain databases
InterPro	IPR001672. G6P_Isomerase. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI3_CLALE

Accession

Primary (citable) accession number: P34797

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1994
Last sequence update:	February 1, 1994
Last modified:	October 13, 2009
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)