Reviewed, UniProtKB/Swiss-Prot P34715 (EF1G_TRYCR)

Names and origin

Protein names	Recommended name:     Elongation factor 1-gamma       Short name=EF-1-gamma Alternative name(s):     eEF-1B gamma
Organism	Trypanosoma cruzi
Taxonomic identifier	5693 [NCBI]
Taxonomic lineage	Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Trypanosoma › Schizotrypanum

Protein attributes

Sequence length	411 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Probably plays a role in anchoring the complex to other cellular components.
Subunit structure	EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
Sequence similarities	Contains 1 EF-1-gamma C-terminal domain. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain.

Ontologies

Keywords
Biological process	Protein biosynthesis
Molecular function	Elongation factor
Gene Ontology (GO)
Biological process	translational elongation Inferred from electronic annotation. Source: InterPro
Cellular component	eukaryotic translation elongation factor 1 complex Inferred from electronic annotation. Source: InterPro
Molecular function	translation elongation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 411	411	Elongation factor 1-gamma		PRO_0000208825
Regions
	Domain	3 – 84	82	GST N-terminal
	Domain	90 – 216	127	GST C-terminal
	Domain	255 – 411	157	EF-1-gamma C-terminal

Sequences

	Sequence		Length	Mass (Da)
	P34715-1 [UniParc]. Last modified February 1, 1994. Version 1. Checksum: F61463694B73CD80	FASTA	411	46,567
	10 20 30 40 50 60 MSLTLWSGVN PENARTHKLL AAAALANVAV TLKACEYGRE NETAEYCRNC SPCGRYPVLQ 70 80 90 100 110 120 TEEGCVFESN AILRHIARLD RSGGFLYGRT PLEGSQVDMW LDFSATELDA ASEPFVHHAF 130 140 150 160 170 180 RGEPLPANAM DRVHEVLRAL EAWLETRTFL VGERMTVADV AVAFALQWHY RLNGAEGEAL 190 200 210 220 230 240 TKKYRNAYRM YNTVMQQPKT VEVLRSQGAT FGAREGGAKG QGRGCARPGR EEAERAAAAA 250 260 270 280 290 300 DGAEEEDEAP REKKKPNPLD ELPPSPFVLD AFKREYSNTD TRTVAAPYFF QHYDAAGYTT 310 320 330 340 350 360 FWCRYKYNED NKMQFMTANL IRGWFQRMEH VRKYAFGVAL IIGEERRHDI VALWVFRGRG 370 380 390 400 410 MPAIVEDVED TELFDWEEVA DVAAQRERIT DYLSWEGPTI PRPVLEGRVF K

References

[1]

"Nucleotide sequence of a Trypanosoma cruzi cDNA encoding a protein homologous to mammalian EF1 gamma." Billaut-Mulot O., Pommier V., Schoeneck R., Plumas-Marty B., Taibi A., Loyens M., Capron A., Ouaissi M.A. Nucleic Acids Res. 21:3901-3901(1993) [PubMed: 8367313] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: Y.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L17307 mRNA. Translation: AAA02936.1.
PIR	S41648.
3D structure databases
HSSP	HSSP built from PDB template 1PBU based on UniProtKB P26641.
ModBase	Search...
Family and domain databases
InterPro	IPR010987. Glutathione-S-Trfase_C-like. IPR004045. Glutathione_S-Trfase_N. IPR017933. Glutathione_S_Trfase/Cl_chnl_C. IPR004046. GST_C. IPR001662. Transl_elong_EF1_G_con. [Graphical view]
Gene3D	G3DSA:1.20.1050.10. GST_C_like. 1 hit. G3DSA:3.30.70.1010. Transl_elong_EF1_G_con. 1 hit.
Pfam	PF00647. EF1G. 1 hit. PF00043. GST_C. 1 hit. PF02798. GST_N. 1 hit. [Graphical view]
ProDom	PD006217. EF1_G. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS50040. EF1G_C. 1 hit. PS50405. GST_CTER. 1 hit. PS50404. GST_NTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EF1G_TRYCR

Accession

Primary (citable) accession number: P34715

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1994
Last sequence update:	February 1, 1994
Last modified:	June 16, 2009
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)