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Protein

Protein WHI3

Gene

WHI3

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in size control and cell cycle.1 Publication

Miscellaneous

Present with 5730 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • mRNA binding Source: SGD

GO - Biological processi

  • cell cycle Source: UniProtKB-KW
  • cell wall organization or biogenesis Source: CACAO
  • cytoplasmic sequestering of protein Source: SGD
  • invasive growth in response to glucose limitation Source: SGD
  • mRNA destabilization Source: SGD
  • positive regulation of cell size Source: CACAO
  • positive regulation of cell-substrate adhesion Source: CACAO
  • positive regulation of response to extracellular stimulus Source: CACAO
  • positive regulation of transcription, DNA-templated Source: CACAO
  • positive regulation of translation Source: CACAO
  • positive regulation of translational elongation Source: CACAO
  • pseudohyphal growth Source: SGD
  • regulation of mRNA catabolic process Source: SGD
  • traversing start control point of mitotic cell cycle Source: SGD

Keywordsi

Molecular functionRNA-binding
Biological processCell cycle

Enzyme and pathway databases

BioCyciYEAST:G3O-33207-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein WHI3
Gene namesi
Name:WHI3
Ordered Locus Names:YNL197C
ORF Names:N1382
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIV

Organism-specific databases

EuPathDBiFungiDB:YNL197C
SGDiS000005141 WHI3

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000820051 – 661Protein WHI3Add BLAST661

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei231PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP34761
PaxDbiP34761
PRIDEiP34761
TopDownProteomicsiP34761

PTM databases

iPTMnetiP34761

Interactioni

Protein-protein interaction databases

BioGridi35636, 535 interactors
IntActiP34761, 16 interactors
MINTiP34761
STRINGi4932.YNL197C

Structurei

3D structure databases

ProteinModelPortaliP34761
SMRiP34761
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini538 – 625RRMPROSITE-ProRule annotationAdd BLAST88

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi247 – 277Gln-richAdd BLAST31

Phylogenomic databases

GeneTreeiENSGT00530000067542
HOGENOMiHOG000074699
InParanoidiP34761
OMAiGNGHGPM
OrthoDBiEOG092C448I

Family and domain databases

Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit

Sequencei

Sequence statusi: Complete.

P34761-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQSSVYFDQT GSFASSSDNV VSSTTNTHNI SPSHRSSLNL NTTSHPHEAS
60 70 80 90 100
GRGSASGELY LNDTNSPLAI SSMLNTLALG SMPQDIASSN ISNHDNNIKG
110 120 130 140 150
SYSLKLSNVA KDITLRECYA IFALAEGVKS IELQKKNSSS SITSASLEDE
160 170 180 190 200
NDIFIIARFE LLNLAINYAV ILNSKNELFG PSFPNKTTVE IIDDTTKNLV
210 220 230 240 250
SFPSSAIFND TSRLNKSNSG MKRPSLLSQR SRFSFSDPFS NDSPLSQQQS
260 270 280 290 300
QQQQQQPQQP QQHSTQKHSP QQCNQQQVNS SIPLSSQGQV IGLHSNHSHQ
310 320 330 340 350
DLSVESTIQT SDIGKSFLLR DNTEINEKIW GTSGIPSSIN GYMSTPQPST
360 370 380 390 400
PTLEWGNTSA SQHGSSFFLP SAASTAIAPT NSNTSANANA SSNNGASNNG
410 420 430 440 450
ANQALSASSQ QPMMQIGNTI NTSLTSSNSL PPYGLMSSQS QHISNMVNTS
460 470 480 490 500
DMNITPQKQN RFMQQPQPEH MYPVNQSNTP QKVPPARLSS SRNSHKNNST
510 520 530 540 550
TSLSSNITGS ASISQADLSL LARIPPPANP ADQNPPCNTL YVGNLPSDAT
560 570 580 590 600
EQELRQLFSG QEGFRRLSFR NKNTTSNGHS HGPMCFVEFD DVSFATRALA
610 620 630 640 650
ELYGRQLPRS TVSSKGGIRL SFSKNPLGVR GPNSRRGGSG NPNPNVNMLS
660
SYNSNVGHIK N
Length:661
Mass (Da):71,253
Last modified:February 1, 1994 - v1
Checksum:i47A6B9716CF96043
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U01095 Genomic DNA Translation: AAA03320.1
X78898 Genomic DNA Translation: CAA55511.1
Z71473 Genomic DNA Translation: CAA96092.1
BK006947 Genomic DNA Translation: DAA10356.1
PIRiS50734
RefSeqiNP_014202.1, NM_001183035.1

Genome annotation databases

EnsemblFungiiYNL197C; YNL197C; YNL197C
GeneIDi855524
KEGGisce:YNL197C

Similar proteinsi

Entry informationi

Entry nameiWHI3_YEAST
AccessioniPrimary (citable) accession number: P34761
Secondary accession number(s): D6W0Z0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: May 23, 2018
This is version 145 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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