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Reviewed, UniProtKB/Swiss-Prot P34724 (PHOA_ASPNG)

Last modified June 16, 2009. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

Names and origin

Protein namesRecommended name:
    Acid phosphatase
    EC=3.1.3.2
Gene names
Name: phoA
OrganismAspergillus niger
Taxonomic identifier5061 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesTrichocomaceaemitosporic TrichocomaceaeAspergillus

Protein attributes

Sequence length417 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level.

General annotation (Comments)

Catalytic activity

A phosphate monoester + H2O = an alcohol + phosphate.

Subcellular location

Secreted.

Post-translational modification

The N-terminus is blocked.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   Molecular functionHydrolase
   PTMGlycoprotein
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Cellular componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionacid phosphatase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 Potential
Chain20 – 417398Acid phosphatase
PRO_0000023978

Sites

Active site2161Proton donor By similarity

Amino acid modifications

Glycosylation1221N-linked (GlcNAc...) Potential
Glycosylation1871N-linked (GlcNAc...) Potential
Glycosylation2091N-linked (GlcNAc...) Potential
Glycosylation2181N-linked (GlcNAc...) Potential
Glycosylation3331N-linked (GlcNAc...) Potential
Glycosylation3831N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
P34724-1 [UniParc].

Last modified February 1, 1994. Version 1.
Checksum: 896FD2AF541C69C8

FASTA41746,736
        10         20         30         40         50         60 
MFTKQSLVTL LGGLSLAVAQ TTTEGYPSLA EIRAAQATVQ PYSPVSNVKG LTFNRFVNIW 

        70         80         90        100        110        120 
LENTDFDAAA ATEHLPVLAK KGLLLNNFWA VTHPSEPNYC RHLPLGDTFG MDNDDFHQIP 

       130        140        150        160        170        180 
SNVSTIADLF DTKNIAWGEY QEGLPYPGYQ GYRYPESGAN DYVRNRNPLI LFDSVTEDAL 

       190        200        210        220        230        240 
RLRQIKNFSS FYDDLENHRL PQYMFITPNM TNDGHDTNIT FSGDWTWGFL SELLENDYFT 

       250        260        270        280        290        300 
KDTLIMLTFD ETGTYEIGNN IYTFLLGGAV PDDLLGTKDD TFYTHYSVIA SLSTNWGLPS 

       310        320        330        340        350        360 
LGRWDCGANL FSWLAKKTGY VNYEVDTSNL YMNETHWGPL SDDDYSEYYA GWPVPTTDAS 

       370        380        390        400        410 
CSAGNGILST VKKTYEGLTA TFNYTTPFPY DSRSGNNVGV KYSRTLKNGK VESGTSE 

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References

[1]"An acid phosphatase from Aspergillus ficuum has homology to Penicillium chrysogenum PhoA."
Ehrlich K.C., Montalbano B.G., Mullaney E.J., Dischinger H.C. Jr., Ullah A.H.J.
Biochem. Biophys. Res. Commun. 204:63-68(1994) [PubMed: 7945393] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE.
Strain: NRRL 3135 / Van Tieghem / Ficuum.

Cross-references

Sequence databases

L20566 Genomic DNA. Translation: AAA62393.1.

3D structure databases

ModBaseSearch...

Enzyme and pathway databases

BRENDA3.1.3.2. 277.

Family and domain databases

InterProIPR007312. Phosphoesterase.
[Graphical view]
PfamPF04185. Phosphoesterase. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePHOA_ASPNG
AccessionPrimary (citable) accession number: P34724
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: June 16, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information