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Protein

Fimbrial assembly protein PilQ

Gene

pilQ

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane.

GO - Molecular functioni

GO - Biological processi

  • protein secretion Source: InterPro
  • type IV pilus biogenesis Source: PseudoCAP

Keywordsi

Biological processFimbrium biogenesis, Protein transport, Transport

Enzyme and pathway databases

BioCyciPAER208964:G1FZ6-5156-MONOMER

Protein family/group databases

TCDBi1.B.22.2.1 the outer bacterial membrane secretin (secretin) family

Names & Taxonomyi

Protein namesi
Recommended name:
Fimbrial assembly protein PilQ
Gene namesi
Name:pilQ
Ordered Locus Names:PA5040
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA5040

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_000001311925 – 714Fimbrial assembly protein PilQAdd BLAST690

Proteomic databases

PaxDbiP34750
PRIDEiP34750

Interactioni

Protein-protein interaction databases

STRINGi208964.PA5040

Structurei

3D structure databases

ProteinModelPortaliP34750
SMRiP34750
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GSP D family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105E4G Bacteria
COG4796 LUCA
HOGENOMiHOG000255072
InParanoidiP34750
KOiK02666
OMAiQNVPWDQ
PhylomeDBiP34750

Family and domain databases

Gene3Di3.30.1370.120, 1 hit
InterProiView protein in InterPro
IPR021731 AMIN_dom
IPR001775 GspD/PilQ
IPR005644 NolW-like
IPR038591 NolW-like_sf
IPR013355 Pilus_4_PilQ
IPR011662 Secretin/TonB_short_N
IPR004846 T2SS/T3SS
IPR004845 T2SS_GspD_CS
PfamiView protein in Pfam
PF11741 AMIN, 1 hit
PF00263 Secretin, 1 hit
PF03958 Secretin_N, 1 hit
PF07660 STN, 1 hit
PRINTSiPR00811 BCTERIALGSPD
SMARTiView protein in SMART
SM00965 STN, 1 hit
TIGRFAMsiTIGR02515 IV_pilus_PilQ, 1 hit
PROSITEiView protein in PROSITE
PS00875 T2SP_D, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P34750-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSGLSRLGI ALLAAMFAPA LLAADLEKLD VAALPGDRVE LKLQFDEPVA
60 70 80 90 100
APRGYTIEQP ARIALDLPGV QNKLGTKNRE LSVGNTRSVT VVEAKDRTRL
110 120 130 140 150
IINLTALSSY TTRVEGNNLF VVVGNSPAGA SVASAAPVKA SPAPASYAQP
160 170 180 190 200
IKPKPYVPAG RAIRNIDFQR GEKGEGNVVI DLSDPTLSPD IQEQGGKIRL
210 220 230 240 250
DFAKTQLPDA LRVRLDVKDF ATPVQFVNAS AQSDRTSITI EPSGLYDYLV
260 270 280 290 300
YQTDNRLTVS IKPMTTEDAE RRKKDNFAYT GEKLSLNFQD IDVRSVLQLI
310 320 330 340 350
ADFTDLNLVA SDTVQGNITL RLQNVPWDQA LDLVLKTKGL DKRKLGNVLL
360 370 380 390 400
VAPADEIAAR ERQELEAQKQ IAELAPLRRE LIQVNYAKAA DIAKLFQSVT
410 420 430 440 450
SDGGQEGKEG GRGSITVDDR TNSIIAYQPQ ERLDELRRIV SQLDIPVRQV
460 470 480 490 500
MIEARIVEAN VGYDKSLGVR WGGAYHKGNW SGYGKDGNIG IKDEDGMNCG
510 520 530 540 550
PIAGSCTFPT TGTSKSPSPF VDLGAKDATS GIGIGFITDN IILDLQLSAM
560 570 580 590 600
EKTGNGEIVS QPKVVTSDKE TAKILKGSEV PYQEASSSGA TSTSFKEAAL
610 620 630 640 650
SLEVTPQITP DNRIIVEVKV TKDAPDYQNM LNGVPPINKN EVNAKILVND
660 670 680 690 700
GETIVIGGVF SNEQSKSVEK VPFLGELPYL GRLFRRDTVT DRKNELLVFL
710
TPRIMNNQAI AIGR
Length:714
Mass (Da):77,379
Last modified:December 8, 2000 - v2
Checksum:i9A748EE8286FBAB5
GO

Sequence cautioni

The sequence AAA16704 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti391D → E in AAA16704 (PubMed:7901733).Curated1
Sequence conflicti411G → A in AAA16704 (PubMed:7901733).Curated1
Sequence conflicti547 – 558LSAME…GNGEI → PVGDGKDRQRRV in AAA16704 (PubMed:7901733).CuratedAdd BLAST12

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L13865 Unassigned DNA Translation: AAA16704.1 Different initiation.
AE004091 Genomic DNA Translation: AAG08425.1
PIRiA83016
S37345
RefSeqiNP_253727.1, NC_002516.2
WP_003114575.1, NC_002516.2

Genome annotation databases

EnsemblBacteriaiAAG08425; AAG08425; PA5040
GeneIDi880962
KEGGipae:PA5040
PATRICifig|208964.12.peg.5284

Similar proteinsi

Entry informationi

Entry nameiPILQ_PSEAE
AccessioniPrimary (citable) accession number: P34750
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: December 8, 2000
Last modified: March 28, 2018
This is version 115 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health