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Protein

Non-structural protein 3

Gene
N/A
Organism
Rotavirus C (isolate RVC/Cow/Japan/Shintoku/1991/G2P[3]) (RV-C)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

May play a role in stimulating the translation of viral mRNAs.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-binding
Biological processTranslation regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Non-structural protein 3UniRule annotation
Short name:
NSP3UniRule annotation
Alternative name(s):
NCVP4UniRule annotation
Non-structural RNA-binding protein 34UniRule annotation
Short name:
NS34UniRule annotation
Cleaved into the following 2 chains:
OrganismiRotavirus C (isolate RVC/Cow/Japan/Shintoku/1991/G2P[3]) (RV-C)
Taxonomic identifieri33723 [NCBI]
Taxonomic lineageiVirusesdsRNA virusesReoviridaeSedoreovirinaeRotavirus
Virus hostiBos taurus (Bovine) [TaxID: 9913]

Subcellular locationi

  • Host cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Host cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001495431 – 402Non-structural protein 3Add BLAST402
ChainiPRO_00003698831 – 333p38By similarityAdd BLAST333
ChainiPRO_0000369884334 – 402p8By similarityAdd BLAST69

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei333 – 334Cleavage; by autolysisSequence analysis2

Structurei

3D structure databases

ProteinModelPortaliP34717
SMRiP34717
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini334 – 402DRBMPROSITE-ProRule annotationAdd BLAST69

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili87 – 113Sequence analysisAdd BLAST27
Coiled coili147 – 181Sequence analysisAdd BLAST35

Sequence similaritiesi

Belongs to the rotavirus NSP3 family.UniRule annotation

Keywords - Domaini

Coiled coil

Family and domain databases

HAMAPiMF_04090 ROTA_NSP3, 1 hit
InterProiView protein in InterPro
IPR014720 dsRBD_dom
IPR036082 NSP3_sf
IPR002873 Rotavirus_NSP3
PfamiView protein in Pfam
PF01665 Rota_NSP3, 1 hit
SMARTiView protein in SMART
SM00358 DSRM, 1 hit
SUPFAMiSSF69903 SSF69903, 1 hit
PROSITEiView protein in PROSITE
PS50137 DS_RBD, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P34717-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATQASVEWI FNVAGSAASA SLAKSIKDAG GSEDFAKYVV ARFYDNYKDS
60 70 80 90 100
IDDSGIYNAC MGRARTVDKA LNDSRLAERN EEWHTNLATI RRLDLELAEL
110 120 130 140 150
KLMLSNLGMK REERVLNSMF SVTREEGRSS NVVMLKQNAV KMIEEGKLKI
160 170 180 190 200
KVEKNENYTE SLKNKIEELE CIIGAFEKGK EINIALDAMT GEVRLDGDSC
210 220 230 240 250
SYNSTAAFVS TIMGTPIKMY DESNKPLFDV GKYINPKHVI DKMIESEIPI
260 270 280 290 300
FKSDYRNNES PDFDAWNENS NLKIVSVNDC HAICVFKFEN EWWCFDDGRL
310 320 330 340 350
RKYNGIGNPL IVANSKFQID RILISGDIEL NPGPNALVKL NDCITKYNLK
360 370 380 390 400
IICTFDVNLD DDGSIMYICY LKVGSAEATG NGCSKKEAKR RAAVSILDQL

GM
Length:402
Mass (Da):45,081
Last modified:February 1, 1994 - v1
Checksum:iEBF553E90D955D49
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L12390 Genomic RNA No translation available.
PIRiS35639

Similar proteinsi

Entry informationi

Entry nameiNSP3_ROTBS
AccessioniPrimary (citable) accession number: P34717
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: April 25, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health