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P34717 (NSP3_ROTBS) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Non-structural protein 3

Short name=NSP3

Cleaved into the following 2 chains:

  1. p38
  2. p8
OrganismRotavirus C (isolate Cow/Japan/Shintoku/1991) (RV-C)
Taxonomic identifier33723 [NCBI]
Taxonomic lineageVirusesdsRNA virusesReoviridaeSedoreovirinaeRotavirus
Virus hostBos taurus (Bovine) [TaxID: 9913]

Protein attributes

Sequence length402 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the rotavirus C NSP3 family.

Contains 1 DRBM (double-stranded RNA-binding) domain.

Ontologies

Keywords
   DomainCoiled coil
   LigandRNA-binding
Gene Ontology (GO)
   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 402402Non-structural protein 3
PRO_0000149543
Chain1 – 333333p38 By similarity
PRO_0000369883
Chain334 – 40269p8 By similarity
PRO_0000369884

Regions

Domain334 – 40269DRBM
Coiled coil87 – 11327 Potential
Coiled coil147 – 18135 Potential

Sites

Site333 – 3342Cleavage; by autolysis Potential

Sequences

Sequence LengthMass (Da)Tools
P34717 [UniParc].

Last modified February 1, 1994. Version 1.
Checksum: EBF553E90D955D49

FASTA40245,081
        10         20         30         40         50         60 
MATQASVEWI FNVAGSAASA SLAKSIKDAG GSEDFAKYVV ARFYDNYKDS IDDSGIYNAC 

        70         80         90        100        110        120 
MGRARTVDKA LNDSRLAERN EEWHTNLATI RRLDLELAEL KLMLSNLGMK REERVLNSMF 

       130        140        150        160        170        180 
SVTREEGRSS NVVMLKQNAV KMIEEGKLKI KVEKNENYTE SLKNKIEELE CIIGAFEKGK 

       190        200        210        220        230        240 
EINIALDAMT GEVRLDGDSC SYNSTAAFVS TIMGTPIKMY DESNKPLFDV GKYINPKHVI 

       250        260        270        280        290        300 
DKMIESEIPI FKSDYRNNES PDFDAWNENS NLKIVSVNDC HAICVFKFEN EWWCFDDGRL 

       310        320        330        340        350        360 
RKYNGIGNPL IVANSKFQID RILISGDIEL NPGPNALVKL NDCITKYNLK IICTFDVNLD 

       370        380        390        400 
DDGSIMYICY LKVGSAEATG NGCSKKEAKR RAAVSILDQL GM 

« Hide

References

[1]"Nucleotide sequences of genes 6 and 10 of a bovine group C rotavirus."
Jiang B., Tsunemitsu H., Gentsch J.R., Saif L.J., Glass R.I.
Nucleic Acids Res. 21:2250-2250(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L12390 Genomic RNA. No translation available.
PIRS35639.

3D structure databases

ProteinModelPortalP34717.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.30.160.20. 1 hit.
InterProIPR014720. dsRNA-bd_dom.
IPR002873. Rotavirus_NSP3.
[Graphical view]
PfamPF00035. dsrm. 1 hit.
PF01665. Rota_NSP3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
[Graphical view]
SUPFAMSSF69903. SSF69903. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNSP3_ROTBS
AccessionPrimary (citable) accession number: P34717
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: October 16, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families