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P34724

- PHOA_ASPNG

UniProt

P34724 - PHOA_ASPNG

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Protein

Acid phosphatase

Gene
phoA
Organism
Aspergillus niger
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei216 – 2161Proton donor By similarity

GO - Molecular functioni

  1. acid phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Acid phosphatase (EC:3.1.3.2)
Gene namesi
Name:phoA
OrganismiAspergillus niger
Taxonomic identifieri5061 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919 Reviewed predictionAdd
BLAST
Chaini20 – 417398Acid phosphatasePRO_0000023978Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi122 – 1221N-linked (GlcNAc...) Reviewed prediction
Glycosylationi187 – 1871N-linked (GlcNAc...) Reviewed prediction
Glycosylationi209 – 2091N-linked (GlcNAc...) Reviewed prediction
Glycosylationi218 – 2181N-linked (GlcNAc...) Reviewed prediction
Glycosylationi333 – 3331N-linked (GlcNAc...) Reviewed prediction
Glycosylationi383 – 3831N-linked (GlcNAc...) Reviewed prediction

Post-translational modificationi

The N-terminus is blocked.

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliP34724.

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG11964.

Family and domain databases

InterProiIPR007312. Phosphoesterase.
[Graphical view]
PfamiPF04185. Phosphoesterase. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P34724-1 [UniParc]FASTAAdd to Basket

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MFTKQSLVTL LGGLSLAVAQ TTTEGYPSLA EIRAAQATVQ PYSPVSNVKG    50
LTFNRFVNIW LENTDFDAAA ATEHLPVLAK KGLLLNNFWA VTHPSEPNYC 100
RHLPLGDTFG MDNDDFHQIP SNVSTIADLF DTKNIAWGEY QEGLPYPGYQ 150
GYRYPESGAN DYVRNRNPLI LFDSVTEDAL RLRQIKNFSS FYDDLENHRL 200
PQYMFITPNM TNDGHDTNIT FSGDWTWGFL SELLENDYFT KDTLIMLTFD 250
ETGTYEIGNN IYTFLLGGAV PDDLLGTKDD TFYTHYSVIA SLSTNWGLPS 300
LGRWDCGANL FSWLAKKTGY VNYEVDTSNL YMNETHWGPL SDDDYSEYYA 350
GWPVPTTDAS CSAGNGILST VKKTYEGLTA TFNYTTPFPY DSRSGNNVGV 400
KYSRTLKNGK VESGTSE 417
Length:417
Mass (Da):46,736
Last modified:February 1, 1994 - v1
Checksum:i896FD2AF541C69C8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L20566 Genomic DNA. Translation: AAA62393.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L20566 Genomic DNA. Translation: AAA62393.1 .

3D structure databases

ProteinModelPortali P34724.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

eggNOGi NOG11964.

Family and domain databases

InterProi IPR007312. Phosphoesterase.
[Graphical view ]
Pfami PF04185. Phosphoesterase. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "An acid phosphatase from Aspergillus ficuum has homology to Penicillium chrysogenum PhoA."
    Ehrlich K.C., Montalbano B.G., Mullaney E.J., Dischinger H.C. Jr., Ullah A.H.J.
    Biochem. Biophys. Res. Commun. 204:63-68(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE.
    Strain: NRRL 3135 / Van Tieghem / Ficuum.

Entry informationi

Entry nameiPHOA_ASPNG
AccessioniPrimary (citable) accession number: P34724
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: April 16, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

External Data

Dasty 3

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