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Protein

40S ribosomal protein S18

Gene

RPS18A

more
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.By similarity

GO - Molecular functioni

  • mRNA binding Source: TAIR
  • rRNA binding Source: UniProtKB-KW
  • structural constituent of ribosome Source: CAFA

GO - Biological processi

  • ribosome biogenesis Source: GO_Central
  • translation Source: GO_Central
  • translational initiation Source: TAIR

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Enzyme and pathway databases

ReactomeiR-ATH-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-ATH-1799339 SRP-dependent cotranslational protein targeting to membrane
R-ATH-72689 Formation of a pool of free 40S subunits
R-ATH-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-ATH-72702 Ribosomal scanning and start codon recognition
R-ATH-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-ATH-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-ATH-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S18
Gene namesi
Name:RPS18A
Synonyms:PFL
Ordered Locus Names:At1g22780
ORF Names:T22J18.5
AND
Name:RPS18B
Ordered Locus Names:At1g34030
ORF Names:F12G12.15, T15K4.9
AND
Name:RPS18C
Ordered Locus Names:At4g09800
ORF Names:F17A8.150
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componentsi: Chromosome 1, Chromosome 4

Organism-specific databases

AraportiAT1G22780
AT1G34030
AT4G09800
TAIRilocus:2005541 AT4G09800
locus:2009066 AT1G34030
locus:2199670 AT1G22780

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources
ChainiPRO_00001322242 – 15240S ribosomal protein S18Add BLAST151

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiP34788
PRIDEiP34788

PTM databases

iPTMnetiP34788

Expressioni

Gene expression databases

ExpressionAtlasiP34788 baseline and differential
GenevisibleiP34788 AT

Interactioni

Protein-protein interaction databases

BioGridi11868, 3 interactors
24123, 2 interactors
25532, 1 interactor
IntActiP34788, 3 interactors
STRINGi3702.AT4G09800.1

Structurei

3D structure databases

ProteinModelPortaliP34788
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3311 Eukaryota
COG0099 LUCA
HOGENOMiHOG000039877
InParanoidiP34788
KOiK02964
OMAiHKRGQKV
OrthoDBiEOG09360RK6
PhylomeDBiP34788

Family and domain databases

Gene3Di4.10.910.10, 1 hit
HAMAPiMF_01315 Ribosomal_S13_S18, 1 hit
InterProiView protein in InterPro
IPR027437 30s_Rbsml_prot_S13_C
IPR001892 Ribosomal_S13
IPR010979 Ribosomal_S13-like_H2TH
IPR018269 Ribosomal_S13_CS
PfamiView protein in Pfam
PF00416 Ribosomal_S13, 1 hit
PIRSFiPIRSF002134 Ribosomal_S13, 1 hit
SUPFAMiSSF46946 SSF46946, 1 hit
PROSITEiView protein in PROSITE
PS00646 RIBOSOMAL_S13_1, 1 hit
PS50159 RIBOSOMAL_S13_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P34788-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLVANEEFQ HILRVLNTNV DGKQKIMFAL TSIKGIGRRL ANIVCKKADV
60 70 80 90 100
DMNKRAGELS AAEIDNLMTI VANPRQFKIP DWFLNRQKDY KDGKYSQVVS
110 120 130 140 150
NALDMKLRDD LERLKKIRNH RGLRHYWGLR VRGQHTKTTG RRGKTVGVSK

KR
Length:152
Mass (Da):17,545
Last modified:February 1, 1994 - v1
Checksum:i4D060D6614A85092
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti48A → T in AAK43840 (PubMed:14593172).Curated1
Sequence conflicti48A → T in AAL47385 (PubMed:14593172).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z23165 Genomic DNA Translation: CAA80684.1
Z28701 mRNA Translation: CAA82273.1
Z28702 mRNA Translation: CAA82274.1
Z28962 Genomic DNA Translation: CAA82275.1
Y12227 Genomic DNA Translation: CAA72909.1
AC003979 Genomic DNA Translation: AAC25506.1
AC015446 Genomic DNA Translation: AAG12534.1
AC079286 Genomic DNA Translation: AAG12853.1
AL049482 Genomic DNA Translation: CAB39647.1
AL161515 Genomic DNA Translation: CAB78103.1
CP002684 Genomic DNA Translation: AEE30287.1
CP002684 Genomic DNA Translation: AEE31659.1
CP002687 Genomic DNA Translation: AEE82800.1
AF411781 mRNA Translation: AAL06471.1
AF386941 mRNA Translation: AAK62386.1
AF370463 mRNA Translation: AAK43840.1
AY034965 mRNA Translation: AAK59471.1
AY064680 mRNA Translation: AAL47385.1
AY070029 mRNA Translation: AAL47500.1
AY086334 mRNA Translation: AAM64403.1
AY086800 mRNA Translation: AAM63849.1
BT006539 mRNA Translation: AAP21347.1
AY087428 mRNA Translation: AAM64976.1
PIRiS46223 S37496
RefSeqiNP_173692.1, NM_102125.4
NP_192718.1, NM_117048.4
NP_564434.1, NM_103125.5
UniGeneiAt.179
At.180
At.20392
At.33672

Genome annotation databases

EnsemblPlantsiAT1G22780.1; AT1G22780.1; AT1G22780
AT1G34030.1; AT1G34030.1; AT1G34030
AT4G09800.1; AT4G09800.1; AT4G09800
GeneIDi826569
838884
840300
GrameneiAT1G22780.1; AT1G22780.1; AT1G22780
AT1G34030.1; AT1G34030.1; AT1G34030
AT4G09800.1; AT4G09800.1; AT4G09800
KEGGiath:AT1G22780
ath:AT1G34030
ath:AT4G09800

Similar proteinsi

Entry informationi

Entry nameiRS18_ARATH
AccessioniPrimary (citable) accession number: P34788
Secondary accession number(s): Q94K22
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: April 25, 2018
This is version 150 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

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