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P34717

- NSP3_ROTBS

UniProt

P34717 - NSP3_ROTBS

Protein

Non-structural protein 3

Gene
N/A
Organism
Rotavirus C (isolate Cow/Japan/Shintoku/1991) (RV-C)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 1 (01 Feb 1994)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei333 – 3342Cleavage; by autolysisSequence Analysis

    GO - Molecular functioni

    1. RNA binding Source: UniProtKB-KW

    Keywords - Ligandi

    RNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Non-structural protein 3
    Short name:
    NSP3
    Cleaved into the following 2 chains:
    OrganismiRotavirus C (isolate Cow/Japan/Shintoku/1991) (RV-C)
    Taxonomic identifieri33723 [NCBI]
    Taxonomic lineageiVirusesdsRNA virusesReoviridaeSedoreovirinaeRotavirus
    Virus hostiBos taurus (Bovine) [TaxID: 9913]

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 402402Non-structural protein 3PRO_0000149543Add
    BLAST
    Chaini1 – 333333p38By similarityPRO_0000369883Add
    BLAST
    Chaini334 – 40269p8By similarityPRO_0000369884Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliP34717.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini334 – 40269DRBMPROSITE-ProRule annotationAdd
    BLAST

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili87 – 11327Sequence AnalysisAdd
    BLAST
    Coiled coili147 – 18135Sequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Belongs to the rotavirus C NSP3 family.Curated
    Contains 1 DRBM (double-stranded RNA-binding) domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Coiled coil

    Family and domain databases

    Gene3Di3.30.160.20. 1 hit.
    InterProiIPR014720. dsRNA-bd_dom.
    IPR002873. Rotavirus_NSP3.
    [Graphical view]
    PfamiPF00035. dsrm. 1 hit.
    PF01665. Rota_NSP3. 1 hit.
    [Graphical view]
    SMARTiSM00358. DSRM. 1 hit.
    [Graphical view]
    SUPFAMiSSF69903. SSF69903. 1 hit.
    PROSITEiPS50137. DS_RBD. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P34717-1 [UniParc]FASTAAdd to Basket

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    MATQASVEWI FNVAGSAASA SLAKSIKDAG GSEDFAKYVV ARFYDNYKDS    50
    IDDSGIYNAC MGRARTVDKA LNDSRLAERN EEWHTNLATI RRLDLELAEL 100
    KLMLSNLGMK REERVLNSMF SVTREEGRSS NVVMLKQNAV KMIEEGKLKI 150
    KVEKNENYTE SLKNKIEELE CIIGAFEKGK EINIALDAMT GEVRLDGDSC 200
    SYNSTAAFVS TIMGTPIKMY DESNKPLFDV GKYINPKHVI DKMIESEIPI 250
    FKSDYRNNES PDFDAWNENS NLKIVSVNDC HAICVFKFEN EWWCFDDGRL 300
    RKYNGIGNPL IVANSKFQID RILISGDIEL NPGPNALVKL NDCITKYNLK 350
    IICTFDVNLD DDGSIMYICY LKVGSAEATG NGCSKKEAKR RAAVSILDQL 400
    GM 402
    Length:402
    Mass (Da):45,081
    Last modified:February 1, 1994 - v1
    Checksum:iEBF553E90D955D49
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L12390 Genomic RNA. No translation available.
    PIRiS35639.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L12390 Genomic RNA. No translation available.
    PIRi S35639.

    3D structure databases

    ProteinModelPortali P34717.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.30.160.20. 1 hit.
    InterProi IPR014720. dsRNA-bd_dom.
    IPR002873. Rotavirus_NSP3.
    [Graphical view ]
    Pfami PF00035. dsrm. 1 hit.
    PF01665. Rota_NSP3. 1 hit.
    [Graphical view ]
    SMARTi SM00358. DSRM. 1 hit.
    [Graphical view ]
    SUPFAMi SSF69903. SSF69903. 1 hit.
    PROSITEi PS50137. DS_RBD. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequences of genes 6 and 10 of a bovine group C rotavirus."
      Jiang B., Tsunemitsu H., Gentsch J.R., Saif L.J., Glass R.I.
      Nucleic Acids Res. 21:2250-2250(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

    Entry informationi

    Entry nameiNSP3_ROTBS
    AccessioniPrimary (citable) accession number: P34717
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1994
    Last sequence update: February 1, 1994
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3