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P34717

- NSP3_ROTBS

UniProt

P34717 - NSP3_ROTBS

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Protein

Non-structural protein 3

Gene
N/A
Organism
Rotavirus C (isolate Cow/Japan/Shintoku/1991) (RV-C)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei333 – 3342Cleavage; by autolysisSequence Analysis

GO - Molecular functioni

  1. RNA binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Non-structural protein 3
Short name:
NSP3
Cleaved into the following 2 chains:
OrganismiRotavirus C (isolate Cow/Japan/Shintoku/1991) (RV-C)
Taxonomic identifieri33723 [NCBI]
Taxonomic lineageiVirusesdsRNA virusesReoviridaeSedoreovirinaeRotavirus
Virus hostiBos taurus (Bovine) [TaxID: 9913]

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 402402Non-structural protein 3PRO_0000149543Add
BLAST
Chaini1 – 333333p38By similarityPRO_0000369883Add
BLAST
Chaini334 – 40269p8By similarityPRO_0000369884Add
BLAST

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliP34717.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini334 – 40269DRBMPROSITE-ProRule annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili87 – 11327Sequence AnalysisAdd
BLAST
Coiled coili147 – 18135Sequence AnalysisAdd
BLAST

Sequence similaritiesi

Belongs to the rotavirus C NSP3 family.Curated
Contains 1 DRBM (double-stranded RNA-binding) domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Family and domain databases

Gene3Di3.30.160.20. 1 hit.
InterProiIPR014720. dsRNA-bd_dom.
IPR002873. Rotavirus_NSP3.
[Graphical view]
PfamiPF00035. dsrm. 1 hit.
PF01665. Rota_NSP3. 1 hit.
[Graphical view]
SMARTiSM00358. DSRM. 1 hit.
[Graphical view]
SUPFAMiSSF69903. SSF69903. 1 hit.
PROSITEiPS50137. DS_RBD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P34717 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MATQASVEWI FNVAGSAASA SLAKSIKDAG GSEDFAKYVV ARFYDNYKDS
60 70 80 90 100
IDDSGIYNAC MGRARTVDKA LNDSRLAERN EEWHTNLATI RRLDLELAEL
110 120 130 140 150
KLMLSNLGMK REERVLNSMF SVTREEGRSS NVVMLKQNAV KMIEEGKLKI
160 170 180 190 200
KVEKNENYTE SLKNKIEELE CIIGAFEKGK EINIALDAMT GEVRLDGDSC
210 220 230 240 250
SYNSTAAFVS TIMGTPIKMY DESNKPLFDV GKYINPKHVI DKMIESEIPI
260 270 280 290 300
FKSDYRNNES PDFDAWNENS NLKIVSVNDC HAICVFKFEN EWWCFDDGRL
310 320 330 340 350
RKYNGIGNPL IVANSKFQID RILISGDIEL NPGPNALVKL NDCITKYNLK
360 370 380 390 400
IICTFDVNLD DDGSIMYICY LKVGSAEATG NGCSKKEAKR RAAVSILDQL

GM
Length:402
Mass (Da):45,081
Last modified:February 1, 1994 - v1
Checksum:iEBF553E90D955D49
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L12390 Genomic RNA. No translation available.
PIRiS35639.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L12390 Genomic RNA. No translation available.
PIRi S35639.

3D structure databases

ProteinModelPortali P34717.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.30.160.20. 1 hit.
InterProi IPR014720. dsRNA-bd_dom.
IPR002873. Rotavirus_NSP3.
[Graphical view ]
Pfami PF00035. dsrm. 1 hit.
PF01665. Rota_NSP3. 1 hit.
[Graphical view ]
SMARTi SM00358. DSRM. 1 hit.
[Graphical view ]
SUPFAMi SSF69903. SSF69903. 1 hit.
PROSITEi PS50137. DS_RBD. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Nucleotide sequences of genes 6 and 10 of a bovine group C rotavirus."
    Jiang B., Tsunemitsu H., Gentsch J.R., Saif L.J., Glass R.I.
    Nucleic Acids Res. 21:2250-2250(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiNSP3_ROTBS
AccessioniPrimary (citable) accession number: P34717
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: October 1, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3